Patents by Inventor Carlos G. Lopez Espina
Carlos G. Lopez Espina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240062885Abstract: A system for generating an interactive patient dashboard displaying metrics of a type of host response. The system may include processors and memory devices with instructions that configure the processors to perform operations. The operations may include transmitting a patient ID to a management platform or one or more devices (e.g., client devices), receiving electronic records, and employing a machine learning model to generate an acuity score based on the patient data. The operations may also include identifying critical parameters in the patient data by comparing parameters in the patient data with a distribution of parameters. The system can determine a ranking of the parameters, and generating a patient dashboard graphical user interface (GUI) for display. The dashboard GUI may include a prognostic indicator, and a list displaying the parameters according to the ranking.Type: ApplicationFiled: January 12, 2022Publication date: February 22, 2024Inventors: Jonah ELLMAN, Carlos G. LOPEZ-ESPINA, Bobby REDDY, Jr., Akhil BHARGAVA, lshan TANEJA, Shah KHAN
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Publication number: 20230368070Abstract: A system for adapting a machine learning model for a specific population. The system includes a processor and memory devices storing instructions that configure the memory devices to perform operations. The operations may include receive a local dataset comprising local records of patients associated with the healthcare facility, perform a clustering function, and retrieving a template dataset comprising template records organized in clusters with variable centroids. The operations may also include calculating a similarity metric between the local and template records, generating a synthetic dataset by combining template and local records, segregating the synthetic dataset into a training synthetic dataset and a testing synthetic dataset, and generating and/or validating a machine learning predictive model by tuning a template model according to the training synthetic dataset and/or generating a new predictive model.Type: ApplicationFiled: October 1, 2021Publication date: November 16, 2023Inventors: Akhil BHARGAVA, Ishan TANEJA, Carlos G. LOPEZ-ESPINA, Bobby REDDY, Sihai Dave ZHAO, Ruoqing ZHU
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Publication number: 20230042330Abstract: A method for ranking an unmeasured feature for an instance given at least one feature is measured is provided. The method includes imputing a first value to the unmeasured feature in the instance while holding the other remaining unmeasured features constant and evaluating a first outcome with a model using the first value in the instance. The method includes imputing a second value to the unmeasured feature in the dataset while holding the other remaining unmeasured features constant, evaluating a second outcome with the model using the second value in the instance, and determining a statistical parameter with the first outcome and the second outcome. The method also includes assigning the unmeasured feature a ranking corresponding to the determined statistical parameter. A system and a non-transitory, computer readable medium storing instructions to perform the above method are also presented.Type: ApplicationFiled: January 12, 2021Publication date: February 9, 2023Inventors: Ishan Taneja, Carlos G. Lopez-Espina, Sihai Dave Zhao, Ruoqing Zhu, Bobby Reddy, JR.
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Publication number: 20230040185Abstract: A method for making dynamic risk predictions is provided. The method includes receiving a dataset with a first data field and a second data field. The first data field is populated with a measured value. The method also includes imputing a first predicted value to the second data field, generating a first risk score and a first set of associated metrics based on the measured value and the first predicted value, and imputing a second predicted value to the second data field. The method also includes calculating a statistically derived metric and determining whether the statistically derived metric exceeds a predetermined threshold, wherein a predetermined action is recommended if the statistically derived metric exceeds the predetermined threshold. A system and a non-transitory, computer readable medium storing instructions to cause the system to perform the above method are also provided.Type: ApplicationFiled: January 12, 2021Publication date: February 9, 2023Inventors: Ishan Taneja, Carlos G. Lopez-Espina, Sihai Dave Zhao, Ruoqing Zhu, Bobby Reddy, Jr.
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Publication number: 20220347677Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: ApplicationFiled: June 30, 2022Publication date: November 3, 2022Applicant: Haemonetics CorporationInventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
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Patent number: 11406978Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: GrantFiled: June 7, 2019Date of Patent: August 9, 2022Assignee: Haemonetics CorporationInventors: Peter Delemico, Carlos G. Lopez-Espina, Gabriel Raviv
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Publication number: 20190283020Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: ApplicationFiled: June 7, 2019Publication date: September 19, 2019Applicant: Cormed Technologies, LLCInventors: Peter Delemico, Carlos G. Lopez-Espina, Gabriel Raviv
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Patent number: 10357769Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: GrantFiled: March 21, 2017Date of Patent: July 23, 2019Assignee: Coramed Technologies, LLCInventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
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Publication number: 20170189903Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: ApplicationFiled: March 21, 2017Publication date: July 6, 2017Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
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Patent number: 9599601Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: GrantFiled: June 29, 2015Date of Patent: March 21, 2017Assignee: CORAMED TECHNOLOGIES LLCInventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
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Patent number: 9575078Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: GrantFiled: March 14, 2014Date of Patent: February 21, 2017Assignee: Coramed Technologies, LLCInventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
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Publication number: 20150316534Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: ApplicationFiled: June 29, 2015Publication date: November 5, 2015Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
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Publication number: 20150260735Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: ApplicationFiled: March 14, 2014Publication date: September 17, 2015Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
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Patent number: 9068966Abstract: A sample testing cartridge is usable to perform a variety of tests on a viscoelastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: GrantFiled: March 14, 2014Date of Patent: June 30, 2015Assignee: Coramed Technologies, LLCInventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
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Publication number: 20140328732Abstract: A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.Type: ApplicationFiled: March 14, 2014Publication date: November 6, 2014Inventors: Peter Delmenico, Carlos G. Lopez-Espina, Gabriel Raviv
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Patent number: 8141437Abstract: A system monitors dynamic forces between bearing surfaces. Based on sensed data, the system may model the forces on the bearing surfaces, analyze these forces, store data relating to these forces, and/or transmit data to an external data gathering device. The system includes a first body piece and a second body piece which mate together. The first and second body pieces comprise bearing surfaces that contact a material that may exert a force. A protrusion, such as a pole, post, or beam, extends from first body piece's bearing surface. At least one sensor is disposed on a pole. The at least one sensor detects a mechanical motion of the pole resulting from a force imposed on the body pieces, and generates data indicative of this force. A computer communicates with the at least one sensor and processes the sensed and/or modeled data.Type: GrantFiled: March 29, 2006Date of Patent: March 27, 2012Assignee: Ortho Sensing Technologies, LLCInventors: Farid Amirouche, Carlos G. Lopez Espina