Abstract: The present disclosure provides a CD131-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain binds to or specifically binds to CD131 and neutralizes signaling by interleukin (IL) 3, IL-5 and granulocyte-macrophage colony stimulating factor (GM-CSF), and uses thereof.

Abstract: A magnetically detachable stapler device is provided that utilizes a bottom housing having a first magnetic coupling element. The first magnetic coupling element utilizes a first low friction material layer disposed thereupon. The stapler device utilizes a top housing having a coupling base structure, a magazine and a hammer. At least one of the top housing, the magazine and the hammer moves relative the coupling base structure. The coupling base structure utilizes a second magnetic coupling element which itself has a second low friction material layer disposed thereupon.

Abstract: The present application provides methods of treating late-onset Pompe disease (LOPD) using a pharmaceutical composition comprising an oligosaccharide-acid ?-glucosidase (GAA) conjugate, such as avalglucosidase alfa.

Abstract: Particles of untreated citrus byproduct consisting of dried citrus peels and pulp can be used to absorb certain useful liquid animal feed additives up to 125% of the dried peel's weight, thereby acting as an effective and efficient absorbent carrier. Stated another way, a citrus peel/liquid animal feed mix may be produced which contains up to 55% by weight liquid animal feeds, with only a 45% by weight, citrus peel carrier. The resulting mixtures are an effective and easy handling means to introduce desired commercial animal feed additives into animal feeds with a carrier that has good palatability to livestock and poultry. These mixtures are dry and free flowing.

Abstract: The present invention is directed to a system and a method to unload bulk powders from large bulk containers. The system and method are particularly useful for unloading bulk cohesive powders.

Abstract: The present invention is directed to a system and a method to unload bulk powders from large bulk containers. The system and method are particularly useful for unloading bulk cohesive powders.

Abstract: Superconducting ceramic material is woven into an interconnected structure and embedded in a polymer to produce a flexible, superconducting ceramic material. The polymer also provides protection from moisture. The ceramic polymer composite is fabricated by soaking a carbon fabric in a solution of metal nitrates, ethylene glycol and citric acid to yield a nominal composition of, for example, YBa.sub.2 Cu.sub.3 O.sub.7-x. Heat treatment results in the decomposition of the nitrates, organics and carbon fabric to produce an interconnected structure of the superconducting ceramic material which takes the shape of the original carbon fabric on a reduced scale. In addition, the processing conditions yield significant grain orientation. The superconducting grains of the ceramic material align along the direction of the original fabric weave which provides an improvement of the critical current densities.