Patents by Inventor Carlotta Petticone

Carlotta Petticone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing T cells with increased activity
    Patent number: 11903967
    Abstract: The present invention provides a method of preparing a population of genetically modified cells which comprise a chimeric antigen receptor (CAR) or a transgenic T-cell receptor (TCR) comprising: providing a starting population of cells; depleting said starting population of cells which express a target antigen; and introducing into a cell in the depleted starting population a nucleic acid sequence which encodes a CAR or transgenic TCR against the target antigen. The present invention also provides genetically modified cells, pharmaceutical compositions and pharmaceutical compositions for use in the treatment and/or prevention of disease.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: February 20, 2024
    Assignee: AUTOLUS LIMITED
    Inventors: Martin Pulé, Carlotta Petticone, James Faulkner, Ekaterini Kotsopoulou, Emma Chan, Richard Beswick
  • Method
    Publication number: 20190209612
    Abstract: The present invention provides a method of preparing a population of genetically modified cells which comprise a chimeric antigen receptor (CAR) or a transgenic T-cell receptor (TCR) comprising: providing a starting population of cells; depleting said starting population of cells which express a target antigen; and introducing into a cell in the depleted starting population a nucleic acid sequence which encodes a CAR or transgenic TCR against the target antigen. The present invention also provides genetically modified cells, pharmaceutical compositions and pharmaceutical compositions for use in the treatment and/or prevention of disease.
    Type: Application
    Filed: November 12, 2018
    Publication date: July 11, 2019
    Inventors: Martin Pulé, Carlotta Petticone, James Faulkner, Ekaterini Kotsopoulou, Emma Chan, Richard Beswick