Abstract: Disclosed are silane-based and silane-free compounds that can be used in a method for sand consolidation in a subterranean formation, sand consolidation compositions, a method for reducing water effective permeability in a subterranean formation, and water block compositions.

Abstract: A parallelepiped-shaped body has a flat top surface on which a user draws computer simulation controller buttons with a layout and spacing best fitting the user's physical needs. The user connects wires in the body to random GPIOs and maps the drawn buttons to desired game controller functions using an off-the-shelf controller connected to an MCU by pressing drawn buttons on the body along with corresponding buttons on the off-the-shelf controller, establishing which drawn button has which game controller function.

Abstract: A two-way ball valve with cryogenic seat having a valve body (1) with inlet and outlet channels (2, 2?); a ball (3) with a through-hole (3.1); and at least one closing seat (4) in one of the channels (2, 2?) with a closing sealing gasket (5) against the wall (6) of the inner cavity where the ball (3) is arranged, the gasket (5) is in contact with the ball (3), the first end (5.2) having a first annular lip (5.21) in contact with the wall (6) through a first spring (8.1) to close the fluid passage from the first channel (2), and the second end having a second annular lip (5.31) in contact with the wall (6) through a second spring (8.2) to close the fluid passage from the second channel (2?).

Abstract: A surfactant package may include an alpha olefin sulfonate primary surfactant; a betaine or sultaine co-surfactant; water; and optionally one or more solvents and/or co-solvents. A well treatment fluid may include an aqueous fluid, the surfactant package, and a friction reducer. A method of treating a portion of a subterranean formation may include introducing the well treatment fluid into a portion of the subterranean formation.

Abstract: This disclosure describes chimeric antigen receptors (CARs) engineered immune cells including the CARs, pharmaceutical compositions that include engineered immune cells that include the CARs, and methods involving such engineered immune cells.

Abstract: Computer game transmitters can shift frequencies of game assets such as audio or haptic assets to the ultrasonic range and then mix the assets with game audio, transmitting the mix. Receivers then separate the audio from the audible band to play the audio and downmix the assets for play thereof. The frequencies of the assets can be companded prior to transmission.

Abstract: There is disclosed in one example a ransomware mitigation engine, including: a processor; a convolutional neural network configured to provide file type identification (FTI) services including: identifying an access operation of a file as a write to the file or newly creating the file; computing a byte correlation factor for the file; classifying the file as belonging to a file type; determining with a screening confidence that the file type is correct for the file; determining that the screening confidence is below a screening confidence threshold; and circuitry and logic to provide heuristic analysis including: receiving notification that the confidence is below the confidence threshold; performing a statistical analysis of the file to determine a difference between an expected value and a computed value; determining from the difference, with a detection confidence, that the file has been compromised; and identifying the file as having been compromised by a ransomware attack.

Abstract: Systems and methods for tracking velocity information. One system includes an application execution server providing an application layer. The application execution server is configured to receive a request including metadata. The application execution server is also configured to generate and transmit a response to the request. The application execution server is also configured to enrich the metadata by structuring the metadata for further processing by a data processing layer, where the further processing includes determining velocity information associated with the metadata, and by supplementing the metadata with available historical velocity information. The application execution server is also configured to transmit the enriched metadata for further processing by the data processing layer.

Abstract: Methods and systems for providing configuration management using customized request headers. One system includes an electronic processor configured to receive, from a requesting device, a request including a customized request header, the customized request header including a custom configuration parameter. The electronic processor is also configured to perform a fraud analysis function based on the request. The electronic processor is also configured to generate a response including a customized response body based on the customized request header. The electronic processor is also configured to transmit the response to the requesting device, where the requesting device performs functionality based on information included in the customized response body.

Abstract: Embodiments described herein provide for structured command line input for application integration such that application programming interface (API) integration is simplified for end users. The embodiments described herein use OpenAPI specifications to map specification paths (or endpoints) to a command line interface (CLI) command structure automatically. Accordingly, the embodiments described herein enable an end user to run CLI commands within the end user's environment to accomplish application integration without the need for a technician to write configuration instructions for each type of user device. Additionally, the embodiments described herein enable efficient product integration at a larger scale as well as the ability to ad hoc add new solutions or applications based on, for example, a single line of CLI input.

