Abstract: The disclosure relates to a liquid pharmaceutical composition of aldesleukin/SDS aggregates and its use in the treatment of auto-immune disease, inflammatory disorders, gene therapies and cancer. A method for preparing said composition is also described.

Abstract: A wearable device includes a body having fasteners and a frame coupled between two fasteners. The frame includes first and second sections. A first portion of the body includes the first section of the frame and one fastener and a second portion of the body includes the second section of the frame and the other fastener. A speaker and a microphone are connected to the first portion and another speaker and another microphone are connected to the second portion. The body also includes a processor, memory accessible to the processor, and programming in the memory for configuring the processor to selectively activate the speakers and microphones such that a first speaker emits an output sound signal while a first microphone and a second speaker are deactivated and a second microphone captures an input sound signal during the emission of the output sound signal by the first speaker.

Abstract: Disclosed embodiments provide techniques for log file manipulation detection. Log file terms are identified in a set of known good log files. A frequency metric is computed for the log file terms, and one or more clusters are formed that represent the terms and their corresponding frequency metric values within the set of known good log files. New log files are then obtained from an operational computer system. The frequency metric for those terms in the new log files are computed, and checked against the established clusters. A score is computed based on how similar the new log files are to the set of known good log files by comparing the frequency metric for terms in the new log file to the data in the previously obtained cluster(s). In response to a score exceeding a predetermined threshold, one or more mitigation actions are taken.

Abstract: A method for producing an armored wall for an aircraft by determining an available thickness of the wall, an allowable areal mass of the wall, and an available space for a wall deformation due to ballistic impact. The method includes retrieving a parameterization of a plurality of armoring materials, which includes a parameter for each of a plurality of material characteristics for each of the plurality of armoring materials. The method also includes comparing the available wall thickness, the allowable areal mass, and the available deformation space with a corresponding parameter of the parameterization, selecting one armoring material for the wall from the plurality of armoring materials based on a result of comparing, and manufacturing a wall by supplementing the selected armoring material to a basic wall structure.

Abstract: This disclosure includes techniques for controlling smart home devices upon entering a home with a fingerprint sensor in a doorbell device. After capturing a fingerprint of a digit of a guest and sending the fingerprint to a server device, the server device matches the fingerprint of the digit to an entry in a guest fingerprint database for a first user. The server device sends an operational command to a smart home device separate from the doorbell device and located at a same premises as the doorbell device. In response to receiving the operational command from the server device, the smart home device performs an action corresponding to the operational command.

Abstract: This disclosure includes techniques for controlling smart home devices upon entering a home with a fingerprint sensor in a doorbell device. After capturing a fingerprint of a digit of a guest and sending the fingerprint to a server device, the server device matches the fingerprint of the digit to an entry in a guest fingerprint database for a first user. The server device sends an operational command to a smart home device separate from the doorbell device and located at a same premises as the doorbell device. In response to receiving the operational command from the server device, the smart home device performs an action corresponding to the operational command.

Abstract: This disclosure includes techniques for controlling smart home devices upon entering a home with a fingerprint sensor in a doorbell device. After capturing a fingerprint of a digit of a guest and sending the fingerprint to a server device, the server device matches the fingerprint of the digit to an entry in a guest fingerprint database for a first user. The server device sends an operational command to a smart home device separate from the doorbell device and located at a same premises as the doorbell device. In response to receiving the operational command from the server device, the smart home device performs an action corresponding to the operational command.

Abstract: Described herein are aqueous cleaning compositions comprises a combination of polyalkylenimine and an acid, a surfactant, and a solvent mixture. Methods of making and using the same are also described.

Abstract: A cleaning composition comprising: a hydrophobic polymer comprising an organoalkoxysilane; a hydrophilic polymer present in the cleaning composition in an amount ranging from 0.1% to 0.5% by weight based on the total weight of the cleaning composition; a surfactant system; and an acid. A method for cleaning a surface comprising applying the cleaning composition to the surface and retaining the cleaning composition on the surface until it dries.

Abstract: A computer-implemented method comprising, during execution of a software program comprising a procedure, determining whether an execution of the procedure satisfies a predetermined coverage criterion. In accordance with a determination that the execution of the procedure satisfies the predetermined coverage criterion, recording information related to the execution of the procedure to a log, the information based on data received from instrumented code included in the software program, and automatically generating an arrange section of a unit test for the procedure based on an initialization sequence determined from the recorded log, the initialization sequence comprising a sequence of program instructions which when executed invoke the procedure.

Abstract: Described herein are home care compositions comprising an alcohol alkoxylate surfactant and a polysaccharide gum, along with methods of making and using same.

