Patents by Inventor Chandra Sujan SIGDEL

Chandra Sujan SIGDEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant sugar isomerase with improved activity, derived from , and production of L-gulose using the same
    Patent number: 10253341
    Abstract: The present invention relates to improving the enzymatic activity of Escherichia coli O157:H7-derived sugar isomerase by molecular mechanics and site-directed mutagenesis. More particularly, the present invention relates to a sugar isomerase having an enzymatic activity improved by mutation, a nucleic acid molecule encoding the same, a vector comprising the nucleic acid molecule, a transformant comprising the vector, a mutant of the sugar isomerase, and a method for producing L-gulose using the improved sugar isomerase.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: April 9, 2019
    Assignee: KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP.
    Inventors: Jung-Kul Lee, Chandra Sujan Sigdel, Jinglin Li, Tae-Su Kim
  • MUTANT SUGAR ISOMERASE WITH IMPROVED ACTIVITY, DERIVED FROM E. COLI, AND PRODUCTION OF L-GULOSE USING SAME
    Publication number: 20170191098
    Abstract: The present invention relates to improving the enzymatic activity of Escherichia coli O157:H7-derived sugar isomerase by molecular mechanics and site-directed mutagenesis. More particularly, the present invention relates to a sugar isomerase having an enzymatic activity improved by mutation, a nucleic acid molecule encoding the same, a vector comprising the nucleic acid molecule, a transformant comprising the vector, a mutant of the sugar isomerase, and a method for producing L-gulose using the improved sugar isomerase.
    Type: Application
    Filed: June 13, 2014
    Publication date: July 6, 2017
    Inventors: Jung-Kul LEE, Chandra Sujan SIGDEL, Jinglin LI, Tae-Su KIM