Abstract: A ready to use heterograft membrane for replacement of injured skin which is prepared by extraction of a mucous membrane from an esophagus of bovine origin. The tissue-equivalent membrane resulting from this process is applied on burns, cuts or wounds to protect the affected area and generally provide an optimum condition for the proliferation of epidermal cells. The membrane has an affinity with tissue cells and integrates to the living tissue. Afterwards, it falls off, leaving the wound area prepared for homografting, or when the epidermis has completely regenerated.