Patents by Inventor Carlos G. Lopez Espina

Carlos G. Lopez Espina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240062885
    Abstract: A system for generating an interactive patient dashboard displaying metrics of a type of host response. The system may include processors and memory devices with instructions that configure the processors to perform operations. The operations may include transmitting a patient ID to a management platform or one or more devices (e.g., client devices), receiving electronic records, and employing a machine learning model to generate an acuity score based on the patient data. The operations may also include identifying critical parameters in the patient data by comparing parameters in the patient data with a distribution of parameters. The system can determine a ranking of the parameters, and generating a patient dashboard graphical user interface (GUI) for display. The dashboard GUI may include a prognostic indicator, and a list displaying the parameters according to the ranking.
    Type: Application
    Filed: January 12, 2022
    Publication date: February 22, 2024
    Inventors: Jonah ELLMAN, Carlos G. LOPEZ-ESPINA, Bobby REDDY, Jr., Akhil BHARGAVA, lshan TANEJA, Shah KHAN
  • Publication number: 20230368070
    Abstract: A system for adapting a machine learning model for a specific population. The system includes a processor and memory devices storing instructions that configure the memory devices to perform operations. The operations may include receive a local dataset comprising local records of patients associated with the healthcare facility, perform a clustering function, and retrieving a template dataset comprising template records organized in clusters with variable centroids. The operations may also include calculating a similarity metric between the local and template records, generating a synthetic dataset by combining template and local records, segregating the synthetic dataset into a training synthetic dataset and a testing synthetic dataset, and generating and/or validating a machine learning predictive model by tuning a template model according to the training synthetic dataset and/or generating a new predictive model.
    Type: Application
    Filed: October 1, 2021
    Publication date: November 16, 2023
    Inventors: Akhil BHARGAVA, Ishan TANEJA, Carlos G. LOPEZ-ESPINA, Bobby REDDY, Sihai Dave ZHAO, Ruoqing ZHU
  • Publication number: 20230042330
    Abstract: A method for ranking an unmeasured feature for an instance given at least one feature is measured is provided. The method includes imputing a first value to the unmeasured feature in the instance while holding the other remaining unmeasured features constant and evaluating a first outcome with a model using the first value in the instance. The method includes imputing a second value to the unmeasured feature in the dataset while holding the other remaining unmeasured features constant, evaluating a second outcome with the model using the second value in the instance, and determining a statistical parameter with the first outcome and the second outcome. The method also includes assigning the unmeasured feature a ranking corresponding to the determined statistical parameter. A system and a non-transitory, computer readable medium storing instructions to perform the above method are also presented.
    Type: Application
    Filed: January 12, 2021
    Publication date: February 9, 2023
    Inventors: Ishan Taneja, Carlos G. Lopez-Espina, Sihai Dave Zhao, Ruoqing Zhu, Bobby Reddy, JR.
  • Publication number: 20230040185
    Abstract: A method for making dynamic risk predictions is provided. The method includes receiving a dataset with a first data field and a second data field. The first data field is populated with a measured value. The method also includes imputing a first predicted value to the second data field, generating a first risk score and a first set of associated metrics based on the measured value and the first predicted value, and imputing a second predicted value to the second data field. The method also includes calculating a statistically derived metric and determining whether the statistically derived metric exceeds a predetermined threshold, wherein a predetermined action is recommended if the statistically derived metric exceeds the predetermined threshold. A system and a non-transitory, computer readable medium storing instructions to cause the system to perform the above method are also provided.
    Type: Application
    Filed: January 12, 2021
    Publication date: February 9, 2023
    Inventors: Ishan Taneja, Carlos G. Lopez-Espina, Sihai Dave Zhao, Ruoqing Zhu, Bobby Reddy, Jr.
  • Publication number: 20220347677
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Application
    Filed: June 30, 2022
    Publication date: November 3, 2022
    Applicant: Haemonetics Corporation
    Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Patent number: 11406978
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: August 9, 2022
    Assignee: Haemonetics Corporation
    Inventors: Peter Delemico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Publication number: 20190283020
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Application
    Filed: June 7, 2019
    Publication date: September 19, 2019
    Applicant: Cormed Technologies, LLC
    Inventors: Peter Delemico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Patent number: 10357769
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: July 23, 2019
    Assignee: Coramed Technologies, LLC
    Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Publication number: 20170189903
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Application
    Filed: March 21, 2017
    Publication date: July 6, 2017
    Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Patent number: 9599601
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: March 21, 2017
    Assignee: CORAMED TECHNOLOGIES LLC
    Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Patent number: 9575078
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: February 21, 2017
    Assignee: Coramed Technologies, LLC
    Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Publication number: 20150316534
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Application
    Filed: June 29, 2015
    Publication date: November 5, 2015
    Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Publication number: 20150260735
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 17, 2015
    Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Patent number: 9068966
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 30, 2015
    Assignee: Coramed Technologies, LLC
    Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Publication number: 20140328732
    Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
    Type: Application
    Filed: March 14, 2014
    Publication date: November 6, 2014
    Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
  • Patent number: 8141437
    Abstract: A system monitors dynamic forces between bearing surfaces. Based on sensed data, the system may model the forces on the bearing surfaces, analyze these forces, store data relating to these forces, and/or transmit data to an external data gathering device. The system includes a first body piece and a second body piece which mate together. The first and second body pieces comprise bearing surfaces that contact a material that may exert a force. A protrusion, such as a pole, post, or beam, extends from first body piece's bearing surface. At least one sensor is disposed on a pole. The at least one sensor detects a mechanical motion of the pole resulting from a force imposed on the body pieces, and generates data indicative of this force. A computer communicates with the at least one sensor and processes the sensed and/or modeled data.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: March 27, 2012
    Assignee: Ortho Sensing Technologies, LLC
    Inventors: Farid Amirouche, Carlos G. Lopez Espina