Patents by Inventor Caroline Jane Day

Caroline Jane Day has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-infammatory macrolide
    Patent number: 8227428
    Abstract: The compound 3?-N-demethyl-4?-O-(2-diethylaminoethanoyl)-6-O-methyl-9a-aza-9a-homoerythromycin A, having the Formula (I): or a salt thereof, compositions comprising the compound, its use in the treatment of neutrophil dominated inflammatory diseases, and methods for its preparation.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: July 24, 2012
    Assignee: Glaxo Group Limited
    Inventors: Caroline Jane Day, Julien Bruno Douillet, Darko Filic, Leanda Jane Kindon, Goran Kragol, Zorica Marusic-Istuk
  • Pyrazolo[3,4-b]pyridine compounds, and their use as PDE4 inhibitors
    Patent number: 8003663
    Abstract: The invention provides N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo [3,4-b]pyridin-5-yl]methyl}-4-({8-[(2-hydroxyethyl) (methyl)amino]octanoyl}amino)benzamide, whose formula is or a salt thereof, such as the monohydrochloride salt thereof. The invention also provides the use of the compound or salt as inhibitors of phosphodiesterase type IV (PDE4) and/or for the treatment and/or prophylaxis of inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, or rhinitis (e.g. allergic and/or non-allergic rhinitis).
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: August 23, 2011
    Assignee: Glaxo Group Limited
    Inventors: David George Allen, Rodger Phillip Barnett, Reshma Manesh Chudasama, Caroline Jane Day, Christopher David Edlin, Leanda Jane Kindon
  • SALT OF, AND PROCESSES FOR THE PREPARATION OF, 1-ISOPROPYL-4-HEXAHYDRO-1H-1,4-DIAZEPINE
    Publication number: 20110190274
    Abstract: The invention relates to 1-isopropyl-4-{[4-(tetrahydro-2H-pyran-4-yloxy)phenyl]carbonyl}hexahydro-1H-1,4-diazepine mono-maleate, and crystalline Form 1 thereof.
    Type: Application
    Filed: August 14, 2009
    Publication date: August 4, 2011
    Inventors: Caroline Jane Day, Trevor Raymond Keel, Geracimos Rassias
  • HEMI-FUMARATE SALT OF A 1,3,4-THIADIAZOLYL DERIVATIVE AS MODULATOR OF THE SPHINGOSINE 1-PHOSPHATE RECEPTOR
    Publication number: 20110034524
    Abstract: The invention relates to the compound (2S)-2-amino-2-{5-[4-(octyloxy)-3-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl}-1-propanol hemi-fumarate, processes for its preparation, pharmaceutical compositions containing them and its use in the treatment of conditions or disorders which are mediated via the S1P1 receptor.
    Type: Application
    Filed: February 3, 2009
    Publication date: February 10, 2011
    Applicant: Glaxo Group Limited
    Inventors: Michael Simon Anson, Caroline Jane Day, Jonathan Paul Graham, Leanda Jane Kindon, Grahame Robert Woollam
  • Anti-Infammatory Macrolide
    Publication number: 20100197623
    Abstract: The compound 3?-N-demethyl-4?-O-(2-diethylaminoethanoyl)-6-O-methyl-9a-aza-9a-homoerythromycin A, having the Formula (I): or a salt thereof, compositions comprising the compound, its use in the treatment of neutrophil dominated inflammatory diseases, and methods for its preparation.
    Type: Application
    Filed: January 28, 2010
    Publication date: August 5, 2010
    Inventors: Caroline Jane Day, Julien Bruno Douillet, Darko Filic, Leanda Jane Kindon, Goran Kragol, Zorica Marusic-Istuk
  • PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS
    Publication number: 20090325952
    Abstract: The invention provides a compound of formula (I) or a salt thereof: wherein Ar has the sub-formula (x): as defined herein, and the use of the compounds as inhibitors of PDE4.
    Type: Application
    Filed: July 31, 2007
    Publication date: December 31, 2009
    Inventors: David George Allen, Nicola Mary Aston, Rodger Phillip Barnett, Reshma Manesh Chudasama, Caroline Jane Day, Christopher David Edlin, Leanda Jane Kindon, Naimisha Trivedi
  • 1-Benzazepine-3-Sulfonylamino-2-Pyrroridones as Factor Xa Inhibitors
    Publication number: 20080306045
    Abstract: The invention relates to chemical entities of formula (I): and/or pharmaceutically acceptable derivative(s) thereof. The invention also relates to processes for the preparation of compounds of formula (I), pharmaceutical compositions containing compounds of formula (I) and to the use of compounds of formula (I) in medicine, particularly in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
    Type: Application
    Filed: November 22, 2006
    Publication date: December 11, 2008
    Inventors: Laure Camus, Reshma Chudasama, Caroline Jane Day, Deepali Deshmukh, John Gerald Gleason, John David Harling, Chao-Pin Lee, Paula Saklatvala, Stefan Senger, Sarah Vallance, John Watson, Nigel Stephen Watson, Robert John Young, Barbara Yuan
  • Process for preparing a thiazole PPAR-ligand and polymorphs thereof
    Patent number: 7244849
    Abstract: A method of preparing a compound of formula (I), and pharmaceutically acceptable salts and solvates thereof.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: July 17, 2007
    Assignee: Glaxo Group Limited
    Inventors: Thierry Boyer, Caroline Jane Day, Andrew Jonathan Whitehead, Richard Anthony Henson
  • Process for preparinga thiazole ppar-ligand and polymorphs thereof
    Publication number: 20040242657
    Abstract: A method of preparing a compound of formula (I), and pharmaceutically acceptable salts and solvates thereof. Polymorphs of this compound and their use as PPAR ligands are also disclosed.
    Type: Application
    Filed: April 27, 2004
    Publication date: December 2, 2004
    Inventors: Thierry Boyer, Caroline Jane Day, Andrew Jonathan Whitehead, Richard Anthony Henson