Patents by Inventor Cecile Blomquist

Cecile Blomquist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for improving the sensitivity of hybridization assays
    Patent number: 5702896
    Abstract: Methods for improving the sensitivity of hybridization assays which reduce non-specific binding (NSB) and non-specific hybridization (NSH) are disclosed. The methods include a washing method utilizing tetraalkylammonium salts at high temperatures, and release methods in which a probe-target complex is released from a solid support and recaptured. Use of both the washing and release methods results in substantial reduction in NSB and NSH without performing several rounds of release and recapture of the target nucleic acids.
    Type: Grant
    Filed: February 7, 1996
    Date of Patent: December 30, 1997
    Assignee: Amoco Corporation
    Inventors: Mark L. Collins, Cecile Blomquist, Massimo Lombardo, John Eldredge