Patents by Inventor Carolyn E. Mountford

Carolyn E. Mountford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190125257
    Abstract: A system and method identifies Post Traumatic Stress Disorder by the use of magnetic resonance spectroscopy (MRS) to measure absolute and relative concentrations of metabolites in specific brain regions in the central nervous system or brain. The system and method can be used as a diagnostic tool for the assessment of PTSD. These chemical changes in the brain of those people suffering from PTSD are different from those suffering from head injury, chronic pain and other neurological conditions.
    Type: Application
    Filed: September 12, 2016
    Publication date: May 2, 2019
    Applicant: Translational Research Institute
    Inventors: Carolyn E. Mountford, Scott Quadrelli
  • Publication number: 20130245957
    Abstract: Robust classification methods analyse magnetic resonance spectroscopy (MRS) data (spectra) of fine needle aspirates taken from breast tumours. The resultant data when compared with the histopathology and clinical criteria provide computerized classification-based diagnosis and prognosis with a very high degree of accuracy and reliability. Diagnostic correlation performed between the spectra and standard synoptic pathology findings contain detail regarding the pathology (malignant versus benign), vascular invasion by the primary cancer and lymph node involvement of the excised axillary lymph nodes. The classification strategy consisted of three stages: pre-processing of MR magnitude spectra to identify optimal spectral regions, cross-validated Linear Discriminant Analysis, and classification aggregation via Computerised Consensus Diagnosis. Malignant tissue was distinguished from benign lesions with an overall accuracy of 93%.
    Type: Application
    Filed: February 28, 2013
    Publication date: September 19, 2013
    Inventors: Carolyn E. Mountford, Peter Russell, Ian C.P. Smith, Rajmund L. Somorjai
  • Patent number: 8404487
    Abstract: Robust classification methods analyse magnetic resonance spectroscopy (MRS) data (spectra) of fine needle aspirates taken from breast tumors. The resultant data when compared with the histopathology and clinical criteria provide computerized classification-based diagnosis and prognosis with a very high degree of accuracy and reliability. Diagnostic correlation performed between the spectra and standard synoptic pathology findings contain detail regarding the pathology (malignant versus benign), vascular invasion by the primary cancer and lymph node involvement of the excised axillary lymph nodes. The classification strategy consisted of three stages: pre-processing of MR magnitude spectra to identify optimal spectral regions, cross-validated Linear Discriminant Analysis, and classification aggregation via Computerised Consensus Diagnosis. Malignant tissue was distinguished from benign lesions with an overall accuracy of 93%.
    Type: Grant
    Filed: February 26, 2008
    Date of Patent: March 26, 2013
    Inventors: Carolyn E. Mountford, Peter Russell, Ian C. P. Smith, Rajmund L. Somorjai
  • Publication number: 20120238862
    Abstract: A system and method identifies different components of the pain experience (nociceptive (tissue damage), neuropathic (nerve damage) and psychological) and their relative contributions by the use of magnetic resonance spectroscopy (MRS) to measure absolute and relative concentrations of metabolites in specific brain regions in the central nervous system or brain. The system and method can be used as a diagnostic tool for the assessment of the relative contribution of different aspects of the pain experience as well as monitoring of response to interventions directed at modifying these components.
    Type: Application
    Filed: March 21, 2012
    Publication date: September 20, 2012
    Inventors: Philip John Siddall, Carolyn E. Mountford, Anne Woodhouse, Peter Stanwell, Rajmund L. Somorjai
  • Patent number: 7676254
    Abstract: A system and method identifies different components of the pain experience (nociceptive (tissue damage), neuropathic (nerve damage) and psychological) and their relative contributions by the use of magnetic resonance spectroscopy (MRS) to measure absolute and relative concentrations of metabolites in specific brain regions in the central nervous system or brain. The system and method can be used as a diagnostic tool for the assessment of the relative contribution of different aspects of the pain experience as well as monitoring of response to interventions directed at modifying these components.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: March 9, 2010
    Assignee: Institute for Magnetic Resonance Research
    Inventors: Philip John Siddall, Carolyn E. Mountford, Anne Woodhouse, Peter Stanwell, Rajmund L. Somorjai
  • Publication number: 20080219932
    Abstract: Robust classification methods analyse magnetic resonance spectroscopy (MRS) data (spectra) of fine needle aspirates taken from breast tumours. The resultant data when compared with the histopathology and clinical criteria provide computerized classification-based diagnosis and prognosis with a very high degree of accuracy and reliability. Diagnostic correlation performed between the spectra and standard synoptic pathology findings contain detail regarding the pathology (malignant versus benign), vascular invasion by the primary cancer and lymph node involvement of the excised axillary lymph nodes. The classification strategy consisted of three stages: pre-processing of MR magnitude spectra to identify optimal spectral regions, cross-validated Linear Discriminant Analysis, and classification aggregation via Computerised Consensus Diagnosis. Malignant tissue was distinguished from benign lesions with an overall accuracy of 93%.
