Patents by Inventor Catherine A. Bothof
Catherine A. Bothof has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150166703Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.Type: ApplicationFiled: January 20, 2015Publication date: June 18, 2015Inventors: Jerald K. Rasmussen, Catherine A. Bothof, Kannan Seshadri, Erin A. Satterwhite, Robert T. Fitzsimons, JR., James L. Hembre, Mahfuza B. Ali
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Patent number: 9056316Abstract: Semi-interpenetrating polymeric networks are described. More specifically, the semi-interpenetrating polymeric networks include at least two polymers that are closely associated. The first polymer is an ionic polymer that is not crosslinked. The second polymer is a cross-linked polymer that can be either another ionic polymer or a non-ionic polymer. Methods of making the semi-interpenetrating polymeric networks, articles containing the semi-interpenetrating polymeric networks, and methods of using the semi-interpenetrating polymeric networks are also described. The semi-interpenetrating polymeric networks can function as ion exchange resins.Type: GrantFiled: June 17, 2011Date of Patent: June 16, 2015Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: Del R. Lawson, James I. Hembre, Jerald K. Rasmussen, Catherine A. Bothof, Kannan Seshadri, Robert T. Fitzsimons, Jr., Andrew W. Rabins, Taib K. Ansera
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Publication number: 20150136698Abstract: Guanidinyl ligand-functionalized polymers, methods of making the same, and substrates bearing a grafted coating of the ligand-functional polymers are described. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, endotoxins and proteins, at pH's near or below the pI's of the biomaterials.Type: ApplicationFiled: May 23, 2013Publication date: May 21, 2015Inventors: Catherine A. Bothof, George W. Griesgraber, James I. Hembre, Jerald K. Rasmussen
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Patent number: 9018267Abstract: Articles that contain a solid support with a grafted chain extending from the solid support, methods of making these articles, and various uses of the articles are described. More specifically, the grafted chain has a functional group that can react with or interact with target compound. Alternatively, the functional group on the grafted chain can react with a modifying agent to provide another group that can react with or interact with the target compound. The grafted chains are attached to the solid support through a ring-opened azlactone group. The articles can be used to purify the target compound or to separate the target compound from other molecules in a sample.Type: GrantFiled: April 16, 2014Date of Patent: April 28, 2015Assignee: 3M Innovative Properties CompanyInventors: Simon K. Shannon, Catherine A. Bothof, Babu N. Gaddam, Jerald K. Rasmussen, Richard B. Ross
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Patent number: 8945896Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.Type: GrantFiled: January 23, 2013Date of Patent: February 3, 2015Assignee: 3M Innovative Properties CompanyInventors: Jerald K. Rasmussen, Catherine A. Bothof, Kannan Seshadri, Erin A. Satterwhite, Robert T. Fitzsimons, Jr., James L. Hembre, Mahfuza B. Ali
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Publication number: 20140364519Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.Type: ApplicationFiled: August 25, 2014Publication date: December 11, 2014Inventors: Catherine A. Bothof, Yi He, Jerald K. Rasmussen, Kannan Seshadri, Clinton P. Waller, JR., Douglas E. Weiss
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Patent number: 8846203Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.Type: GrantFiled: November 27, 2013Date of Patent: September 30, 2014Assignee: 3M Innovative Properties CompanyInventors: Catherine A. Bothof, Yi He, Jerald K. Rasmussen, Kannan Seshadri, Clinton P. Waller, Jr., Douglas E. Weiss
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Publication number: 20140228457Abstract: Articles that contain a solid support with a grafted chain extending from the solid support, methods of making these articles, and various uses of the articles are described. More specifically, the grafted chain has a functional group that can react with or interact with target compound. Alternatively, the functional group on the grafted chain can react with a modifying agent to provide another group that can react with or interact with the target compound. The grafted chains are attached to the solid support through a ring-opened azlactone group. The articles can be used to purify the target compound or to separate the target compound from other molecules in a sample.Type: ApplicationFiled: April 16, 2014Publication date: August 14, 2014Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Simon K. Shannon, Catherine A. Bothof, Babu N. Gaddam, Jerald K. Rasmussen, Richard B. Ross
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Patent number: 8735455Abstract: Articles that contain a solid support with a grafted chain extending from the solid support, methods of making these articles, and various uses of the articles are described. More specifically, the grafted chain has a functional group that can react with or interact with target compound. Alternatively, the functional group on the grafted chain can react with a modifying agent to provide another group that can react with or interact with the target compound. The grafted chains are attached to the solid support through a ring-opened azlactone group. The articles can be used to purify the target compound or to separate the target compound from other molecules in a sample.Type: GrantFiled: October 21, 2013Date of Patent: May 27, 2014Assignee: 3M Innovative Properties CompanyInventors: Simon K. Shannon, Catherine A. Bothof, Babu N. Gaddam, Jerald K. Rasmussen, Richard B. Ross
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Publication number: 20140087445Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.Type: ApplicationFiled: November 27, 2013Publication date: March 27, 2014Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Catherine A. Bothof, Yi He, Jerald K. Rasmussen, Kannan Seshadri, Clinton P. Waller, JR., Douglas E. Weiss
