Patents by Inventor Cathleen A Zimmerman

Cathleen A Zimmerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8953866
    Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: February 10, 2015
    Assignee: Amnis Corporation
    Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
  • Patent number: 8824770
    Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: September 2, 2014
    Assignee: Amnis Corporation
    Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
  • Patent number: 8660332
    Abstract: Multimodal or multispectral images of cells comprising a population of cells are simultaneously collected. Photometric and/or morphometric image features identifiable in the images are used to identify differences between first and second populations of cells. The differences can include changes in a relative percentage of different cell types in each population, or a change in a first type of cell present in the first population of cells and the same type of cell in the second population of cells. The changes may be indicative of a disease state, indicative of a relative effectiveness of a therapy, or indicative of a health of the person from whom the cells populations were obtained.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: February 25, 2014
    Assignee: Amnis Corporation
    Inventors: William E. Ortyn, David A. Basiji, Philip J. Morrissey, Thaddeus C. George, Brian E. Hall, Cathleen A. Zimmerman, David J. Perry
  • Patent number: 8571294
    Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: October 29, 2013
    Assignee: Amnis Corporation
    Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael E. Seo, Phillip J. Morrissey, Cathleen A. Zimmerman
  • Patent number: 8571295
    Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: October 29, 2013
    Assignee: Amnis Corporation
    Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
  • Publication number: 20130251234
    Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Application
    Filed: March 13, 2013
    Publication date: September 26, 2013
    Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
  • Patent number: 8406498
    Abstract: Multimodal or multispectral images of cells comprising a population of cells are simultaneously collected. Photometric and/or morphometric image features identifiable in the images are used to identify differences between first and second populations of cells. The differences can include changes in a relative percentage of different cell types in each population, or a change in a first type of cell present in the first population of cells and the same type of cell in the second population of cells. The changes may be indicative of a disease state, indicative of a relative effectiveness of a therapy, or indicative of a health of the person from whom the cells populations were obtained.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: March 26, 2013
    Assignee: Amnis Corporation
    Inventors: William Ortyn, David Basiji, Philip Morrissey, Thaddeus George, Brian Hall, Cathleen Zimmerman, David Perry
  • Publication number: 20120328177
    Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Application
    Filed: April 30, 2012
    Publication date: December 27, 2012
    Applicant: AMNIS CORPORATION
    Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
  • Patent number: 8175371
    Abstract: Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: May 8, 2012
    Assignee: Amnis Corporation
    Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael E. Seo, Phillip J. Morrissey, Cathleen A. Zimmerman
  • Publication number: 20120100532
    Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Application
    Filed: November 22, 2011
    Publication date: April 26, 2012
    Applicant: AMNIS CORPORATION
    Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
  • Patent number: 8103080
    Abstract: Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Grant
    Filed: March 16, 2005
    Date of Patent: January 24, 2012
    Assignee: Amnis Corporation
    Inventors: Thaddeus C George, David A Basiji, Brian E Hall, William E Ortyn, Michael J Seo, Philip J Morrissey, Cathleen A Zimmerman
  • Publication number: 20110280467
    Abstract: Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
    Type: Application
    Filed: July 26, 2011
    Publication date: November 17, 2011
    Applicant: Amnis Corporation
    Inventors: Thaddeus C. George, David A. Basiji, Brian E. Hall, William E. Ortyn, Michael J. Seo, Philip J. Morrissey, Cathleen A. Zimmerman
  • Patent number: 7925069
    Abstract: Multimodal/multispectral images of a population of cells are simultaneously collected. Photometric and/or morphometric features identifiable in the images are used to separate the population of cells into a plurality of subpopulations. Where the population of cells includes diseased cells and healthy cells, the images can be separated into a healthy subpopulation, and a diseased subpopulation. Where the population of cells does not include diseased cells, one or more ratios of different cell types in patients not having a disease condition can be compared to the corresponding ratios in patients having the disease condition, enabling the disease condition to be detected. For example, blood cells can be separated into different types based on their images, and an increase in the number of lymphocytes, a phenomenon associated with chronic lymphocytic leukemia, can readily be detected.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: April 12, 2011
    Assignee: Amnis Corporation
    Inventors: William E. Ortyn, David A. Basiji, Philip Morrissey, Thaddeus George, Brian Hall, Cathleen Zimmerman, David Perry
  • Publication number: 20100232675
    Abstract: Multimodal or multispectral images of cells comprising a population of cells are simultaneously collected. Photometric and/or morphometric image features identifiable in the images are used to identify differences between first and second populations of cells. The differences can include changes in a relative percentage of different cell types in each population, or a change in a first type of cell present in the first population of cells and the same type of cell in the second population of cells. The changes may be indicative of a disease state, indicative of a relative effectiveness of a therapy, or indicative of a health of the person from whom the cells populations were obtained.
    Type: Application
    Filed: December 4, 2009
    Publication date: September 16, 2010
    Applicant: Amnis Corporation
    Inventors: William Ortyn, David Basiji, Philip Morrissey, Thaddeus George, Brian Hall, Cathleen Zimmerman, David Perry
  • Publication number: 20100021039
    Abstract: Multimodal/multispectral images of a population of cells are simultaneously collected. Photometric and/or morphometric features identifiable in the images are used to separate the population of cells into a plurality of subpopulations. Where the population of cells includes diseased cells and healthy cells, the images can be separated into a healthy subpopulation, and a diseased subpopulation. Where the population of cells does not include diseased cells, one or more ratios of different cell types in patients not having a disease condition can be compared to the corresponding ratios in patients having the disease condition, enabling the disease condition to be detected. For example, blood cells can be separated into different types based on their images, and an increase in the number of lymphocytes, a phenomenon associated with chronic lymphocytic leukemia, can readily be detected.