    Type: Application
    Filed: February 26, 2008
    Publication date: September 11, 2008
    Inventors: Carolyn E. Mountford, Peter Russell, Ian C.P. Smith, Rajmund L. Somorjai
  • Patent number: 7335511
    Abstract: Robust classification methods analyze magnetic resonance spectroscopy (MRS) data (spectra) of fine needle aspirates taken from breast tumors. The resultant data when compared with the histopathology and clinical criteria provide computerized classification-based diagnosis and prognosis with a very high degree of accuracy and reliability. Diagnostic correlation performed between the spectra and standard synoptic pathology findings contain detail regarding the pathology (malignant versus benign), vascular invasion by the primary cancer and lymph node involvement of the excised axillary lymph nodes. The classification strategy consisted of three stages: pre-processing of MR magnitude spectra to identify optimal spectral regions, cross-validated Linear Discriminant Analysis, and classification aggregation via Computerised Consensus Diagnosis. Malignant tissue was distinguished from benign lesions with an overall accuracy of 93%.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: February 26, 2008
    Assignees: University of Sydney, National Research Council of Canada
    Inventors: Carolyn E. Mountford, Peter Russell, Ian C. P. Smith, Rajmund L. Somorjai
  • Patent number: 6835572
    Abstract: Robust classification methods analyse magnetic resonance spectroscopy (MRS) data (spectra) of fine needle aspirates taken from breast tumours. The resultant data when compared with the histopathology and clinical criteria provide computerized classification-based diagnosis and prognosis with a very high degree of accuracy and reliability. Diagnostic correlation performed between the spectra and standard synoptic pathology findings contain detail regarding the pathology (malignant versus benign), vascular invasion by the primary cancer and lymph node involvement of the excised axillary lymph nodes. The classification strategy consisted of three stages: pre-processing of MR magnitude spectra to identify optimal spectral regions, cross-validated Linear Discriminant Analysis, and classification aggregation via Computerised Consensus Diagnosis. Malignant tissue was distinguished from benign lesions with an overall accuracy of 93%.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: December 28, 2004
    Assignees: Institute for Magnetic Resonance Research, National Research Council of Canada
    Inventors: Carolyn E. Mountford, Peter Russell, Ian C. P. Smith, Rajmund L. Somorjai
  • Publication number: 20030097059
    Abstract: A statistical classifier identifies microorganisms, such as bacteria and fungi, using magnetic resonance spectroscopy, with multivariate analysis.
    Type: Application
    Filed: February 21, 2002
    Publication date: May 22, 2003
    Inventors: Tania C. Sorrell, Carolyn E. Mountford, Uwe Himmelreich, Roger Bourne, Rajmund L. Somorjai
  • Patent number: 5318031
    Abstract: In a method for determining chemical states of living animal or human tissue using nuclear magnetic resonance with a homogeneous constant magnetic field, the tissue is measured by means of a high-resolution nuclear magnetic resonance measurement and the measured values obtained are then evaluated by comparison with measured values from resonance measurements on comparable tissue to determine whether the chemical state of the tissue corresponds to a chemical normal state or to a deviating abnormal state. In order to enable a determination of chemical intermediate states to be made, it is proposed to compare the measured values obtained with such a series of reference measurements which also contain the detectable characteristic transition states between the chemical normal state and the abnormal end state and that the chemical transition state of the measured tissue sample is determined from the comparison.
    Type: Grant
    Filed: May 19, 1992
    Date of Patent: June 7, 1994
    Assignee: Bruker Analytische Messtechnik GmbH
    Inventors: Carolyn E. Mountford, Peter Russell