Abstract: Degradation of the reflectivity of one or more reflective optical elements in a system for generating EUV radiation is reduced by the controlled introduction of a gas into a vacuum chamber containing the optical element. The gas may be added to the flow of another gas such as hydrogen or alternated with the introduction of hydrogen radicals.

Abstract: This disclosure relates to a method and system for fast freezing of a biological product (such as blood plasma) contained in an individual bag or a plurality of bags. This disclosure relates to a method and system for freezing plasma in an individual bag or a plurality of bags, favoring bottom-up ice-growth, by implementing a differential air flow on top and bottom surfaces of a horizontally placed bag or bags filled with plasma. This disclosure relates to a method and a differential air flow system for freezing plasma, wherein the heat transfer coefficient on a bottom of a bag is at least 10 times larger than at a top. This disclosure relates to a differential air flow system and method for freezing plasma, wherein the differential air flow on top and bottom surfaces of a plasma bag is imposed by at least one fan or blower.

Abstract: A stapler includes a base, a magazine coupled to the base and configured to house staples, and a staple pusher assembly coupled with the magazine and operable to bias staples in the magazine toward a first end of the magazine where staples are driven out of the magazine. The staple pusher assembly includes a staple pusher defining a cavity, and a constant force spring having a first end coupled to the magazine and a second end that is coiled within the cavity in the staple pusher.

Abstract: There is described an apparatus for disinfecting a fluid, such as water. The apparatus includes a housing having a fluid inlet for inflow of a fluid to be disinfected, and a fluid outlet for outflow of the fluid to be disinfected. The apparatus further includes one or more light-emitting diodes (LEDs) operable to emit ultraviolet (UV) light for disinfecting the fluid to be disinfected. A fluid flow path extends from the fluid inlet to the fluid outlet. The fluid flow path is configured such that, when the fluid to be disinfected flows along the fluid flow path, the fluid to be disinfected flows sufficiently close to the one or more LEDs so as to absorb heat generated by the one or more LEDs.

Abstract: Provided are methods and devices for the label free detection of analytes in solution, including analytes suspended in a biological fluid. A field effect transistor (FET) is positioned in close proximity to a paired set of reference electrodes and the reference electrodes electrically biased to provide desalting and a stable gate voltage to the FET. In this manner, charged ions are depleted in the sensing region of the sensor and device sensitivity to analyte detection improved by the removal of charge that otherwise interferes with measurement. Also provided are methods and systems providing increased in reference electrode surface area and/or decrease in droplet volume to further improve label-free detection of analytes.

Abstract: A stapler includes a base, a magazine coupled to the base and configured to house staples, and a staple pusher assembly coupled with the magazine and operable to bias staples in the magazine toward a first end of the magazine where staples are driven out of the magazine. The staple pusher assembly includes a staple pusher defining a cavity, and a constant force spring having a first end coupled to the magazine and a second end that is coiled within the cavity in the staple pusher.

Abstract: Provided are methods and devices for the label free detection of analytes in solution, including analytes suspended in a biological fluid. A field effect transistor (FET) is positioned in close proximity to a paired set of reference electrodes and the reference electrodes electrically biased to provide desalting and a stable gate voltage to the FET. In this manner, charged ions are depleted in the sensing region of the sensor and device sensitivity to analyte detection improved by the removal of charge that otherwise interferes with measurement. Also provided are methods and systems providing increased in reference electrode surface area and/or decrease in droplet volume to further improve label-free detection of analytes.

Abstract: Provided are methods and devices for the label free detection of analytes in solution, including analytes suspended in a biological fluid. A field effect transistor (FET) is positioned in close proximity to a paired set of reference electrodes and the reference electrodes electrically biased to provide desalting and a stable gate voltage to the FET. In this manner, charged ions are depleted in the sensing region of the sensor and device sensitivity to analyte detection improved by the removal of charge that otherwise interferes with measurement. Also provided are methods and systems providing increased in reference electrode surface area and/or decrease in droplet volume to further improve label-free detection of analytes.

Abstract: The present invention regards a motorised system with electric traction with computer vision for outdoor environments, which can interact with the surrounding environment in an autonomous way or remotely operated. This vehicle tows a trailer that permits, amongst other functions, to perform golf balls picking.

Abstract: The invention relates to HIV chimeric gene formed by the union of fragments of different genes of said virus, wherein said fragments contains epitopes for cytotoxic T cells (CTL) or HIV-1 auxiliary T cells, which are presented by a wide range of antigens of type Major Histocompatibility Complex (HLA-I). Recombinant poxviruses are obtained from said genes, which are useful for prophylactic and therapeutic vaccination against HIV/AIDS infections, are capable of generating a protective immune cell response in vaccinated laboratory animals and are recognized by the CTL lymphocytes of HIV/AIDS patients.

Abstract: The invention relates to HIV chimeric gene formed by the union of fragments of different genes of said virus, wherein said fragments contains epitopes for cytotoxic T cells (CTL) or HIV-1 auxiliary T cells, which are presented by a wide range of antigens of type Major Histocompatibility Complex (HLA-I). Recombinant poxviruses are obtained from said genes, which are useful for prophylactic and therapeutic vaccination against HIV/AIDS infections, are capable of generating a protective immune cell response in vaccinated laboratory animals and are recognized by the CTL lymphocytes of HIV/AIDS patients.

