Patents by Inventor Catherine M. Cho

Catherine M. Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pentose fermentation by a recombinant microorganism
    Patent number: 9752171
    Abstract: The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: September 5, 2017
    Assignee: Codexis, Inc.
    Inventors: Ezhilkani Subbian, Xiyun Zhang, Benjamin N. Mijts, Catherine M. Cho
  • Modified native beta-ketoacyl-ACP synthases and engineered microorganisms
    Patent number: 9512447
    Abstract: Genetically engineered cells and microorganisms are provided that produce fatty alcohols and fatty acids. In particular, engineered microbial cells comprise a modified native gene having ?-ketoacyl-acp synthase activity.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: December 6, 2016
    Assignee: Codexis, Inc.
    Inventors: Smita Shankar, Louis Clark, Robert Osborne, Jonathan Vroom, Fernando Valle, Catherine M. Cho
  • MODIFIED NATIVE BETA-KETOACYL-ACP SYNTHASES AND ENGINEERED MICROORGANISMS
    Publication number: 20160010115
    Abstract: Genetically engineered cells and microorganisms are provided that produce fatty alcohols and fatty acids. In particular, engineered microbial cells comprise a modified native gene having ?-ketoacyl-acp synthase activity.
    Type: Application
    Filed: December 4, 2013
    Publication date: January 14, 2016
    Applicant: Codexis, Inc.
    Inventors: Smita Shankar, Louis Clark, Robert Osborne, Jonathan Vroom, Fernando Valle, Catherine M. Cho
  • PENTOSE FERMENTATION BY A RECOMBINANT MICROORGANISM
    Publication number: 20160010132
    Abstract: The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
    Type: Application
    Filed: September 30, 2015
    Publication date: January 14, 2016
    Inventors: Ezhilkani Subbian, Xiyun Zhang, Benjamin N. Mijts, Catherine M. Cho
  • Pentose fermentation by a recombinant microorganism
    Patent number: 9045745
    Abstract: The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: June 2, 2015
    Assignee: Codexis, Inc.
    Inventors: Ezhilkani Subbian, John H. Grate, Catherine M. Cho, Benjamin N. Mijts, Jeanne Bonomo Benoit
  • GENE SHUFFLING METHODS
    Publication number: 20150050658
    Abstract: Disclosed methods pertain to nucleic acid shuffling techniques that employ repeated short extension cycles. In each such cycle, strand extension along a template fragment is limited such that the strand extends only for a relatively short length (e.g., a few base pairs). Repeated short extension cycles cause many template switches during shuffling and thereby produce chimeric products with many crossovers. The methods may employ a pre-shuffling truncation or excision operation in which one or more parent nucleic acids has a portion of its full-length sequence truncated or excised. Shuffling with truncated parent nucleic acids introduces crossovers at the location of the truncation. Apparatus for implementing the disclosed methods may include appropriately configured thermocycling tools.
    Type: Application
    Filed: March 12, 2013
    Publication date: February 19, 2015
    Applicant: Codexix, Inc.
    Inventor: Catherine M. Cho
  • PENTOSE FERMENTATION BY A RECOMBINANT MICROORGANISM
    Publication number: 20140242674
    Abstract: The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
    Type: Application
    Filed: May 15, 2014
    Publication date: August 28, 2014
    Applicant: Codexis, Inc.
    Inventors: Ezhilkani Subbian, John H. Grate, Catherine M. Cho, Benjamin N. Mijts, Jeanne Bonomo Benoit
  • Pentose fermentation by a recombinant microorganism
    Patent number: 8778652
    Abstract: The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: July 15, 2014
    Assignee: Codexis, Inc.
    Inventors: Ezhilkani Subbian, John H. Grate, Catherine M. Cho, Benjamin Mijts, Jeanne Bonomo Benoit
  • Method for producing an alcohol using ?-glucosidase variant enzymes
    Patent number: 8715975
    Abstract: The invention provides variants of the Azospirillum irakense CelA ?-glucosidase that have improve ?-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: May 6, 2014
    Assignee: Codexis, Inc.
    Inventors: Sally Rhiannon Postlethwaite, Louis Clark, Catherine M. Cho
  • PENTOSE FERMENTATION BY A RECOMBINANT MICROORGANISM
    Publication number: 20140017765
    Abstract: The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
    Type: Application
    Filed: September 24, 2013
    Publication date: January 16, 2014
    Applicant: Codexis, Inc.
    Inventors: Ezhilkani Subbian, Xiyun Zhang, Benjamin N. Mijts, Catherine M. Cho
  • BETA-GLUCOSIDASE VARIANT ENZYMES AND RELATED POLYNUCLEOTIDES
    Publication number: 20140004586
    Abstract: The invention provides variants of the Azospirillum irakense CelA ?-glucosidase that have improve ?-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
    Type: Application
    Filed: September 5, 2013
    Publication date: January 2, 2014
    Applicant: Codexis, Inc.
    Inventors: Sally Rhiannon Postlethwaite, Louis Clark, Catherine M. Cho
  • Method of converting a biomass substrate to a fermentable sugar using a beta-glucosidase variant enzyme
    Patent number: 8530201
    Abstract: The invention provides variants of the Azospirillum irakense CelA ?-glucosidase that have improve ?-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: September 10, 2013
    Assignee: Codexis, Inc.
    Inventors: Sally Rhiannon Postlethwaite, Louis Clark, Catherine M. Cho
  • Beta-glucosidase variant enzymes and related polynucleotides
    Patent number: 8357523
    Abstract: The invention provides variants of the Azospirillum irakense CelA ?-glucosidase that have improve ?-glucosidase activity, particularly improved thermoactivity, compared to the wild type enzyme. The invention further provides related polynucleotides, vectors, host cell, and methods for making and using the variants.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: January 22, 2013
    Assignee: Codexis, Inc.
    Inventors: Sally Rhiannon Postlethwaite, Louis Clark, Catherine M. Cho
  • PENTOSE FERMENTATION BY A RECOMBINANT MICROORGANISM
    Publication number: 20130004998
    Abstract: The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
    Type: Application
    Filed: June 22, 2012
    Publication date: January 3, 2013
    Applicant: Codexis, Inc.
    Inventors: Ezhilkani Subbian, John H. Grate, Catherine M. Cho, Benjamin Mijts, Jeanne Bonomo Benoit
  • Pentose Fermentation By a Recombinant Microorganism
    Publication number: 20110294170
    Abstract: The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
    Type: Application
    Filed: May 27, 2011
    Publication date: December 1, 2011
    Applicant: CODEXIS, INC.
    Inventors: Ezhilkani Subbian, Xiyun Zhang, Benjamin Mijts, Catherine M. Cho