Abstract: An electronic patient handoff system and method provides a common interface for different types of healthcare providers, further customized in selection and arrangement of factors for risk mitigation. Upon initiation of patient handoff among healthcare providers, the system accesses patient data records and generates a customized patient data interface based at least on provider attributes, patient attributes and factor attributes (e.g., abnormality). The caregiver can provide feedback regarding selection and arrangement of factors in the interface, wherein the system may selectively apply the received feedback in subsequent patient handoff iterations. Potential areas of concern are listed based on provider feedback, patient-matched areas of concern, and predicted quality-adjusted life-year (QALY) impact.