Abstract: Devices and methods for orthodontic treatments are disclosed. An orthodontic treatment may include patient-specific aligners formed of a polymeric material and configured to rearrange a patient's teeth according to a treating clinician's treatment plan. In some embodiments, a portion of the aligner may be irradiated or otherwise exposed to a specific light treatment, which may serve to change the stiffness of that portion of the aligner. In this way, the aligner may have a non-uniform stiffness profile, which may serve to apply different forces to different teeth when stationed in a patient's mouth. Modifying the magnitude of forces applied to the teeth and more precisely tuning the spatial distribution of the forces may expedite the orthodontic treatment.