Patents by Inventor Chanaka Mendis

Chanaka Mendis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating lethal shock induced by toxic agents and diagnosing exposure to toxic agents by measuring distinct pattern in the levels of expression of specific genes
    Publication number: 20050272055
    Abstract: A method for administering a therapeutic agent which inhibits the mechanistic pathways necessary to maintain the progression of lethal shock. The therapeutic agent is administered in the form of a drug, antisense or protein depending on the gene expression.
    Type: Application
    Filed: December 1, 2004
    Publication date: December 8, 2005
    Inventors: Rina Das, Marti Jett, Chanaka Mendis, Roger Neill
  • Method of diagnosing of exposure to toxic agents by measuring distinct pattern in the levels of expression of specific genes
    Publication number: 20030044790
    Abstract: A method of diagnosing exposure to a toxic agent comprising the steps of detecting the amount of protein/gene expression present in a sample of mammalian tissue or mammalian body fluids that has not been exposed to a toxic agent. Then the amount of protein/gene expression present in a sample of mammalian tissue or mammalian body fluids that has been exposed to the toxic agent is detected. A determination of the difference in the detected amount of protein/gene expression between the exposed and unexposed samples is made. A comparison of the difference to a library of expected protein/gene expression for predetermined toxic agents is made. Finally, an evaluation is made whether the difference indicates the exposure to a particular toxic agent. A treatment method for administering a therapeutic agent which inhibits the mechanistic pathways necessary to maintain the progression of lethal shock is also disclosed.
    Type: Application
    Filed: June 7, 2001
    Publication date: March 6, 2003
    Inventors: Rina Das, Marti Jett, Chanaka Mendis
  • Method of diagnosing of exposure to toxic agents by measuring distinct pattern in the levels of expression of specific genes
    Patent number: 6316197
    Abstract: A method of diagnosing exposure to a toxic agent comprising the steps of detecting the amount of protein/gene expression present in a sample of mammalian tissue or mammalian body fluids that has not been exposed to a toxic agent. Then the amount of protein/gene expression present in a sample of mammalian tissue or mammalian body fluids that has been exposed to the toxic agent is detected. A determination of the difference in the detected amount of protein/gene expression between the exposed and unexposed samples is made. A comparison of the difference to a library of expected protein/gene expression for predetermined toxic agents is made. Finally, an evaluation is made whether the difference indicates the exposure to a particular toxic agent. A treatment method for administering a therapeutic agent which inhibits the mechanistic pathways necessary to maintain the progression of lethal shock is also disclosed.
    Type: Grant
    Filed: February 1, 2000
    Date of Patent: November 13, 2001
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Rina Das, Marti Jett, Chanaka Mendis