Patents by Inventor Casey C. Case

Casey C. Case has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATMENT OF RETINAL DEGENERATION
    Publication number: 20160271181
    Abstract: Disclosed herein axe methods and compositions for treating retinal degeneration, such as occurs in retinitis pigmentosa and age-related macular degeneration, using descendents of marrow adherent stem cells that have been engineered to express an exogenous Notch intracellular domain.
    Type: Application
    Filed: March 21, 2016
    Publication date: September 22, 2016
    Applicant: SanBio, Inc.
    Inventors: Casey C. CASE, Toru KAWANISHI, Noriyuki KUNO
  • METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND VASCULOGENESIS
    Publication number: 20160263159
    Abstract: Disclosed herein are methods and compositions for stimulating angiogenesis, using cells descended from marrow adherent stromal cells that have been transfected with sequences encoding a Notch intracellular domain. Applications of these methods and compositions include treatment of ischemic disorders such as stroke.
    Type: Application
    Filed: March 7, 2016
    Publication date: September 15, 2016
    Applicant: SanBio, Inc.
    Inventors: Monique DAO, Ciara TATE, Casey C. CASE
  • Methods and compositions for treatment of retinal degeneration
    Patent number: 9326999
    Abstract: Disclosed herein are methods and compositions for treating retinal degeneration, such as occurs in retinitis pigmentosa and age-related macular degeneration, using descendents of marrow adherent stem cells that have been engineered to express an exogenous Notch intracellular domain.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: May 3, 2016
    Assignee: SanBio, Inc.
    Inventors: Casey C. Case, Toru Kawanishi, Noriyuki Kuno
  • METHODS AND COMPOSITIONS FOR TREATMENT OF TRAUMATIC BRAIN INJURY AND FOR MODULATION OF MIGRATION OF NEUROGENIC CELLS
    Publication number: 20150197741
    Abstract: Disclosed herein are methods for the treatment of traumatic brain injury by transplantation of cells descended from marrow adherent stem cells that express an exogenous Notch intracellular domain. The transplanted cells form a pathway along which endogenous neurogenic cells proliferate and migrate from the subventricular zone to the site of injury.
    Type: Application
    Filed: September 18, 2014
    Publication date: July 16, 2015
    Inventors: Cesar V. Borlongan, Casey C. Case
  • REGULATION OF ENDOGENOUS GENE EXPRESSION IN CELLS USING ZINC FINGER PROTEINS
    Publication number: 20140325691
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: June 5, 2014
    Publication date: October 30, 2014
    Applicant: Sangamo BioSciences, Inc.
    Inventors: George Norbert Cox III, Casey C. Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • METHODS AND COMPOSITIONS FOR MODULATING PERIPHERAL IMMUNE FUNCTION
    Publication number: 20140286918
    Abstract: Disclosed herein are cell preparations useful for modulating various peripheral immune functions, methods for making said cell preparations, and methods for their use.
    Type: Application
    Filed: June 6, 2014
    Publication date: September 25, 2014
    Inventors: Mo Dao, Casey C. Case
  • METHODS AND COMPOSITIONS FOR TREATMENT OF RETINAL DEGENERATION
    Publication number: 20140219976
    Abstract: Disclosed herein are methods and compositions for treating glaucoma, using descendents of marrow adherent stem cells that have been engineered to express an exogenous Notch intracellular domain.
    Type: Application
    Filed: April 3, 2014
    Publication date: August 7, 2014
    Inventors: Casey C. Case, Toru Kawanishi, Noriyuki Kuno, Ernest Yankee
  • Methods and compositions for modulating peripheral immune function
    Patent number: 8785190
    Abstract: Disclosed herein are cell preparations useful for modulating various peripheral immune functions, methods for making said cell preparations, and methods for their use.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: July 22, 2014
    Assignee: SanBio, Inc.
    Inventors: Mo Dao, Casey C. Case
  • METHODS AND COMPOSITIONS FOR TREATMENT OF RETINAL DEGENERATION
    Publication number: 20140099291
    Abstract: Disclosed herein are methods and compositions for treating retinal degeneration, such as occurs in retinitis pigmentosa and age-related macular degeneration, using descendents of marrow adherent stem cells that have been engineered to express an exogenous Notch intracellular domain.
    Type: Application
    Filed: March 13, 2013
    Publication date: April 10, 2014
    Applicant: SANBIO, INC.
