Abstract: A method for the acceptance testing of a set of multiple colored workpieces (e.g., paired color pads of a calibrated color chart or paired membranes of visual blood glucose test strip). The method includes first measuring a plurality of color parameters (e.g., L*a*b* color parameters) associated with the set of multiple colored workpieces, followed by conversion of the plurality of color parameters into a single response parameter. Next, the single response parameter for the set is compared to a predetermined single response parameter specification for the set and acceptance of the set of multiple colored workpieces determined based on the comparison. The method can be easily employed in conjunction with multiple (e.g., paired) membrane test strips used to measure, for example, glucose, cholesterol, proteins, ketones, phenylalanine or enzymes in blood, urine, saliva or other biological fluid and/or sample fluid characteristics such as pH and alkalinity.