Patents by Inventor Carlos Buesa Arjol

Carlos Buesa Arjol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SELECTIVE LSD1 AND DUAL LSD1/MAO-B INHIBITORS FOR MODULATING DISEASES ASSOCIATED WITH ALTERATIONS IN PROTEIN CONFORMATION
    Publication number: 20160081947
    Abstract: The invention relates to methods and compositions for the treatment or prevention of protein conformation disorders. In particular, the invention relates to an LSD1 inhibitor for use in treating or preventing a protein conformation disorder, such as, e.g., Huntington Disease.
    Type: Application
    Filed: April 1, 2015
    Publication date: March 24, 2016
    Inventors: Tamara MAES, Carlos BUESA ARJOL
  • CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS
    Publication number: 20130303545
    Abstract: The invention relates to methods and compositions for the treatment or prevention of protein conformation disorders. In particular, the invention relates to an LSD1 inhibitor for use in treating or preventing a protein conformation disorder, such as, e.g., Huntington Disease.
    Type: Application
    Filed: September 20, 2011
    Publication date: November 14, 2013
    Inventors: Tamara Maes, Carlos Buesa Arjol
  • Molecular diagnostic method and treatment in dementia with Lewy bodies
    Publication number: 20100285483
    Abstract: The invention describes methods of molecular diagnosis of a concrete form of ?-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 11, 2010
    Applicant: Oryzon Genomics, S.A.
    Inventors: Tamara Maes, Carlos Buesa Arjol, Marta Barrachina Castillo, Isidro Ferrer Abizanda
  • Molecular diagnostic method for dementia with lewy bodies
    Patent number: 7745127
    Abstract: The present invention describes methods of molecular diagnosis of a concrete form of a-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB.
    Type: Grant
    Filed: July 18, 2005
    Date of Patent: June 29, 2010
    Assignee: Oryzon Genomics, S.A.
    Inventors: Tamara Maes, Carlos Buesa Arjol, Marta Barrachina Castillo, Isidro Ferrer Abizanda
  • Prognostic Methods in Colorectal Cancer
    Publication number: 20100035762
    Abstract: Prognostic method in colorectal cancer based on the determination of the expression levels of the EphB4 gene in tumours of patients afflicted by this disease. The levels can be used as a marker for the probability of the recurrence of the cancer in the patient and for the prognostics of the sensitivity that the tumours present to treatment with 5-fluorouracil, allowing to establish the more adequate therapeutic strategy for every patient.
    Type: Application
    Filed: June 21, 2007
    Publication date: February 11, 2010
    Applicant: Oryzon Genomics, S.A.
    Inventors: Simo Schwartz Navarro, Diego Arango del Corro, Lauri A. Aaltonen, John M. Mariadason, Carlos Buesa Arjol
  • Molecular Diagnostic Method and Treatment in Dementia With Lewy Bodies
    Publication number: 20090028845
    Abstract: The present invention describes methods of molecular diagnosis of a concrete form of a-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB.
    Type: Application
    Filed: July 18, 2005
    Publication date: January 29, 2009
    Applicant: Oryzon Genomics, S.A.
    Inventors: Tamara Maes, Carlos Buesa Arjol, Marta Barrachina Castillo, Isidro Ferrer Abizanda
  • Method for the analysis of differential expression in colorectal cancer
    Publication number: 20080286801
    Abstract: A method for the analysis of differential expression in colorectal cancer based on the variation in the expression levels of genes encoding for proteins forming part of the condensin complex or associated proteins that occurs in patients with the disease and that can be used as markers for the diagnosis of the cancers, as well as for the prevention and treatment thereof.
    Type: Application
    Filed: June 18, 2008
    Publication date: November 20, 2008
    Inventors: Carlos Buesa Arjol, Simo Schwartz Navarro, Diego Arango Del Corro