Patents by Inventor Carola Schroeder

Carola Schroeder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serum-free stable transfection and production of recombinant human proteins in human cell lines
    Patent number: 9796986
    Abstract: The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: October 24, 2017
    Assignee: OCTAPHARMA AG
    Inventors: Carola Schroeder, Haiyan Ding, Cathleen Wegmann
  • SERUM-FREE STABLE TRANSFECTION AND PRODUCTION OF RECOMBINANT HUMAN PROTEINS IN HUMAN CELL LINES
    Publication number: 20170152523
    Abstract: The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 1, 2017
    Applicant: Octapharma AG
    Inventors: Carola Schroeder, Haiyan Ding, Cathleen Wegmann
  • Serum-free stable transfection and production of recombinant human proteins in human cell lines
    Patent number: 9512457
    Abstract: The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: December 6, 2016
    Assignee: OCTAPHARMA AG
    Inventors: Carola Schroeder, Haiyan Ding, Cathleen Wegmann
  • Serum-free Stable Transfection and Production of Recombinant Human Proteins in Human Cell Lines
    Publication number: 20160177362
    Abstract: The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.
    Type: Application
    Filed: February 1, 2016
    Publication date: June 23, 2016
    Applicant: Octapharma AG
    Inventors: Carola Schroeder, Haiyan Ding, Cathleen Wegmann
  • Serum-free stable transfection and production of recombinant human proteins in human cell lines
    Patent number: 9273325
    Abstract: The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: March 1, 2016
    Inventors: Carola Schroeder, Haiyan Ding, Cathleen Wegmann
  • Recombinantly produced human factor VIII and IX
    Patent number: 9120873
    Abstract: A recombinant human factor VIII or IX protein having a human glycosylation pattern but the protein is devoid of N-glycolylneuraminic acid and/or the carbohydrate group Gal?-3Gal.
    Type: Grant
    Filed: August 21, 2009
    Date of Patent: September 1, 2015
    Assignee: Octapharma AG
    Inventors: Helena Sandberg, Peter Stenlund, Carola Schröder, Elisabeth Casademunt, Maya Tiemeyer
  • SERUM-FREE STABLE TRANSFECTION AND PRODUCTION OF RECOMBINANT HUMAN PROTEINS IN HUMAN CELL LINES
    Publication number: 20150044720
    Abstract: The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.
    Type: Application
    Filed: October 3, 2014
    Publication date: February 12, 2015
    Applicant: Octapharma AG
    Inventors: Carola Schroeder, Haiyan Ding, Cathleen Wegmann
  • Serum-free stable transfection and production of recombinant human proteins in human cell lines
    Patent number: 8871439
    Abstract: The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: October 28, 2014
    Assignee: Octapharma AG
    Inventors: Carola Schroeder, Haiyan Ding, Cathleen Wegmann
  • Processing of recombinant human G-CSF precursor
    Patent number: 8436142
    Abstract: A G-CSF precursor comprising a signal peptide and a G-CSF peptide, wherein the signal peptide has the sequence of the human wild-type signal peptide of the human G-CSF/b molecule with at least one of the following mutations: deletion of Glu29, insertion of Glu26, substitution Lys11Leu, substitution His21Phe, and substitution Gln28Leu.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: May 7, 2013
    Assignee: Octapharma AG
    Inventors: Carola Schröder, Elisabeth Casademunt, Peter Söhlemann, Michael Lehnerer
  • PROCESSING OF RECOMBINANT HUMAN G-CSF
    Publication number: 20110294989
    Abstract: A G-CSF precursor comprising a signal peptide and a G-CSF peptide, wherein the signal peptide has the sequence of the human wild-type signal peptide of the human G-CSF/b molecule with at least one of the following mutations: deletion of Glu29, insertion of Glu26, substitution Lys11Leu, substitution His21Phe, and substitution Glu28Leu.
    Type: Application
    Filed: October 2, 2009
    Publication date: December 1, 2011
    Applicant: OCTOPHARMA BIOPHARMACEUTICALS GMBH
    Inventors: Carola Schröder, Elisabeth Casademunt, Peter Söhlemann, Michael Lehnerer
  • RECOMBINANTLY PRODUCED HUMAN FACTOR VIII AND IX
    Publication number: 20110262424
    Abstract: A recombinant human factor VIII or IX protein having a human glycosylation pattern but the protein is devoid of N-glycolylneuraminic acid and/or the carbohydrate group Gal?-3Gal.
    Type: Application
    Filed: August 21, 2009
    Publication date: October 27, 2011
    Inventors: Helena Sandberg, Peter Stenlund, Carola Schröder, Elisabeth Casademunt, Maya Tiemeyer
  • Serum-free Stable Transfection and Production of Recombinant Human Proteins in Human Cell Lines
    Publication number: 20100184141
    Abstract: The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.
    Type: Application
    Filed: June 29, 2006
    Publication date: July 22, 2010
    Applicant: OCTAPHARMA AG
    Inventors: Carola Schroeder, Haiyan Ding, Cathleen Wegmann
  • Recombinant blood clotting factors
    Patent number: 7572619
    Abstract: The present invention relates to an improved method for the production of recombinant human blood clotting factors, in particular of factor VIII and factor IX. An immortalized human cell line can be used to stably express viral transcription activator proteins and carrying a vector having a promoter functionally linked to a DNA sequence coding for a blood coagulating factor, provided that said promoter is not a viral promoter which is stimulated by said viral transcription activator proteins. The invention further relates to an immortalized human cell line carrying said vector, factor VIII muteins particularly suitable for the above production method; pharmaceutical compositions comprising such factor VIII muteins, and the use of such factor VIII muteins for preparing a medicament for treating hemophilia.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: August 11, 2009
    Assignee: Octagene GmbH
    Inventors: Charlotte Hauser, Andrea Hörster, Carola Schröder, Michael Lehnerer