Abstract: Methods and systems are provided for coatings of a portion of an engine block shaping a combustion chamber. In one example, the engine block includes a first coating with a thermal conductivity higher than a conductivity of the engine block arranged in an upper region of the combustion chamber and a second coating with a thermal conductivity lower than the conductivity of the engine block arranged in a lower region of the combustion chamber, and where the second coating touches the first coating.

Abstract: The invention provides a liquid aqueous pharmaceutical formulation comprising a human anti-TNFa antibody, or antigen-binding portion thereof, which reduces pain associated with injection in a subject by at least about 50% when compared to injecting an otherwise identical formulation comprising at least one salt and/or at least one buffer. The invention also provides a liquid aqueous pharmaceutical formulation comprising a human anti-TNFa antibody, or antigen-binding portion thereof, having increased bioavailability upon subcutaneous administration into a subject. The formulation may comprise a therapeutic protein, such as a human anti-TNF-alpha antibody, or an antigen-binding portion thereof, or a biosimilar thereof.

Abstract: The internal combustion engine is provided which may include a cylinder head, a turbine, and a turbine housing. The turbine housing may include an exhaust gas passage, at least one coolant fluid passage, and a wall between the passages. The wall may have a first area (Aexhaust) disposed to absorb heat from an exhaust flow passing through the exhaust gas passage, and a second area (Acoolant) disposed to transfer heat from the wall to be absorbed by a coolant fluid flow passing through the at least one coolant fluid passage, wherein the following applies: Acoolant/Aexhaust?1.2.

Abstract: Methods and systems are provided for a ventilation arrangement. In one example, a system may include a compact ventilation arrangement arranged within a space between an intake manifold and a cylinder head. A pump of the ventilation arrangement arrange adjacent the cylinder head.

Abstract: There is provided an arrangement of an internal combustion engine with a sequentially parallel twin turbocharger, in which at least one turbocharger has an electrical energy converter which can be used optionally as a motor for driving a compressor in the lower rotational speed range of the internal combustion engine or as a generator for charging a connected battery.

Abstract: Methods and systems are provided for a turbocharger. In one example, the turbocharger may include one or more cooling devices for cooling a compressor. The cooling devices may include a ventilation system arranged in a compressor impeller and shaft, the ventilation system configured to allow ambient air to flow into the shaft without being compressed.

Abstract: A method for operating a boosted internal combustion engine is provided. The engine includes a first cylinder in a first cylinder group and a second cylinder in a second cylinder group, each of the first and second cylinders having two activatable outlet openings adjoined by an exhaust line, one of the outlet openings of each of the first and second cylinders coupled to a first turbocharger including a first turbine and one of the outlet openings of each of the cylinders coupled to a second turbocharger including a second turbine, the method comprising: if engine load is less than a threshold load value implementing a first operating mode that includes deactivating the second cylinder, deactivating one of the activatable outlet openings in the first cylinder, and activating one of the activatable outlet opening in the first cylinder.

Abstract: A method for operating an internal combustion engine is provided. The method includes during a first operating condition, operating two primary cylinders and two secondary cylinders to perform combustion, the two primary and secondary cylinders arranged in an inline configuration, the two primary cylinder adjacent to one another, the two secondary cylinders adjacent to one another, and the secondary cylinders positioned 175°-185° out of phase relative to the two primary cylinders and during a second operating condition, selectively deactivating the two secondary cylinders to perform combustion in only the two primary cylinders.

Abstract: An internal combustion engine has a cylinder head with at least one cylinder and a cooled turbine. Each cylinder has at least one outlet opening adjoined by an exhaust line for discharging exhaust gases from the cylinder. The exhaust line issues into an inlet region transitioning into an exhaust gas-conducting flow duct of the turbine. The turbine has at least one rotor mounted on a rotatable shaft in a turbine housing. The turbine has at least one coolant duct which is integrated in the housing and which is delimited and formed by at least one wall of the housing to form a cooling arrangement. The at least one wall of the turbine housing that delimits the at least one coolant duct is provided, at least in regions, with a thermal insulation.

Abstract: A method of producing an enamel coating for a cylinder bore in a cylinder block of an internal combustion engine is provided. The method also provides for coating a cast iron gray cylinder block with an enamel coating.

