Patents by Inventor Carsten Boye Knudsen

Carsten Boye Knudsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GIP-GLP-1 dual agonist compounds and methods
    Patent number: 11008375
    Abstract: The present invention relates to acylated GIP analogues which have dual GIP and GLP-1 activity, and their use in the treatment of metabolic disorders.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: May 18, 2021
    Assignee: Zealand Pharma A/S
    Inventors: Anne Pernille Tofteng Shelton, Pia Nørregaard, Jacob Ulrik Fog, Carsten Boye Knudsen
  • GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS
    Publication number: 20190218270
    Abstract: The present invention relates to acylated GIP analogues which have dual GIP and GLP-1 activity, and their use in the treatment of metabolic disorders.
    Type: Application
    Filed: August 27, 2018
    Publication date: July 18, 2019
    Inventors: Anne Pernille Tofteng SHELTON, Pia NØRREGAARD, Jacob Ulrik FOG, Carsten Boye KNUDSEN
  • GIP-GLP-1 dual agonist compounds and methods
    Patent number: 10093713
    Abstract: The present invention relates to acylated GIP analogs which have dual GIP and GLP-1 activity, and their use in the treatment of metabolic disorders.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: October 9, 2018
    Assignee: Zealand Pharma A/S
    Inventors: Anne Pernille Tofteng Shelton, Pia Nørregaard, Jacob Ulrik Fog, Carsten Boye Knudsen
  • GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS
    Publication number: 20160280754
    Abstract: The present invention relates to acylated GIP analogues which have dual GIP and GLP-1 activity, and their use in the treatment of metabolic disorders.
    Type: Application
    Filed: November 6, 2014
    Publication date: September 29, 2016
    Inventors: Anne Pernille Tofteng SHELTON, Pia NØRREGAARD, Jacob Ulrik FOG, Carsten Boye KNUDSEN
  • TRUNCATED PTH PEPTIDES WITH A CYCLIC CONFORMATION
    Publication number: 20100048462
    Abstract: The present invention provides PTH peptides which are cyclised substitution analogues of the truncated PTH fragment PTH (1-17) and which preferably retain the desired or similar biological activity of human PTH (1-34).
    Type: Application
    Filed: December 6, 2007
    Publication date: February 25, 2010
    Applicant: Zealand Pharma A/S
    Inventors: Trine Skovlund Ryge, Martin Stahlhut, Carsten Boye Knudsen, Bjarne Due Larsen
  • STABILIZED EXENDIN-4 COMPOUNDS
    Publication number: 20090208565
    Abstract: The present invention discloses compositions comprising a stabilized Exendin-4 (1-39) and related compounds. The invention describes stabilized Exendin-4 agonists that include at least one modified amino acid residue particularly at positions Gln13, Met14, Trp25, or Asn28 of the Exendin-4 (1-39) molecule. Disclosed are preferred modifications of deaminated, hydrolyzed, oxidized, or isomerized reaction products of the specified amino acid residues corresponding to the same positions in the Exendin-4 (1-39) molecule. The invention also relates to methods of making and using the stabilized Exendin compounds, such as for the treatment of diabetes.
    Type: Application
    Filed: May 4, 2009
    Publication date: August 20, 2009
    Applicant: Zealand Pharma A/S
    Inventors: Kirsten Ebbehoj, Trine Jepsen, Carsten Boye Knudsen, Bjarne Due Larsen, David Knott
  • Stabilized Exendin-4 compounds
    Patent number: 7544657
    Abstract: The present invention disclosed compositions comprising a stabilized Exendin-4 (1-39) and related compounds. The invention describes stabilized Exendin-4 agonists that include at least one modified amino acid residue particularly at positions Gln 13, Met14, Trp25, or Asn28 of the Exendin-4 (1-39) molecule. Disclosed are preferred modifications of deaminated, hydrolyzed, oxidized, or isomerized reaction products of the specified amino acid residues corresponding to the same positions in the Exendin-4 molecule. The invention also relates to methods of making and using the stabilized Exendin compounds, such as for the treatment of diabetes.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: June 9, 2009
    Assignee: Zealand Pharma A/S
    Inventors: Kirsten Ebbehøj, Trine Jepsen, Carsten Boye Knudsen, Bjarne Due Larsen, David Knott
  • Nociceptin Analogues and Uses Thereof
    Publication number: 20080287478
    Abstract: The present invention relates to nociceptin analogues and uses thereof to modulate biological functions. In one aspect, the invention provides modified triazo-spiro compounds that include at least one specialized chemical group that is bound to the compounds. The invention has a wide range of applications including providing a new class of therapeutically useful aquatics.
    Type: Application
    Filed: May 21, 2004
    Publication date: November 20, 2008
    Inventors: Lars Bo Laurenborg Hansen, Bjarne Due Larsen, Christian Thorkildsen, Carsten Boye Knudsen