Abstract: The present invention relates to a drug delivery device defining a reservoir for containing a product, having a distal end comprising an end-piece defining a channel for the transfer of the product from the reservoir, said drug delivery device comprising means for coupling said end-piece with a connector, said coupling means comprising a collar defined around a portion of the end-piece and extending from the distal end, said coupling means comprising connection means connectable to said collar, said connection means comprising a tubular wall portion having an interface defined thereon for engagement with an internal face of said collar, and a retaining hook having engagement means engageable with at least part of an external face of said collar when said connection means is connected to said collar.

Abstract: The present invention relates to a drug delivery device defining a reservoir for containing a product, having a distal end comprising an end-piece defining a channel for the transfer of the product from the reservoir, said drug delivery device comprising means for coupling said end-piece with a connector, said coupling means comprising a collar defined around a portion of the end-piece and extending from the distal end, said coupling means comprising connection means connectable to said collar, said connection means comprising a tubular wall portion having an interface defined thereon for engagement with an internal face of said collar, and a retaining hook having engagement means engageable with at least part of an external face of said collar when said connection means is connected to said collar.

Abstract: An assembly for oral administration of a medicinal product to be reconstituted from an active principle in dry or liquid form and from a diluent, A device including a prefilled syringe with said diluent, able by itself to receive a parenteral injection member is provided. A support including a body of elongate form is fastened to the syringe, the support includes a device for fixing to the syringe and, at its distal end a device for preventing the connecting of the needle to the tip of the syringe. A bottle including the active principle and a system for transferring the diluent to the active principle, then the reconstituted medicinal product from the bottle to the syringe, the transfer system being separate from the support.

Abstract: A device (1) for medical use, of the prefilled ready-to-use syringe type, comprising a tubular body (2) comprising, at its distal end (4), a tip (5) to take a needle and, at its proximal end (12), a piston (3) able to slide inside the said tubular body (2), the said piston (3) being arranged in an initial position, with respect to the tubular body (2), defining an internal working volume (8) at least partially filled with a medicinal liquid (9), the piston (3) being connected to a rod (11) for actuating the said piston, characterized in that the tubular body (2) is provided, on its internal face (13), with a means (14) of detecting the movement of the piston (3), the said means (14) being situated between the initial position of the piston and the proximal end (12) of the tubular body (2). The present invention also relates to a method for manufacturing such a device.

Abstract: The present invention relates to a shield (1) for covering at least part of a needle (2) and needle hub (6) of a needle assembly, said shield (1) having an open proximal end (1a), a closed distal end (lb) and a longitudinal wall (4) extending from said proximal end (1a) to said distal end (1b) and defining an interior cavity (5) for receiving at least part of the needle (2) and needle hub (6), characterized in that it comprises a first bulge (8) defined on said wall (4) and extending into said interior cavity (5), said first bulge (8) being designed to be able to, resiliently and releasably, engage a part of said needle assembly to secure said shield (3) thereto, said first bulge (8) further being circumferentially non-continuous about said interior cavity (5). The invention also relates to a needle assembly and to an injection device, each comprising such a shield.

Abstract: The invention relates to a shield (1) for covering at least part of a needle (2) and needle hub (6) of a needle assembly, said shield (1) having an open proximal end (1a), a closed distal end (1b) and a longitudinal wall (4) extending from said proximal end (1a) to said distal end (1b) and defining an interior cavity (5) for receiving at least part of the needle (2) and needle hub (6), characterized in that it comprises at least a first retainer (9) defined on said wall (4) and extending into said cavity (5) and, at least one second retainer (8) defined on said wall (4) and extending into said cavity (5), said annular bead portion (9) and second retainer (8) being designed to be able to, resiliently and releasably, engage a part of said needle assembly to secure said shield (3) thereto, said first retainer (9) and second retainer (8) having at least their shape or one of their dimensions different from the other.

Abstract: A device (1) for medical use, of the prefilled ready-to-use syringe type, comprising a tubular body (2) comprising, at its distal end (4), a tip (5) to take a needle and, at its proximal end (12), a piston (3) able to slide inside the said tubular body (2), the said piston (3) being arranged in an initial position, with respect to the tubular body (2), defining an internal working volume (8) at least partially filled with a medicinal liquid (9), the piston (3) being connected to a rod (11) for actuating the said piston, characterized in that the tubular body (2) is provided, on its internal face (13), with a means (14) of detecting the movement of the piston (3), the said means (14) being situated between the initial position of the piston and the proximal end (12) of the tubular body (2). The present invention also relates to a method for manufacturing such a device.

Abstract: The present invention pertains to an assembly for oral administration of a medicinal product to be reconstituted from an active principle (50) in dry or liquid form and from a diluent, characterized in that it comprises: i) a device (1) comprising: a prefilled syringe (2) with said diluent, able by itself to receive a parenteral injection member, a support (3) comprising a body (18) of elongate form which is fastened to the syringe (2), said support comprising at its proximal end (19) means (21) for fixing to the syringe (2) and, at its distal end (20), one means (24) for preventing the connecting of the parenteral injection member to the tip of the syringe (2), ii) a bottle comprising the active principle and iii) a system for transferring the diluent to the active principle, then the reconstituted medicinal product from the bottle to the syringe (2), said transfer system being separate from the support (3).

Abstract: A hypodermic syringe barrel and needle cannula assembly is provided that is capable of being dry heat sterilized at temperatures of greater than about 250° C. and up to about 350° C. in which the assembly includes a syringe barrel, a needle cannula and a bonding material, where the bonding material is stable above about 250° C., cures to provide a transparent bond, and affixes the needle cannula into the syringe barrel to provide the assembly with a post-sterilization needle pullout strength of at least about 30 newtons.

Abstract: A hypodermic syringe barrel and needle cannula assembly is provided that is capable of being dry heat sterilized at temperatures of greater than about 250° C. and up to about 350° C. in which the assembly includes a syringe barrel, a needle cannula and a bonding material, where the bonding material is stable above about 250° C., cures to provide a transparent bond, and affixes the needle cannula into the syringe barrel to provide the assembly with a post-sterilization needle pullout strength of at least about 30 newtons.