Abstract: The internal combustion engine is provided which may include a cylinder head, a turbine, and a turbine housing. The turbine housing may include an exhaust gas passage, at least one coolant fluid passage, and a wall between the passages. The wall may have a first area (Aexhaust) disposed to absorb heat from an exhaust flow passing through the exhaust gas passage, and a second area (Acoolant) disposed to transfer heat from the wall to be absorbed by a coolant fluid flow passing through the at least one coolant fluid passage, wherein the following applies: Acoolant/Aexhaust?1.2.

Abstract: The application describes a system for an engine comprising a direct injection nozzle for injecting gaseous fuel into a cylinder of an engine in a second operating mode; an intake injection nozzle for injecting liquid fuel into an intake port of the engine in a first operating mode; and a valve gear suitable to adjust timing of opening and closing of an inlet valve. Preferential injection of a gaseous fuel such as compressed natural gas directly into the cylinder increases efficiency and allows for reduced heat exposure to the lesser used liquid gas injectors mounted in the intake port, reducing coking of these injectors.

Abstract: A method for partial cylinder cutoff is provided. The method comprises operating a multi-cylinder internal combustion engine with applied ignition, in which an odd number n of cylinders is arranged in line, and during partial-load operation when engine load is below threshold, enabling a partial cutoff of the cylinders, the partial cutoff comprising operating each cylinder only intermittently such that each cylinder is fired and cut off in turn at an interval of (2*720° CA)/n.

Abstract: To illuminate a structure 5 with informational content on components 3, 20 of a filling opening in a laundry appliance, particularly a washing machine or a washer/dryer, components 3, 20, which are made of a transparent or translucent material, have a pot-shaped laundry deflector 20 and a window cover 3 lying at least approximately flush with the front face 1 of the laundry appliance. Components 3, 20 bear lettering 4, 16 and/or a symbol to be illuminated. Light-emitting elements 6, 17 are arranged opposite lateral edge faces 10, 15 of at least one of the components 3, 20, the light beams 9, 19 emitted by said elements being directed onto the edge faces 10, 15. The lettering 4, 16 or the symbol consists of a three-dimensional structure 5 in the material with an at least microscopically small extension into the material.

Abstract: An engine method, comprising turning off a second cylinder group in response to engine load falling below a first threshold, the second cylinder group including a first outer most cylinder and its immediately adjacent cylinder and turning on the second cylinder group in response to engine load raising above a second threshold and operating a first cylinder group constantly throughout engine operation; the first cylinder group including a second outer most cylinder and its immediately adjacent cylinder. By this method, engine efficiency may increase during partial load operating conditions from low engine loads.

Abstract: There is provided an arrangement of an internal combustion engine with a sequentially parallel twin turbocharger, in which at least one turbocharger has an electrical energy converter which can be used optionally as a motor for driving a compressor in the lower rotational speed range of the internal combustion engine or as a generator for charging a connected battery.

Abstract: An aircraft including a device for influencing the directional stability of the aircraft is provided. The device includes a control-input device; a flight control device; a sensor device for acquiring the rotation rates, including the yaw rates, of the aircraft; and at least one actuator, which is coupled with ailerons, spoilers, an elevator and a rudder. The flight control device includes a control function generating adjusting commands for the actuators for controlling the aircraft according to control commands. The aircraft includes two tail-mounted flaps, each including an actuator connected with the flight control device, situated symmetrically to each other and on opposite sides of the fuselage, and movable between retracted and extended positions. The control function is designed such that the adjusting commands that are generated on the basis of the control commands depending on the acquired rotation rates include adjusting commands to the actuators of the tail-mounted flaps.

Abstract: The invention provides a liquid aqueous pharmaceutical formulation comprising a human anti-TNFa antibody, or antigen-binding portion thereof, which reduces pain associated with injection in a subject by at least about 50% when compared to injecting an otherwise identical formulation comprising at least one salt and/or at least one buffer. The invention also provides a liquid aqueous pharmaceutical formulation comprising a human anti-TNFa antibody, or antigen-binding portion thereof, having increased bioavailability upon subcutaneous administration into a subject. The formulation may comprise a therapeutic protein, such as a human anti-TNF-alpha antibody, or an antigen-binding portion thereof, or a biosimilar thereof.