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Patent number: 8652582Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.Type: GrantFiled: May 26, 2009Date of Patent: February 18, 2014Assignee: 3M Innovative Properties CompanyInventors: Catherine A. Bothof, Yi He, Jerald K. Rasmussen, Kannan Seshadri, Clinton P. Waller, Jr., Douglas E. Weiss
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Publication number: 20140046029Abstract: Articles that contain a solid support with a grafted chain extending from the solid support, methods of making these articles, and various uses of the articles are described. More specifically, the grafted chain has a functional group that can react with or interact with target compound. Alternatively, the functional group on the grafted chain can react with a modifying agent to provide another group that can react with or interact with the target compound. The grafted chains are attached to the solid support through a ring-opened azlactone group. The articles can be used to purify the target compound or to separate the target compound from other molecules in a sample.Type: ApplicationFiled: October 21, 2013Publication date: February 13, 2014Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Simon K. Shannon, Catherine A. Bothof, Babu N. Gaddam, Jerald K. Rasmussen, Richard B. Ross
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Patent number: 8592493Abstract: Articles that contain a solid support with a grafted chain extending from the solid support, methods of making these articles, and various uses of the articles are described. More specifically, the grafted chain has a functional group that can react with or interact with target compound. Alternatively, the functional group on the grafted chain can react with a modifying agent to provide another group that can react with or interact with the target compound. The grafted chains are attached to the solid support through a ring-opened azlactone group. The articles can be used to purify the target compound or to separate the target compound from other molecules in a sample.Type: GrantFiled: May 11, 2009Date of Patent: November 26, 2013Assignee: 3M Innovative Properties CompanyInventors: Simon K. Shannon, Catherine A. Bothof, Babu N. Gaddam, Jerald K. Rasmussen, Richard B. Ross
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Patent number: 8459470Abstract: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising cationic aminoalkyl(meth)acryloyl monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as oligonucleotides or monoclonal antibodies (MAb), from a fluid mixture.Type: GrantFiled: December 7, 2012Date of Patent: June 11, 2013Assignee: 3M Innovative Properties CompanyInventors: Douglas E. Weiss, Clinton P. Waller, Jr., Michael R. Berrigan, Andrew W. Rabins, Jeffrey A. Lucas, Kannan Seshadri, Catherine A. Bothof
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Patent number: 8435776Abstract: A method of separating a target biological species from a fluid is disclosed comprising contacting the fluid with a ligand-functionalized polymer comprising: a water soluble or water dispersible aminopolymer functionalized with guanidinyl groups; whereby a complex comprising the functionalized substrate and the target biological species is formed.Type: GrantFiled: February 14, 2011Date of Patent: May 7, 2013Assignee: 3M Innovative Properties CompanyInventors: Jerald K. Rasmussen, Kannan Seshadri, Robert T. Fitzsimons, Jr., James I. Hembre, Catherine A. Bothof, Erin A. Satterwhite, George W. Griesgraber, Yi He, Louis C. Haddad
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Publication number: 20130090397Abstract: Semi-interpenetrating polymeric networks are described. More specifically, the semi-interpenetrating polymeric networks include at least two polymers that are closely associated. The first polymer is an ionic polymer that is not crosslinked. The second polymer is a cross-linked polymer that can be either another ionic polymer or a non-ionic polymer. Methods of making the semi-interpenetrating polymeric networks, articles containing the semi-interpenetrating polymeric networks, and methods of using the semi-interpenetrating polymeric networks are also described. The semi-interpenetrating polymeric networks can function as ion exchange resins.Type: ApplicationFiled: June 17, 2011Publication date: April 11, 2013Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Del R. Lawson, James I. Hembre, Jerald K. Rasmussen, Catherine A. Bothof, Kannan Seshadri, Robert T. Fitzsimons, JR., Andrew W. Rabins, Taib K. Ansera
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Patent number: 8377672Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.Type: GrantFiled: January 7, 2011Date of Patent: February 19, 2013Assignee: 3M Innovative Properties CompanyInventors: Jerald K. Rasmussen, Catherine A. Bothof, Kannan Seshadri, Erin A. Satterwhite, Robert T. Fitzsimons, James I. Hembre, Mahfuza B. Ali
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Patent number: 8328023Abstract: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising cationic aminoalkyl(meth)acryloyl monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as oligonucleotides or monoclonal antibodies (MAb), from a fluid mixture.Type: GrantFiled: November 18, 2009Date of Patent: December 11, 2012Assignee: 3M Innovative Properties CompanyInventors: Douglas E. Weiss, Clinton P. Waller, Jr., Michael R. Berrigan, Andrew W. Rabins, Jeffrey A. Lucas, Kannan Seshadri, Catherine A. Bothof
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Patent number: 8329034Abstract: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising anionic monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as monoclonal antibodies (MAb), from a fluid mixture.Type: GrantFiled: June 21, 2010Date of Patent: December 11, 2012Assignee: 3M Innovative Properties CompanyInventors: Clinton P. Waller, Jr., Douglas E. Weiss, Catherine A. Bothof, Kannan Seshadri
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Publication number: 20120252091Abstract: A substrate comprising a crosslinked polymer primer layer, and grafted thereto a ligand-functionalized polymer is provided. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, and proteins, at pH's near or below the pI's of the biomaterials.Type: ApplicationFiled: January 19, 2012Publication date: October 4, 2012Inventors: Jerald K. Rasmussen, Catherine A. Bothof, Kannan Seshadri, James I. Hembre, Robert T. Fitzsimons, JR., George W. Griesgraber, Yi He