Abstract: The present invention relates to a medical use of honokiol, and in particular to a use of honokiol in the preparation of a drug for treating a meningioma. Experiments prove that honokiol can effectively inhibit the growth of a meningioma, and eliminate and/or reduce lesions of the meningioma. Moreover, clinical experiments show that the safety and tolerance of honokiol are good.

Abstract: Disclosed herein are compounds or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof useful as G12C inhibitors, and a pharmaceutical composition comprising the same.

Abstract: A terminal and a fast charging method to fast charge the terminal, where the method includes: sending, by the terminal, instruction information to a charger connected to the terminal in order to instruct the charger to adjust an output voltage and an output current; converting, by the terminal, the output voltage of the charger into 1/K times the output voltage; and converting the output current of the charger into K times the output current such that a charging circuit between two sides of a battery charges the battery with the 1/K times the output voltage and the K times the output current, where K is a conversion coefficient of a conversion circuit with a fixed conversion ratio in the terminal and is a constant value, and K is any real number greater than one.

Abstract: Disclosed are a thin film transistor and a manufacturing method therefor, a displaying base plate and a displaying apparatus. The thin film transistor includes an active layer, a first insulating layer and a gate layer which are disposed in stack, wherein the active layer includes a source contact area, a drain contact area, and a channel area connecting the source contact area and the drain contact area; the channel area includes a first channel area, a first resistance area and a second channel area sequentially disposed in a first direction; the gate layer includes a first gate and a second gate which are separately disposed; an orthographic projection of the first gate on a plane where the active layer is located covers the first channel area; and an orthographic projection of the second gate on a plane where the active layer is located covers the second channel area.

Abstract: This disclosure provides various techniques for providing fine-grain digital and analog pixel compensation to account for voltage error across an electronic display. By employing a two-dimensional digital compensation and a local analog compensation, a fine-grain and robust pixel compensation scheme may be provided to the electronic display.

Abstract: Provided herein are Bridged Compounds having the following structures: wherein R1a, R1b, R1c, R1d, R2a, R2b, R2c, R2d, R3a, R3b, R3c, R3d, R4, R5, R6, R7, R8, m1, m2, m3, n2, n3, n4, q, X1, X2, Y1, Y2, L1 and ring A are as defined herein, compositions comprising an effective amount of a Bridged Compound, and methods for treating or preventing various diseases, e.g., pancreatic cancer, or a condition treatable or preventable by inhibition of the function of KRAS protein. In another aspect, a Bridged Compound is useful for treating or preventing a condition treatable or preventable by inhibition of the function of KRAS protein with G12D mutation. In another aspect, a Bridged Compound is useful for treating or preventing a condition treatable or preventable by inhibition of a RAS/MAPK pathway.

Abstract: Example devices are described. One example device includes a battery. The battery includes a battery charging port, a battery discharging port, a battery negative port, a protection integrated circuit, a control switch, and an electrochemical cell. The battery charging port and the battery discharging port are ports independent of each other. The battery charging port is connected to a first electrode of the electrochemical cell, and a second electrode of the electrochemical cell is connected to a first end of the control switch, and a second end of the control switch is connected to the battery negative port. The protection integrated circuit is connected in parallel to electrodes of the electrochemical cell, and the protection integrated circuit is further connected to a third end of the control switch. The battery discharging port is connected to the first electrode of the electrochemical cell.

Abstract: A displaying base plate and a manufacturing method thereof, and a displaying device. The displaying base plate includes a substrate, and a first electrode layer disposed on one side of the substrate, wherein the first electrode layer includes a first electrode pattern; a first planarization layer disposed on one side of the first electrode layer that is away from the substrate, wherein the first planarization layer is provided with a through hole, and the through hole penetrates the first planarization layer, to expose the first electrode pattern; and a second electrode layer, a second planarization layer and a third electrode layer that are disposed in stack on one side of the first planarization layer that is away from the substrate, wherein the second electrode layer is disposed closer to the substrate, the second electrode layer is connected to the first electrode pattern and the third electrode layer.

Abstract: A laminating device includes: a plate being bendable, having a resilience characteristic and for bearing the flexible substrate; a supporting base platform for supporting the plate and driving the plate and the flexible substrate on the plate to move; a bending assembly for applying stress to drive the plate and the flexible substrate on the plate to be bent towards a side, facing away from the flexible substrate, of the plate, and for releasing stress to allow the plate and the flexible substrate to rebound; and a fixing fixture for fixing the protective cover plate. The protective cover plate is used to be laminated to the flexible substrate, a shape of the fixing fixture is same as or similar to that of the protective cover plate, the fixing fixture is bent to form an accommodating space, and the protective cover plate is fixed in the accommodating space.

Abstract: Provided herein are surfactant compounds that can be used to aid in preparation of protein samples for analysis, for example by mass spectrometry.

