Patents by Inventor Casey Keith Jager

Casey Keith Jager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MANUFACTURING A BIFUNCTIONAL COMPOUND, ULTRAPURE FORMS OF THE BIFUNCTIONAL COMPOUND, AND DOSAGE FORMS COMPRISING THE SAME
    Publication number: 20230012321
    Abstract: The present disclosure relates to ultra-pure forms, polymorphs, amorphous forms, and formulations of N-[(1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl]-6-[4-({4-[2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]piperazin-1-yl}methyl)piperidin-1-yl]pyridazine-3-carboxamide, referred to herein as Compound A: The present disclosure also relates methods of manufacturing and purifying the same, as well as intermediates useful in the synthesis of Compound A. The ultra-pure forms, polymorphs, amorphous forms, and formulations of Compound A can be used as therapeutic agents for the treatment of various diseases and conditions such as cancer.
    Type: Application
    Filed: May 6, 2021
    Publication date: January 12, 2023
    Applicant: Arvinas Operations, Inc.
    Inventors: Laura E.N. ALLAN, Chungpin Herman CHEN, Hanqing DONG, Robert J. DUGUID, John A. GROSSO, Royal J. HASKELL, III, Casey Keith JAGER, Venkata A. KATTUBOINA, Aditya Mohan KAUSHAL, Samuel Elliott KENNEDY, Rhys LLOYD, Miranda Annell NEESER, Yuping QIU, Hayley REECE, Maxwell Marco REEVE, Joseph P. REO, Jerod ROBERTSON, Mohammad Mehdi ZAHEDI
  • Formulations of 4-Methyl-5-(Pyrazin-2-yl)-3H-1,2-Dithiole-3-Thione, Taste-Modified Formulations, and Methods of Making and Using Same
    Publication number: 20220296589
    Abstract: This disclosure provides, among other things, compositions comprising quantities of oltipraz crystals, as well as method of making such compositions, and method of treating patients using such compositions. Taste-modified compositions also are provided.
    Type: Application
    Filed: October 25, 2021
    Publication date: September 22, 2022
    Inventors: Anthony Chris GARLAND, Barbara-Jean Anne BORMANN-KENNEDY, Bomi FRAMROZE, Bret BERNER, Michael Edward GRASS, Casey Keith JAGER, Corey Jay BLOOM, Mark Joseph KASTANTIN, Romain BACHELARD
  • Formulations of 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione, and methods of making and using same
    Patent number: 11426403
    Abstract: This disclosure provides, among other things, compositions comprising quantities of oltipraz crystals, as well as method of making such compositions, and method of treating patients using such compositions.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: August 30, 2022
    Assignee: ST IP Holding AG
    Inventors: Anthony Chris Garland, Barbara-Jean Anne Bormann-Kennedy, Bomi Framroze, Bret Berner, Michael Edward Grass, Casey Keith Jager, Jay Corey Bloom, Mark Joseph Kastantin
  • Formulations of 4-methyl-5-(pyrazin-2-yl)-3H-l,2-dithiole-3-thione, taste-modified formulations, and methods of making and using same
    Patent number: 11185544
    Abstract: This disclosure provides, among other things, compositions comprising quantities of oltipraz crystals, as well as method of making such compositions, and method of treating patients using such compositions. Taste-modified compositions also are provided.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: November 30, 2021
    Assignee: ST IP Holding AG
    Inventors: Anthony Chris Garland, Barbara-Jean Anne Bormann-Kennedy, Bomi Framroze, Bret Berner, Michael Edward Grass, Casey Keith Jager, Corey Jay Bloom, Mark Joseph Kastantin, Romain Bachelard
  • Formulations of 4-Methyl-5-(Pyrazin-2-yl)-3H-1,2-Dithiole-3-Thione, and Methods of Making and Using Same
    Publication number: 20190209556
    Abstract: This disclosure provides, among other things, compositions comprising quantities of oltipraz crystals, as well as method of making such compositions, and method of treating patients using such compositions.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 11, 2019
    Inventors: Anthony Chris Garland, Barbara-Jean Anne Bormann-Kennedy, Bomi Framroze, Bret Berner, Michael Edward Grass, Casey Keith Jager, Jay Corey Bloom, Mark Joseph Kastantin
  • Formulations of 4-Methyl-5-(Pyrazin-2-yl)-3H-1,2-Dithiole-3-Thione, Taste-Modified Formulations, and Methods of Making and Using Same
    Publication number: 20190209557
    Abstract: This disclosure provides, among other things, compositions comprising quantities of oltipraz crystals, as well as method of making such compositions, and method of treating patients using such compositions. Taste-modified compositions also are provided.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 11, 2019
    Inventors: Anthony Chris Garland, Barbara-Jean Anne Bormann-Kennedy, Bomi Framroze, Bret Berner, Michael Edward Grass, Casey Keith Jager, Jay Corey Bloom, Mark Joseph Kastantin, Romain Bachelard