Patents by Inventor Catherine E. O'Riordan

Catherine E. O'Riordan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PURIFICATION OF ADENOVIRUS AND AAV
    Publication number: 20100279385
    Abstract: The present invention relates to the purification of large scale quantities of active (infectious) adenovirus and AAV, especially for use in therapeutic applications. In particular, the invention provides improved methods for contacting such viruses with suitable chromatographic materials in a fashion such that any damage to the virus, particularly to surface components thereof, resulting from contact with such chromatographic materials is minimized or eliminated. The result is the ability to rapidly and efficiently purify commercial level quantities of active (infectious) virus suitable for use in therapeutic applications, e.g. gene transfer/therapy procedures.
    Type: Application
    Filed: July 16, 2009
    Publication date: November 4, 2010
    Inventors: Catherine E. O'Riordan, Amy L. Erickson (Helgerson), Alan E. Smith
  • Purification of adenovirus and AAV
    Patent number: 7579181
    Abstract: The present invention relates to the purification of large scale quantities of active (infectious) adenovirus and AAV, especially for use in therapeutic applications. In particular, the invention provides improved methods for contacting such viruses with suitable chromatographic materials in a fashion such that any damage to the virus, particularly to surface components thereof, resulting from contact with such chromatographic materials is minimized or eliminated. The result is the ability to rapidly and efficiently purify commercial level quantities of active (infectious) virus suitable for use in therapeutic applications, e.g. gene transfer/therapy procedures.
    Type: Grant
    Filed: July 12, 2005
    Date of Patent: August 25, 2009
    Assignee: Genzyme Corporation
    Inventors: Catherine E. O'Riordan, Amy L. (Ericson) Helgerson, Alan E. Smith
  • Purification of adenovirus and AAV
    Patent number: 7015026
    Abstract: The present invention relates to the purification of large scale quantities of active (infectious) adenovirus and AAV, especially for use in therapeutic applications. In particular, the invention provides improved methods for contacting such viruses with suitable chromatographic materials in a fashion such that any damage to the virus, particularly to surface components thereof, resulting from contact with such chromatographic materials is minimized or eliminated. The result is the ability to rapidly and efficiently purify commercial level quantities of active (infectious) virus suitable for use in therapeutic applications, e.g. gene transfer/therapy procedures.
    Type: Grant
    Filed: March 2, 2004
    Date of Patent: March 21, 2006
    Assignee: Genzyme Corporation
    Inventors: Catherine E. O'Riordan, Amy L. Helgerson, Alan E. Smith
  • Purification of adenovirus and AAV
    Publication number: 20040152183
    Abstract: The present invention relates to the purification of large scale quantities of active (infectious) adenovirus and AAV, especially for use in therapeutic applications. In particular, the invention provides improved methods for contacting such viruses with suitable chromatographic materials in a fashion such that any damage to the virus, particularly to surface components thereof, resulting from contact with such chromatographic materials is minimized or eliminated. The result is the ability to rapidly and efficiently purify commercial level quantities of active (infectious) virus suitable for use in therapeutic applications, e.g. gene transfer/therapy procedures.
    Type: Application
    Filed: March 2, 2004
    Publication date: August 5, 2004
    Inventors: Catherine E. O'Riordan, Amy L. Helgerson, Alan E. Smith
  • Chromatographic purification of adeno-associated virus (AAV)
    Patent number: 6143548
    Abstract: The present invention relates to the purification of large scale quantities of active (infectious) adenovirus and AAV, especially for use in therapeutic applications. In particular, the invention provides improved methods for contacting such viruses with suitable chromatographic materials in a fashion such that any damage to the virus, particularly to surface components thereof, resulting from contact with such chromatographic materials is minimized or eliminated. The result is the ability to rapidly and efficiently purify commercial level quantities of active (infectious) virus suitable for use in therapeutic applications, e.g. gene transfer/therapy procedures.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: November 7, 2000
    Assignee: Genzyme Corporation
    Inventors: Catherine E. O'Riordan, Amy E. Erickson, Alan E. Smith