Patents by Inventor Carter Van Waes

Carter Van Waes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MICRORNAS AND METHODS OF THEIR USE
    Publication number: 20230295631
    Abstract: Disclosed herein are methods of treating a tumor in a subject, including administering to the subject one or more miRNA nucleic acids or variants (such as mimics or mimetics) thereof with altered expression in the tumor. Also disclosed herein are compositions including one or more miRNA nucleic acids. In some examples, the miRNA nucleic acids are modified miRNAs, for example, and miRNA nucleic acid including one or more modified nucleotides and/or a 5?-end and/or 3?-end modification. In particular examples, the modified miRNA nucleic acid is an miR-30a nucleic acid. Further disclosed herein are methods of diagnosing a subject as having a tumor with altered expression of one or more miRNA nucleic acids. In some embodiments, the methods include detecting expression of one or more miRNAs in a sample from the subject and comparing the expression in the sample from the subject to a control.
    Type: Application
    Filed: April 14, 2023
    Publication date: September 21, 2023
    Applicants: The United States of America, as represented by the Secretary, Dept. of Health and Human Services, miRecule, Inc.
    Inventors: Anthony D. Saleh, Carter Van Waes, Zhong Chen, Hui Cheng
  • MicroRNAs and methods of their use
    Patent number: 11655469
    Abstract: Disclosed herein are methods of treating a tumor in a subject, including administering to the subject one or more miRNA nucleic acids or variants (such as mimics or mimetics) thereof with altered expression in the tumor. Also disclosed herein are compositions including one or more miRNA nucleic acids. In some examples, the miRNA nucleic acids are modified miRNAs, for example, and miRNA nucleic acid including one or more modified nucleotides and/or a 5?-end and/or 3?-end modification. In particular examples, the modified miRNA nucleic acid is an miR-30a nucleic acid. Further disclosed herein are methods of diagnosing a subject as having a tumor with altered expression of one or more miRNA nucleic acids. In some embodiments, the methods include detecting expression of one or more miRNAs in a sample from the subject and comparing the expression in the sample from the subject to a control.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: May 23, 2023
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, miRenlo, Inc.
    Inventors: Anthony D. Saleh, Carter Van Waes, Zhong Chen, Hui Cheng
  • MICRORNAS AND METHODS OF THEIR USE
    Publication number: 20190284554
    Abstract: Disclosed herein are methods of treating a tumor in a subject, including administering to the subject one or more miRNA nucleic acids or variants (such as mimics or mimetics) thereof with altered expression in the tumor. Also disclosed herein are compositions including one or more miRNA nucleic acids. In some examples, the miRNA nucleic acids are modified miRNAs, for example, and miRNA nucleic acid including one or more modified nucleotides and/or a 5?-end and/or 3?-end modification. In particular examples, the modified miRNA nucleic acid is an miR-30a nucleic acid. Further disclosed herein are methods of diagnosing a subject as having a tumor with altered expression of one or more miRNA nucleic acids. In some embodiments, the methods include detecting expression of one or more miRNAs in a sample from the subject and comparing the expression in the sample from the subject to a control.
    Type: Application
    Filed: March 7, 2017
    Publication date: September 19, 2019
    Applicants: The United States of America, as represented by the Secretary, Dept. of Health and Human Services, miRecule, Inc.
    Inventors: Anthony D. Saleh, Carter Van Waes, Zhong Chen, Hui Cheng