Abstract: The disclosure herein provides bridged compounds as well as their compositions and methods of use. The compounds disclosed herein inhibit KRAS G12D activity and are useful in the treatment of various diseases including cancer.

Abstract: At least one embodiment of the present disclosure provides an oxide thin film transistor, a display device, and a preparation method of the oxide thin film transistor, and the oxide thin film transistor includes a base substrate; an oxide semiconductor layer provided on the base substrate, and an insulating layer provided on a side of the oxide semiconductor layer away from the base substrate; in which the insulating layer is made of oxide; the insulating layer includes a first insulating layer and a second insulating layer which are stacked; a density of the second insulating layer is greater than a density of the first insulating layer; and the second insulating layer is farther away from the base substrate than the first insulating layer.

Abstract: The present disclosure provides computer-aided diagnosis systems and methods. The method may include obtaining multiple medical images of one or more bones; for at least one of the multiple medical images, detecting one or more bone fracture regions of the one or more bones in the medical image; causing a management list to be displayed for managing the one or more bones; receiving an instruction related to selecting at least one of the one or more bones, the instruction being generated through the management list; and upon receiving the instruction, causing the following to be displayed: at least one of one or more reconstructed bone images related to the at least one selected bone; or a marker of the one or more detected bone fracture regions related to the at least one selected bone.

Abstract: Disclosed are a continuous rolling device and method with interfacial temperature-force controllability for a seamless metal cladding pipe. The device comprises a multi-roller skew rolling mill set, an interfacial temperature-force controlled rolling mill set and a sizing and finishing mill set sequentially distributed along a rolling axis; and the interfacial temperature-force controlled rolling mill set comprises an interface temperature control module and an interface pressure control module sequentially distributed along the rolling axis, the interface pressure control module comprises two racks and a plurality of controlled rolling rollers circumferentially and evenly distributed along the rolling axis, two ends of the controlled rolling roller are respectively mounted on the two racks through corresponding screwdown apparatuses, and the interface pressure control module realizes passive driving through a spiral pushing force or a traction force.

Abstract: Provided is a display module. The display module includes: a display panel and a heat dissipation structure; wherein the display panel includes a substrate and a display substrate layer disposed on the substrate, and the heat dissipation structure is disposed on a side, distal from the display substrate layer, of the substrate; and a gap is formed between at least a partial region of the heat dissipation structure and the substrate.

Abstract: The present disclosure relates to a system and method for extracting a region of interest. Image data in a first sectional plane may be acquired. The image data in the first sectional plane may include at least one first slice image and one second slice image. A first region of interest (ROI) in the first slice image may be determined. A second ROI in the second slice image may be determined. A first volume of interest (VOI) may be determined based on the first ROI, the second ROI, and characteristic information of the image data in the first sectional plane.

Abstract: Provided is a display panel including a plurality of sub-pixels and includes a substrate and a pixel defining layer, a light emitting device and a color film layer disposed on the substrate. The pixel defining includes M layers and M being a positive integer equal to or greater than 2, an m-th layer of pixel defining layer is covered on a surface of an (m?1)-th layer of pixel defining layer, and a refractive index nm-1 of the (m?1)-th layer of pixel defining layer is greater than a refractive index nm of the m-th layer of pixel defining layer, and wherein 2?m?M.

Abstract: An embodiment of an adaptive video encoder may include technology to determine headset-related information including at least one of focus-related information and motion-related information, and determine one or more video encode parameters based on the headset-related information. Other embodiments are disclosed and claimed.

Abstract: The present disclosure relates to the technical field of display product preparation, and in particular discloses a flexible display panel lamination device which is used for laminating a to-be-laminated flexible display panel onto a cover plate, and includes a base and an elastic lamination part arranged on the base. The elastic lamination part is provided with a first surface for bearing the to-be-laminated flexible display panel and a second surface opposite to the first surface; the second surface is symmetrically provided with two supporting protruding ribs; the two supporting protruding ribs are respectively fixed in two fixation grooves formed on the base; a gap is formed between a portion, located between the two supporting protruding ribs, of the second surface of the elastic lamination part and the base; and a portion, close to the edge, of the second surface of the elastic lamination part is supported on the base.

Abstract: A laminating device includes: a plate being bendable, having a resilience characteristic and for bearing the flexible substrate; a supporting base platform for supporting the plate and driving the plate and the flexible substrate on the plate to move; a bending assembly for applying stress to drive the plate and the flexible substrate on the plate to be bent towards a side, facing away from the flexible substrate, of the plate, and for releasing stress to allow the plate and the flexible substrate to rebound; and a fixing fixture for fixing the protective cover plate. The protective cover plate is used to be laminated to the flexible substrate, a shape of the fixing fixture is same as or similar to that of the protective cover plate, the fixing fixture is bent to form an accommodating space, and the protective cover plate is fixed in the accommodating space.