    Type: Application
    Filed: September 29, 2009
    Publication date: January 28, 2010
    Applicant: Amnis Corporation
    Inventors: William E. Ortyn, David A. Basiji, Philip Morrissey, Thaddeus George, Brian Hall, Cathleen Zimmerman, David Perry
  • Patent number: 7634126
    Abstract: Multimodal/multispectral images of a population of cells are simultaneously collected. Photometric and/or morphometric features identifiable in the images are used to separate the population of cells into a plurality of subpopulations. Where the population of cells includes diseased cells and healthy cells, the images can be separated into a healthy subpopulation, and a diseased subpopulation. Where the population of cells does not include diseased cells, one or more ratios of different cell types in patients not having a disease condition can be compared to the corresponding ratios in patients having the disease condition, enabling the disease condition to be detected. For example, blood cells can be separated into different types based on their images, and an increase in the number of lymphocytes, a phenomenon associated with chronic lymphocytic leukemia, can readily be detected.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: December 15, 2009
    Assignee: Amnis Corporation
    Inventors: William E. Ortyn, David A. Basiji, Philip Morrissey, Thaddeus George, Brian Hall, Cathleen Zimmerman, David Perry
  • Patent number: 7634125
    Abstract: Multimodal/multispectral images of a population of cells are simultaneously collected. Photometric and/or morphometric features identifiable in the images are used to separate the population of cells into a plurality of subpopulations. Where the population of cells includes diseased cells and healthy cells, the images can be separated into a healthy subpopulation, and a diseased subpopulation. Where the population of cells does not include diseased cells, one or more ratios of different cell types in patients not having a disease condition can be compared to the corresponding ratios in patients having the disease condition, enabling the disease condition to be detected. For example, blood cells can be separated into different types based on their images, and an increase in the number of lymphocytes, a phenomenon associated with chronic lymphocytic leukemia, can readily be detected.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: December 15, 2009
    Assignee: Amnis Corporation
    Inventors: William E. Ortyn, David A. Basiji, Philip Morrissey, Thaddeus George, Brian Hall, Cathleen Zimmerman, David Perry
  • Publication number: 20090190822
    Abstract: Multimodal/multispectral images of a population of cells are simultaneously collected. Photometric and/or morphometric features identifiable in the images are used to separate the population of cells into a plurality of subpopulations. Where the population of cells includes diseased cells and healthy cells, the images can be separated into a healthy subpopulation, and a diseased subpopulation. Where the population of cells does not include diseased cells, one or more ratios of different cell types in patients not having a disease condition can be compared to the corresponding ratios in patients having the disease condition, enabling the disease condition to be detected. For example, blood cells can be separated into different types based on their images, and an increase in the number of lymphocytes, a phenomenon associated with chronic lymphocytic leukemia, can readily be detected.
    Type: Application
    Filed: January 29, 2009
    Publication date: July 30, 2009
    Applicant: Amnis Corporation
    Inventors: William E. Ortyn, David A. Basiji, Philip Morrissey, Thaddeus George, Brian Hall, Cathleen Zimmerman, David Perry
  • Patent number: 7522758
    Abstract: Multimodal/multispectral images of a population of cells are simultaneously collected. Photometric and/or morphometric features identifiable in the images are used to separate the population of cells into a plurality of subpopulations. Where the population of cells includes diseased cells and healthy cells, the images can be separated into a healthy subpopulation, and a diseased subpopulation. Where the population of cells does not include diseased cells, one or more ratios of different cell types in patients not having a disease condition can be compared to the corresponding ratios in patients having the disease condition, enabling the disease condition to be detected. For example, blood cells can be separated into different types based on their images, and an increase in the number of lymphocytes, a phenomenon associated with chronic lymphocytic leukemia, can readily be detected.
    Type: Grant
    Filed: February 1, 2006
    Date of Patent: April 21, 2009
    Assignee: Amnis Corporation
    Inventors: William E. Ortyn, David A. Basiji, Philip Morrissey, Thaddeus George, Brian Hall, Cathleen Zimmerman, David Perry
  • Publication number: 20090003681
    Abstract: Multimodal/multispectral images of a population of cells are simultaneously collected. Photometric and/or morphometric features identifiable in the images are used to separate the population of cells into a plurality of subpopulations. Where the population of cells includes diseased cells and healthy cells, the images can be separated into a healthy subpopulation, and a diseased subpopulation. Where the population of cells does not include diseased cells, one or more ratios of different cell types in patients not having a disease condition can be compared to the corresponding ratios in patients having the disease condition, enabling the disease condition to be detected. For example, blood cells can be separated into different types based on their images, and an increase in the number of lymphocytes, a phenomenon associated with chronic lymphocytic leukemia, can readily be detected.
    Type: Application
    Filed: August 20, 2008
    Publication date: January 1, 2009
    Applicant: Amnis Corporation
    Inventors: William E. Ortyn, David A. Basiji, Philip Morrissey, Thaddeus George, Brian Hall, Cathleen Zimmerman, David Perry