Patents by Inventor Carlos G. Nascimento

Carlos G. Nascimento has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human epidermal growth factor having substitution at position 11
    Patent number: 5158935
    Abstract: We have now found that one may improve the storage life of EGF without diminishing its biological activity by replacing the Asp at position 11 with a different amino acid, preferably Glu, Asn, Gln, Ala, or Lys, more preferably Glu, or Asn, and most preferably Glu. Other modifications may additionally be made, most preferably by substituting Met.sub.21 (which we have found is susceptible to oxidation) with Ile or a similar amino acid.
    Type: Grant
    Filed: May 12, 1989
    Date of Patent: October 27, 1992
    Assignee: Chiron Corporation
    Inventors: Carlos G. Nascimento, Angelica Medina-Selby