Patents by Inventor Chandresh Thakker

Chandresh Thakker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DECOUPLING YIELD AND PRODUCTIVITY OF A NON-CATABOLIC COMPOUND PRODUCED BY A HOST CELL
    Publication number: 20220307059
    Abstract: Provided herein are compositions and methods for uncoupling the yield and productivity of an isoprenoid compound produced in a host cell. In some embodiments, the yield and productivity are uncoupled by genetically modifying the host cell to reduce flux through the citric acid cycle (TCA). In other embodiments, the yield and productivity are uncoupled by reducing the levels of ATP in the host cell.
    Type: Application
    Filed: June 5, 2020
    Publication date: September 29, 2022
    Inventors: Penelope R. CHUA, Joshua Adam LERMAN, Thomas Jon SCHERBART, Chandresh THAKKER, Annie Ening TSONG, Hanxiao JIANG
  • Making C4+ products in bacteria
    Patent number: 9650654
    Abstract: Methods of making C4+ hydrocarbon feedstocks using anaerobic microbes are described.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: May 16, 2017
    Assignee: William Marsh Rice University
    Inventors: George Bennett, Chandresh Thakker
  • MAKING C4+ PRODUCTS IN BACTERIA
    Publication number: 20150376658
    Abstract: Methods of making C4+ hydrocarbon feedstocks using anaerobic microbes are described.
    Type: Application
    Filed: June 24, 2015
    Publication date: December 31, 2015
    Inventors: George BENNETT, Chandresh THAKKER
  • Increasing bacterial succinate productivity
    Patent number: 8795991
    Abstract: Improved bacteria for making succinate and other 4 carbon dicarboxylates from the Krebs cycle have modifications to reduce acetate, lactate, EtOH and formate, as well as turn on the glyoxylate shunt, produce more NADH and overexpress In one embodiment, the bacteria are ?adhE?ldhA?iclR?ack-pta plus PYC+ and NAD+-dependant FDH+.
    Type: Grant
    Filed: May 3, 2011
    Date of Patent: August 5, 2014
    Assignee: William Marsh Rice University
    Inventors: Ka-Yiu San, George Bennett, Grant Balzer, Jiangfeng Zhu, Chandresh Thakker, Ailen Sanchez
  • INCREASING BACTERIAL SUCCINATE PRODUCTIVITY
    Publication number: 20130203137
    Abstract: Improved bacteria for making succinate and other 4 carbon dicarboxylates from the Krebs cycle have modifications to reduce acetate, lactate, EtOH and formate, as well as turn on the glyoxylate shunt, produce more NADH and overexpress In one embodiment, the bacteria are ?adhE?ldhA?iclR?ack-pta plus PYC+ and NAD+-dependant FDH+.
    Type: Application
    Filed: May 3, 2011
    Publication date: August 8, 2013
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Ka-Yiu San, George N. Bennett, Grant J. Balzer, Jiangfeng Zhu, Chandresh Thakker, Ailen M. Sanchez