Patents by Inventor Carol A. Rae

Carol A. Rae has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC COMPOSITIONS FOR VIRAL-ASSOCIATED DISEASE STATES AND METHODS OF MAKING AND USING SAME
    Publication number: 20240165314
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Application
    Filed: December 26, 2023
    Publication date: May 23, 2024
    Applicant: Immutrix Therapeutics, Inc.
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • THERAPEUTIC DETOXIFICATION COMPOSITIONS AND METHODS OF MAKING AND USING SAME
    Publication number: 20240100090
    Abstract: A three component composition for use in the treatment of an autoimmune disease where the first component comprises a bimodal synthetic carbon particle mixture; the second component comprises a bimodal synthetic carbon particle mixture and an anion exchange resin and the third component comprises a bimodal synthetic carbon particle mixture and a cation exchange resin.
    Type: Application
    Filed: October 30, 2023
    Publication date: March 28, 2024
    Applicant: Immutrix Therapeutics, Inc.
    Inventors: Carol A Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Therapeutic compositions for viral-associated disease states and methods of making and using same
    Patent number: 11918728
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: March 5, 2024
    Assignee: Immutrix Therapeutics, Inc.
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller, Jose A. Diaz-Aunon
  • Therapeutic compositions for viral-associated disease states and methods of making and using same
    Patent number: 11896753
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: February 13, 2024
    Assignee: Immutrix Therapeutics, Inc.
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Therapeutic detoxification compositions and methods of making and using same
    Patent number: 11839628
    Abstract: A three component composition for use in the treatment of an autoimmune disease where the first component comprises a bimodal synthetic carbon particle mixture; the second component comprises a bimodal synthetic carbon particle mixture and an anion exchange resin and the third component comprises a bimodal synthetic carbon particle mixture and a cation exchange resin.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: December 12, 2023
    Assignee: Immutrix Therapeutics, Inc.
    Inventors: Carol A Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • THERAPEUTIC COMPOSITIONS FOR VIRAL-ASSOCIATED DISEASE STATES AND METHODS OF MAKING AND USING SAME
    Publication number: 20230372596
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is in a range from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is in a range from about 0.1:100 to 100:0.1 to produce a third filtrate.
    Type: Application
    Filed: August 3, 2023
    Publication date: November 23, 2023
    Applicant: Immutrix Therapeutics, Inc.
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Therapeutic compositions for viral-associated disease states and methods of making and using same
    Patent number: 11759561
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Grant
    Filed: September 1, 2020
    Date of Patent: September 19, 2023
    Assignee: Immutrix Therapeutics, Inc.
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • UNIVERSAL BLOOD PRODUCT AND METHODS OF PREPARING AND USING SAME
    Publication number: 20220152524
    Abstract: A method of preparing a universal blood product comprising obtaining a blood product; contacting the blood product with (i) hydroxyapatite; (ii) a carbonaceous material comprising at least a mixture of a first carbon particle having macroporous size ? and a second carbon particle having macroporous size ?; and (iii) at least one support matrix chemically associated with an antigenic determinant.to form a cleansed product; and recovering the cleansed product.
    Type: Application
    Filed: January 6, 2022
    Publication date: May 19, 2022
    Applicant: Proprietary Technology Assets, LLC
    Inventors: Carol A. Rae, Jan S. Simoni, John F. Moeller
  • Universal blood product and methods of preparing and using same
    Patent number: 11253794
    Abstract: A method of preparing a universal blood product comprising obtaining a blood product; contacting the blood product with (i) hydroxyapatite; (ii) a carbonaceous material comprising at least a mixture of a first carbon particle having macroporous size ? and a second carbon particle having macroporous size ?; and (iii) at least one support matrix chemically associated with an antigenic determinant. to form a cleansed product; and recovering the cleansed product. A method of preparing a universal blood product comprising obtaining a blood product; contacting the blood product with (i) hydroxyapatite; (ii) a carbonaceous material comprising at least a mixture of a first carbon particle having macroporous size ? and a second carbon particle having macroporous size ?; and (iii) at least one support matrix chemically associated with an antigenic determinant. to form a cleansed product; wherein at least one of the hydroxyapatite, carbonaceous material and support matrix is functionalized.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: February 22, 2022
    Assignee: Proprietary Technology Assets, LLC
    Inventors: Carol A. Rae, Jan S. Simoni, John F. Moeller
  • Therapeutic Detoxification Compositions and Methods of Making and Using Same
    Publication number: 20210236543
    Abstract: A three component composition for use in the treatment of an autoimmune disease where the first component comprises a bimodal synthetic carbon particle mixture; the second component comprises a bimodal synthetic carbon particle mixture and an anion exchange resin and the third component comprises a bimodal synthetic carbon particle mixture and a cation exchange resin.