Abstract: The present invention provides compositions and method for treating a subject having or suspected of having pulmonary dysfunction resulting from impaired alveolar macrophage (AM) development. The compositions comprise granulocyte-macrophage colony stimulating factor (GM-CSF) in formulations suitable for pulmonary airway administration.

Abstract: To avoid startling a computer game player immersed in virtual reality for example, active noise cancelation is gradually introduced. As an alternative, ambient noise is gradually increased to conceal loud external sounds. The noise cancelation or ambient noise generation is established according to sound exceeding a background threshold as detected by a microphone. The noise cancelation or ambient noise generation can be established according to images of a noisy object as imaged by a camera.

Abstract: Computer game developers can implicitly create haptic assets from audio assets. A low pass filter passes only audio assets with frequencies less than a threshold to a mapping module. The audio assets are then mapped to haptic assets that can be output by an ERM of a computer game controller. The haptic output can be in synchronization with play of the audio assets on speakers.

Abstract: Provided are low impact methods of creating concentrated water-in-oil and oil-in-water nanosized emulsions, effective therapeutic carriers for skin aging preparations. To achieve optimum multifunctional activity, ceramide and plant-based ceramides are selected to naturally mimic epidermal composition; and are made into evenly dispersed, small droplet, high-absorption skincare treatment emulsions. The water-in-oil emulsion is a highly stable, low-water ratio concentrate, of particular benefit to dry and aging skin types. The oil-in-water lipophilic emulsion maximizes lipid and nutrient release into the epidermis (stratum basale to stratum corneum). Lipophilic compositions are non-irritating and highly absorbable, resulting in superior skin health; specifically skin barrier keratinocyte, lipid and hydration improvements and aesthetic improvements, including skin smoothness and wrinkle reduction, while decreasing potential dermatitis and similar.

Abstract: A composition for oral mucosal delivery can include at least two terpenes having anti-inflammatory properties, the at least two terpenes comprising at least one of terpinolene, beta caryophyllene, alpha pinene, linalool, alpha-terpineol, limonene; and at least two supplements having anti-inflammatory properties, the supplements comprising at least one of cat's claw root extract and boswellia root extract. In other embodiments, the composition can contain other terpenes and active compositions/supplements that have complementary effects.

Abstract: A scent dispensing device may comprise a scent vial holder configured to hold a scent vial, a top having a plurality of openings, the plurality of openings including a scent opening and an airflow opening, a heater configured to apply heat to the scent vial, and a fan configured to cause a flow of air to pass through the airflow opening creating a difference in air pressure between the airflow opening and the scent opening such that scent from the scent vial is drawn through the scent opening and into the flow of air.

Abstract: Devices, systems and methods for providing firearms, including handguns, with infrared sights and a camera which can be held in one shooter's hand. The camera can send live video which can display a target to a portable display, such as a smart phone, smart watch or smart glasses, that is held in another hand of the shooter, so that the shooter remains out of harms' way if the target is armed. The novel sight can include hybrids of combinations of infrared and bright white visible lights, and use all visible bright white light. A motion sensor or magnetometer sensor can be separately used to cause the novel sight to become activated. Wireless charging can be accomplished with charging circuits, charging pads and USB cables and ports. A multi-position locking system can allow for a rail key to be used for spacing the novel sight at up to twelve different positions relative to the firearm.

Abstract: The present disclosure provides compositions and methods for expanding T cells or tumor infiltrating lymphocytes (TILs) in vitro. K562 feeder cells engineered to express a costimulatory molecule (e.g., 41BB ligand (41BBL)) and either interleukin 21 (IL21) or interleukin 7 (IL7) can be used in a rapid expansion protocol (REP) step to expand the T cells or TILs. Thus, provided herein is a culture comprising T-cells or TILs and modified K562 feeder cells. The T cells can be modified to express a chimeric antigen receptor (CAR) or a T cell receptor (TCR) or the TILs can be modified to express membrane-bound IL15 (mbIL15). The T cells or TILs can be expanded in vitro using aREP without the use of exogenous interleukin 2 (IL2), and the expanded cells can be used in adoptive cell therapy for treatment of cancer without concomitant use of an exogenous cytokine such as IL2.