    Inventors: Casey C. Case, Toru Kawanishi, Noriyuki Kuno
  • NEUROGENIC AND GLIOGENIC FACTORS AND ASSAYS THEREFOR
    Publication number: 20130210000
    Abstract: Disclosed herein are quantitative assays for measuring the potential of a substance, or a source of a substance, to promote neurogenesis and gliogenesis. Substances that promote neurogenesis and gliogenesis are also disclosed.
    Type: Application
    Filed: August 20, 2012
    Publication date: August 15, 2013
    Inventors: Irina Aizman, Casey C. Case
  • METHODS AND COMPOSITIONS FOR MODULATING PERIPHERAL IMMUNE FUNCTION
    Publication number: 20130095084
    Abstract: Disclosed herein are cell preparations useful for modulating various peripheral immune functions, methods for making said cell preparations, and methods for their use.
    Type: Application
    Filed: April 6, 2012
    Publication date: April 18, 2013
    Inventors: Mo Dao, Casey C. Case
  • Randomized libraries of zinc finger proteins
    Patent number: 7943553
    Abstract: The present invention relates to methods of using libraries of randomized zinc finger proteins to identify genes associated with selected phenotypes.
    Type: Grant
    Filed: July 12, 2006
    Date of Patent: May 17, 2011
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Casey C. Case, Edward J. Rebar, Andrew Jamieson
  • Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
    Patent number: 7788044
    Abstract: The invention provides criteria and methods for selecting optimum subsequence(s) from a target gene for targeting by a zinc finger protein. Some of the methods of target site selection seek to identify one or more target segments having a DNA motif containing one or more so-called D-able subsites having the sequence 5?NNGK3?. Other methods of the invention are directed to selection of target segments within target genes using a correspondence regime between different triplets of three bases and the three possible positions of a triplet within a nine-base site. In another aspect, the invention provides methods of designing zinc finger proteins that bind to a preselected target site. These methods can be used following the preselection of target sites according to the procedures and criteria described above. The methods of design use a database containing information about previously characterized zinc finger proteins.
    Type: Grant
    Filed: February 12, 2007
    Date of Patent: August 31, 2010
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Stephen P. Eisenberg, Casey C. Case, George N. Cox, III, Andrew Jamieson, Edward J. Rebar
  • Randomized libraries of zinc finger proteins
    Patent number: 7491531
    Abstract: The present invention relates to methods of using libraries of randomized zinc finger proteins to identify genes associated with selected phenotypes.
    Type: Grant
    Filed: January 6, 2003
    Date of Patent: February 17, 2009
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Casey C. Case, Edward J. Rebar, Andrew Jamieson
  • Functional genomics using zinc finger proteins
    Patent number: 7235354
    Abstract: The present invention provides methods of regulating gene expression using recombinant zinc finger proteins, for functional genomics and target validation applications.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: June 26, 2007
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Casey C. Case, Lei Zhang, Fyodor Urnov
  • Modulation of endogenous gene expression in cells
    Patent number: 7220719
    Abstract: Disclosed herein are methods and compositions for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: May 22, 2007
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Casey C. Case, Elizabeth Wolffe, legal representative, Fyodor Urnov, Albert Lai, Andrew Snowden, Siyuan Tan, Philip Gregory, Alan Wolffe, deceased
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Patent number: 7013219
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using engineered zinc finger proteins.
    Type: Grant
    Filed: September 16, 2002
    Date of Patent: March 14, 2006
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Casey C. Case, George N. Cox, III, Stephen P. Eisenberg, Qiang Liu, Edward J. Rebar
  • Modulation of endogenous gene expression in cells
    Patent number: 6933113
    Abstract: Disclosed herein are methods and compositions for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: August 23, 2005
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Casey C. Case, Elizabeth Wolffe, Fyodor Urnov, Albert Lai, Andrew Snowden, Siyuan Tan, Philip Gregory, Alan Wolffe
  • Modulation of endogenous gene expression in cells
    Publication number: 20040204345
    Abstract: Disclosed herein are methods and compositions for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: May 13, 2004
    Publication date: October 14, 2004
    Applicant: Sangamo Biosciences, Inc.
    Inventors: Casey C. Case, Alan Wolffe, Elizabeth J. Wolffe, Fyodor Urnov, Albert Lai, Andrew Snowden, Siyuan Tan, Philip Gregory
  • Functional genomics using zinc finger proteins
    Publication number: 20040203064
    Abstract: The present invention provides methods of regulating gene expression using recombinant zinc finger proteins, for functional genomics and target validation applications.
    Type: Application
    Filed: May 12, 2004
    Publication date: October 14, 2004
    Applicant: Sangamo Biosciences, Inc.
    Inventors: Casey C. Case, Lei Zhang, Fyodor Urnov