Abstract: Disclosed are cleaning compositions including at least two anionic surfactants, such as a mixture of a linear alkylbenzene sulfonate (LAS) and a sodium lauryl ether sulfate (SLES), wherein the mixture is present in the cleaning composition in a total amount combined of LAS and SLES of about 1%-2% by weight and wherein a weight ratio of LAS:SLES is about 3:1 to about 1:1 or about 6:1 to about 4:1; an ionic agent in an amount of about 0.01% to about 0.5% by weight, a nonionic surfactant in an amount of greater than about 0% to less than about 0.45% by weight, and a fragrance. Methods of preparing and using the present cleaning compositions are also disclosed.

Abstract: A computer-implemented method comprising, during execution of a software program comprising a procedure, determining whether an execution of the procedure satisfies a predetermined coverage criterion. In accordance with a determination that the execution of the procedure satisfies the predetermined coverage criterion, recording information related to the execution of the procedure to a log, the information based on data received from instrumented code included in the software program, and automatically generating an arrange section of a unit test for the procedure based on an initialization sequence determined from the recorded log, the initialization sequence comprising a sequence of program instructions which when executed invoke the procedure.

Abstract: By individually metering and dispensing specific volumes and/or weights of each component of a dosage, an amount of the components for each dose is secured with very high accuracy. A method for dosing a pharmaceutical product in a sealed container, such as, for example, a packet, sachet, blister pack, or other unit dose form. The dosage may include a first component that is a thickening agent and a second component that is an active ingredient. The thickening agent serves as a carrier that allows the active ingredient to dissolve in the mouth and be swallowed without the administration of water. The method includes providing the first component by measuring the volume or weighing the mass of the first component and measuring the volume or weighing the mass of the second component. Subsequent components may also be individually measured or weighed before being added to a package.

Abstract: Described herein are aqueous cleaning compositions comprises a combination of polyalkylenimine and an acid, a surfactant, and a solvent mixture. Methods of making and using the same are also described.

Abstract: A cleaning composition comprising: a hydrophobic polymer comprising an organoalkoxysilane; a hydrophilic polymer present in the cleaning composition in an amount ranging from 0.1% to 0.5% by weight based on the total weight of the cleaning composition; a surfactant system; and an acid. A method for cleaning a surface comprising applying the cleaning composition to the surface and retaining the cleaning composition on the surface until it dries.

Abstract: Disclosed herein are hard surface cleaning compositions comprising, for example, a pH modifying agent in an amount sufficient to provide an alkaline pH; and a foaming system comprising: a nonionic ethoxylated/propoxylated surfactant; and a nonionic ethoxylated surfactant; wherein the concentration of the nonionic ethoxylated surfactant is greater than the concentration of the nonionic ethoxylated/propoxylated surfactant; and wherein the foaming system provides a structured network comprising a matrix having interstitial spaces. Methods of making and using these compositions are also described.

Abstract: The present invention relates to the preparation and use of copolymers composed of N-(2-hydroxypropyl) methacrylamide (HPMAA) and carboxybetaine methacrylamide (CBMAA). The invention further describes polymer brushes having structure I S—R-polymer??(I) wherein S is a substrate; R is a residue of a polymerization initiator or a RAFT agent bound to the substrate; and “polymer” is the copolymer of N-(2-hydroxypropyl) methacrylamide and carboxybetaine methacrylamide Furthermore, production of these polymer brushes, containing random or block copolymers grafted to or from a substrate is described. The copolymer brushes are suitable for protecting substrates from deposition and/or adhesion of biological substances, and/or against thrombus formation. The brushes functionalized by covalent attachment of bioactive substances to CBMAA monomer units are particularly suitable for specific interaction with target biological substances which is not affected by nonspecific deposition of non-target compounds.

Abstract: A coating having a hydrogel layer of a hydrogel of a polysaccharide and polymer brushes attached to the hydrogel layer. A process for making the coating, having the steps of: a) providing the hydrogel layer on a substrate, b) attaching an initiator having a radically transferable atom on the hydrogel layer and c) reacting monomers with the initiator to form the polymer brushes attached to the hydrogel layer.

Abstract: Disclosed herein are hard surface cleaning compositions comprising, for example, a pH modifying agent in an amount sufficient to provide an alkaline pH; and a foaming system comprising: a nonionic ethoxylated/propoxylated surfactant; and a nonionic ethoxylated surfactant; wherein the concentration of the nonionic ethoxylated surfactant is greater than the concentration of the nonionic ethoxylated/propoxylated surfactant; and wherein the foaming system provides a structured network comprising a matrix having interstitial spaces. Methods of making and using these compositions are also described.