Abstract: Provided are an analytical method of providing an information for diagnosis of a patient who exhibits a response to preoperative chemoradiotherapy in a rectal cancer patient, wherein the expression levels of nine genes, i.e., FGFR3, GNA11, H3F3A, IL12A, IL1R1, IL2RB, NKD1, SGK2, and SPRY2 genes, is analyzed in combination, in carcinoma tissues of a rectal cancer patient, the response (susceptibility) to preoperative chemoradiotherapy can be predicted with high accuracy, and therefore the combination of said genes can be usefully applied as a biomarker for selecting a rectal cancer patient who exhibits a response to preoperative chemoradiotherapy.

Abstract: A low power output buffer circuit for outputting an Emitter Coupled Logic(ECL) signal or Pseudo ECL(PECL) signal using a CMOS device is disclosed. The prior art differential output buffer circuit is comprised of two independent output buffer circuits and each output buffer circuit utilizes 50 ohms of the load resistors, having 20 mW of current to be applied to the circuit, which requires 100 mW of total consumptive power to operate the entire circuit. According to the present invention, a simplified output buffer circuit can be constructed by connecting 100 ohms of load resistors having a center tap to ground to two pads, which reduces half of the consumptive power as compared to that in the prior art circuit.