Patents by Inventor Casandra L. Hoffman

Casandra L. Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for inhibiting formation of and/or disrupting bacterial biofilms and methods of use therefor
    Patent number: 11207378
    Abstract: Provided are compositions that include an effective amount of a peptide or polypeptide derived from a Bordetella ACT AC domain, optionally wherein the peptide or polypeptide is 80-100% identical to an amino acid sequence as set forth in SEQ ID NOs: 1-5 and 44-53. Also provided are methods of using the same for preventing and/or treating a diseases, disorders, and conditions associated with the presence and/or development of biofilm; and for reducing the incidence of nosocomial infections; for inhibiting biofilm development and/or for reducing or eliminating biofilm present on medical, dental, and industrial surfaces.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: December 28, 2021
    Assignee: University of Virginia Patent Foundation
    Inventors: Erik L. Hewlett, Casandra L. Hoffman
  • COMPOSITIONS FOR INHIBITING FORMATION OF AND/OR DISRUPTING BACTERIAL BIOFILMS AND METHODS OF USE THEREFOR
    Publication number: 20190111106
    Abstract: Provided are compositions that include an effective amount of a peptide or polypeptide derived from a Bordetella ACT AC domain, optionally wherein the peptide or polypeptide is 80-100% identical to an amino acid sequence as set forth in SEQ ID NOs: 1-5 and 44-53. Also provided are methods of using the same for preventing and/or treating a diseases, disorders, and conditions associated with the presence and/or development of biofilm; and for reducing the incidence of nosocomial infections; for inhibiting biofilm development and/or for reducing or eliminating biofilm present on medical, dental, and industrial surfaces.
    Type: Application
    Filed: April 4, 2017
    Publication date: April 18, 2019
    Inventors: Erik L. Hewlett, Casandra L. Hoffman, Ph.D.