    Type: Application
    Filed: March 26, 2021
    Publication date: August 5, 2021
    Applicant: IMMUTRIX THERAPEUTICS, INC.
    Inventors: Carol A Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Therapeutic detoxification compositions and methods of making and using same
    Patent number: 10960022
    Abstract: A three component composition for use in the treatment of an autoimmune disease where the first component comprises a bimodal synthetic carbon particle mixture; the second component comprises a bimodal synthetic carbon particle mixture and an anion exchange resin and the third component comprises a bimodal synthetic carbon particle mixture and a cation exchange resin.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: March 30, 2021
    Assignee: Immutrix Therapeutics, Inc.
    Inventors: Carol A Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • THERAPEUTIC COMPOSITIONS FOR VIRAL-ASSOCIATED DISEASE STATES AND METHODS OF MAKING AND USING SAME
    Publication number: 20210052803
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Application
    Filed: November 6, 2020
    Publication date: February 25, 2021
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller, Jose A. Diaz-Aunon
  • THERAPEUTIC COMPOSITIONS FOR VIRAL-ASSOCIATED DISEASE STATES AND METHODS OF MAKING AND USING SAME
    Publication number: 20200397973
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Application
    Filed: September 1, 2020
    Publication date: December 24, 2020
    Applicant: ImMutriX Therapeutics, Inc.
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Therapeutic compositions for viral-associated disease states and methods of making and using same
    Patent number: 10773011
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: September 15, 2020
    Assignee: Immutrix Therapeutics, Inc.
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Therapeutic Compositions for Viral-Associated Disease States and Methods of Making and Using Same
    Publication number: 20200197598
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Application
    Filed: March 3, 2020
    Publication date: June 25, 2020
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Therapeutic compositions for viral-associated disease states and methods of making and using same
    Patent number: 10617813
    Abstract: A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: April 14, 2020
    Assignee: IMMUTRIX THERAPEUTICS, INC.
    Inventors: Carol A. Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • METHOD FOR EXTRACORPOREAL TREATMENT OF PREECLAMPSIA AND RELATED DISORDERS
    Publication number: 20190105631
    Abstract: A three-component composition for use in the treatment of preeclampsia and related disorders wherein a first component comprises a bimodal synthetic carbon particle mixture; a second component comprises a resin bead with at least one affinity ligand directed toward syncytiotrophoblast-derived factor sEndoglin and a third component comprises a resin bead with at least one affinity ligand directed toward syncytiotrophoblast-derived factor soluble Fms-like tyrosine kinase-1.
    Type: Application
    Filed: March 31, 2017
    Publication date: April 11, 2019
    Inventors: Carol A. Rae, Jan Simoni, John F. Moeller
  • Therapeutic Detoxification Compositions and Methods of Making and Using Same
    Publication number: 20190046567
    Abstract: A three component composition for use in the treatment of an autoimmune disease where the first component comprises a bimodal synthetic carbon particle mixture; the second component comprises a bimodal synthetic carbon particle mixture and an anion exchange resin and the third component comprises a bimodal synthetic carbon particle mixture and a cation exchange resin.
    Type: Application
    Filed: October 16, 2018
    Publication date: February 14, 2019
    Inventors: Carol A Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • Therapeutic detoxification compositions and methods of making and using same
    Patent number: 10137151
    Abstract: A three component composition for use in the treatment of an autoimmune disease where the first component comprises a bimodal synthetic carbon particle mixture; the second component comprises a bimodal synthetic carbon particle mixture and an anion exchange resin and the third component comprises a bimodal synthetic carbon particle mixture and a cation exchange resin.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: November 27, 2018
    Assignee: IMMUTRIX THERAPEUTICS, INC.
    Inventors: Carol A Rae, Jan Simoni, Grace Simoni, John F. Moeller
  • UNIVERSAL BLOOD PRODUCT AND METHODS OF PREPARING AND USING SAME
    Publication number: 20180065062
    Abstract: A method of preparing a universal blood product comprising obtaining a blood product; contacting the blood product with (i) hydroxyapatite; (ii) a carbonaceous material comprising at least a mixture of a first carbon particle having macroporous size ? and a second carbon particle having macroporous size ?; and (iii) at least one support matrix chemically associated with an antigenic determinant.to form a cleansed product; and recovering the cleansed product. A method of preparing a universal blood product comprising obtaining a blood product; contacting the blood product with (i) hydroxyapatite; (ii) a carbonaceous material comprising at least a mixture of a first carbon particle having macroporous size ? and a second carbon particle having macroporous size ?; and (iii) at least one support matrix chemically associated with an antigenic determinant.to form a cleansed product; wherein at least one of the hydroxyapatite, carbonaceous material and support matrix is functionalized.
    Type: Application
    Filed: May 27, 2016
    Publication date: March 8, 2018
    Inventors: Carol A. Rae, Jan S. Simoni, John F. Moeller