Abstract: The present invention is related with the field of therapeutic vaccines against pathogens causing chronic diseases. It comprises the use in therapy of formulations containing the Hepatitis B surface antigen (HBsAg) as the main compound. The HBsAg is produced as a recombinant product in Picchia pastoris. The formulations of the present invention also comprise the combination of the Hepatitis B surface antigen and other coadministered antigens. The resulting formulations are able to generate potent lymphoprolipherative and cytotoxic responses apart from a remarkable response of specific antibodies, which make them very effective in the treatment of such diseases.

Abstract: A hinge assembly for coupling a spa cover to a spa, said spa cover being movable between a fully closed position and a fully open position. The hinge assembly includes a mounting bracket adapted to be installed near a top of the spa, and adapted to be coupled to a first end of a spring member; and a support arm pivotably coupled to the mounting bracket about an axis of rotation, adapted to be attached on an outside surface of the spa cover, and adapted to be coupled to a second end of the spring member. At least one of the mounting bracket or the support arm has a plurality of openings for selectively coupling the first end or the second end of the spring member, so as to adjust a coupling location between the spring member and the at least one of the mounting bracket or the support arm.

Abstract: A hinge assembly for coupling a spa cover to a spa includes a mounting bracket disposed near a top of the spa, a support arm which is pivotably coupled to the mounting bracket about an axis of rotation, and a spring member disposed between the mounting bracket and the support arm. The spa cover is movable between a fully closed position and a fully open position. The support arm is attached on an outside surface of the spa cover at a vertical offset from the axis of rotation when the spa cover is in the fully closed position. The spring member, which may be a gas spring, forms an angle of less than approximately 45 degrees with respect to the top of the spa when the spa cover is in the fully open position. A metal plate may be affixed using a double sided tape on an outside surface of the spa cover, and then anchored to the spa cover. The metal plate may be used to attach the support arm to the spa cover.

Abstract: A hinge assembly for coupling a spa cover to a spa includes a mounting bracket disposed near a top of the spa, a support arm which is pivotably coupled to the mounting bracket about an axis of rotation, and a spring member disposed between the mounting bracket and the support arm. The spa cover is movable between a fully closed position and a fully open position. The support arm is attached on an outside surface of the spa cover at a vertical offset from the axis of rotation when the spa cover is in the fully closed position. The spring member, which may be a gas spring, forms an angle of less than approximately 45 degrees with respect to the top of the spa when the spa cover is in the fully open position. A metal plate may be affixed using a double sided tape on an outside surface of the spa cover, and then anchored to the spa cover. The metal plate may be used to attach the support arm to the spa cover.

Abstract: A hinge assembly for coupling a spa cover to a spa includes a mounting bracket, a slide bracket and a support arm adapted to be attached to the spa cover. The mounting bracket is adapted to be installed near a top of the spa. The slide bracket is slidably coupled to the mounting bracket. The support arm is pivotably coupled to the slide bracket at a pivot point on the slide bracket. A metal plate may be affixed using a double sided tape on an outside surface of the spa cover, and then anchored to the spa cover. The metal plate may be used to attach the support arm to the spa cover.

Abstract: A hinge assembly for coupling a spa cover to a spa includes a mounting bracket disposed near a top of the spa, a support arm which is pivotably coupled to the mounting bracket about an axis of rotation, and a spring member disposed between the mounting bracket and the support arm. The spa cover is movable between a fully closed position and a fully open position. The support arm is attached on an outside surface of the spa cover at a vertical offset from the axis of rotation when the spa cover is in the fully closed position. The spring member, which may be a gas spring, forms an angle of less than approximately 45 degrees with respect to the top of the spa when the spa cover is in the fully open position. A metal plate may be affixed using a double sided tape on an outside surface of the spa cover, and then anchored to the spa cover. The metal plate may be used to attach the support arm to the spa cover.

Abstract: A hinge assembly for coupling a spa cover to a spa includes a mounting bracket, a slide bracket and a support arm adapted to be attached to the spa cover. The mounting bracket is adapted to be installed near a top of the spa. The slide bracket is slidably coupled to the mounting bracket. The support arm is pivotably coupled to the slide bracket at a pivot point on the slide bracket. A metal plate may be affixed using a double sided tape on an outside surface of the spa cover, and then anchored to the spa cover. The metal plate may be used to attach the support arm to the spa cover.

Abstract: The invention relates to HIV chimeric gene formed by the union of fragments of different genes of said virus, wherein said fragments contains epitopes for cytotoxic T cells (CTL) or HIV-1 auxiliary T cells, which are presented by a wide range of antigens of type Major Histocompatibility Complex (HLA-I). Recombinant poxviruses are obtained from said genes, which are useful for prophylactic and therapeutic vaccination against HIV/AIDS infections, are capable of generating a protective immune cell response in vaccinated laboratory animals and are recognized by the CTL lymphocytes of HIV/AIDS patients.

Abstract: A modified alumina is useful as metals passivator in fluidizable catalytic cracking catalysts. The modified alumina is prepared from a hydrated alumina, e.g., gibbsite, which is reacted with a low-molecular weight organic acid, e.g., acetic acid, forming aluminum salts. Calcination of the modified alumina results in decomposition of the aluminum salt.