Patents by Inventor Changlin Fu
Changlin Fu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210108217Abstract: The current invention provides a modular vector system that enables the insertion of gene expression cassettes in a recursive directional stacking fashion by rare restriction sites which requires only one type of vector. The invention also provides DNA molecules, compositions, and transgenic organisms, plants, plant tissues, plant seeds, and cells comprising recombined restriction sites for rare restriction enzymes.Type: ApplicationFiled: August 20, 2020Publication date: April 15, 2021Inventors: Changlin Fu, Jinyuan Liu
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Patent number: 10829772Abstract: The current invention provides a modular vector system that enables the insertion of gene expression cassettes in a recursive directional stacking fashion by rare restriction sites which requires only one type of vector. The invention also provides DNA molecules, compositions, and transgenic organisms, plants, plant tissues, plant seeds, and cells comprising recombined restriction sites for rare restriction enzymes.Type: GrantFiled: June 10, 2013Date of Patent: November 10, 2020Assignee: MONSANTO TECHNOLOGY LLCInventors: Changlin Fu, Jinyuan Liu
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Publication number: 20160264980Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency; enhanced cold tolerance, increased yield, enhanced-nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.Type: ApplicationFiled: January 29, 2016Publication date: September 15, 2016Inventors: Mark Scott Abad, Thomas R. Adams, Ameeta K. Agarwa, James A. Ball, Paolo Castiglioni, Banu Gopalan, Erin Bell, Shobha Char, Robert J. Bensen, Raghava S. Boddupalli, Alessandra Frizzi, Jill Deikman, Robert L. D'Ordine, Michael D. Edgerton, Xianfeng Chen, Mary Fernandes, Paul S. Chomet, Stephen Duff, Deborah G. Rucker, Changlin Fu, Jeffery E. Ahrens, Stanton B. Dotson, Richard E. Finger, Jinzhuo Dong, Molian Deng
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Publication number: 20150177244Abstract: Methods and compositions are provided for making a necrotizing enterocolitis (NEC) or sepsis assessment of an individual. Aspects of the methods include detecting a biomarker or panel of biomarkers selected from MMP7, EpCAM, and CRP. In addition, reagents, devices, systems and kits thereof that find use in practicing the subject methods are provided.Type: ApplicationFiled: December 19, 2014Publication date: June 25, 2015Inventors: Bruce Xuefeng Ling, Karl G. Sylvester, Changlin Fu, Shan Xiang Wang, Dokyoon Kim
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Publication number: 20150152428Abstract: The current invention provides a modular vector system that enables the insertion of gene expression cassettes in a recursive directional stacking fashion by rare restriction sites which requires only one type of vector. The invention also provides DNA molecules, compositions, and transgenic organisms, plants, plant tissues, plant seeds, and cells comprising recombined restriction sites for rare restriction enzymes.Type: ApplicationFiled: June 10, 2013Publication date: June 4, 2015Applicant: MONSANTO TECHNOLOGY LLCInventors: Changlin Fu, Jinyuan Liu
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Patent number: 8609614Abstract: Methods are provided for preventing or attenuating pathoangiogenic conditions by administering at least one GBS toxin receptor polypeptide or at least one immunogenic fragment thereof. Also provided are a composition that includes a GBS toxin receptor polypeptide and a method for making such a composition. In another embodiment of the invention, immunized animals also receive GBS toxin, immunocompatible antibodies to the GBS toxin receptor, and/or expanded autologous T cells to the GBS toxin receptor. Also included in this invention are methods of identifying additional GBS toxin receptors.Type: GrantFiled: February 7, 2011Date of Patent: December 17, 2013Assignee: Vanderbilt UniversityInventors: Carl G. Hellerqvist, Changlin Fu
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Patent number: 8324482Abstract: Disclosed herein are transgenic plants having recombinant DNA which expresses a G1073 transcription factor which provides enhanced resistance and/or tolerance to water deficit. More specifically the DNA constructs comprise a polynucleotide which encodes at least a functional part of a G1073 transcription factor or a homologous transcription factor.Type: GrantFiled: December 20, 2010Date of Patent: December 4, 2012Assignee: Monsanto Technology LLCInventors: Jindong Sun, Kimberly Zobrist, Jingrui Wu, Changlin Fu, Stanton B. Dotson, Linda Lutfiyya
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Publication number: 20120227131Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.Type: ApplicationFiled: September 8, 2011Publication date: September 6, 2012Inventors: Mark S. Abad, Thomas R. Adams, Ameeta K. Argarwal, James A. Ball, Paolo Castiglioni, Banu Gopalan, Erin Bell, Shobha Char, Robert J. Bensen, Raghava S. Boddupalli, Alessandra Frizzi, Jill Deikman, Robert D'Ordine, Michael D. Edgerton, Xianfeng Chen, Mary Fernandes, Paul S. Chomet, Stephen Duff, Deborah G. Rucker, Changlin Fu, Jeffrey E. Ahrens, Stanton B. Dotson, Richard E. Finger, Jinzhuo Dong, Molian Deng
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Publication number: 20110217316Abstract: Methods are provided for preventing or attenuating pathoangiogenic conditions by administering at least one GBS toxin receptor polypeptide or at least one immunogenic fragment thereof. Also provided are a composition that includes a GBS toxin receptor polypeptide and a method for making such a composition. In another embodiment of the invention, immunized animals also receive GBS toxin, immunocompatible antibodies to the GBS toxin receptor, and/or expanded autologous T cells to the GBS toxin receptor. Also included in this invention are methods of identifying additional GBS toxin receptors.Type: ApplicationFiled: February 7, 2011Publication date: September 8, 2011Applicant: Vanderbilt UniversityInventors: Carl G. Hellerqvist, Changlin Fu
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Publication number: 20110099655Abstract: Disclosed herein are transgenic plants having recombinant DNA which expresses a G1073 transcription factor which provides enhanced resistance and/or tolerance to water deficit. More specifically the DNA constructs comprise a polynucleotide which encodes at least a functional part of a G1073 transcription factor or a homologous transcription factor.Type: ApplicationFiled: December 20, 2010Publication date: April 28, 2011Applicant: MONSANTO TECHNOLOGY, LLCInventors: Jindong Sun, Kimberly Zobrist, Jingrui Wu, Changlin Fu, Stanton B. Dotson, Linda Lutfiyya
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Patent number: 7897843Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties, including increased biomass or improved cold or other osmotic stress tolerance, as compared to wild-type or reference plants. The invention also pertains to expression systems that may be used to regulate these transcription factor polynucleotides, providing constitutive, transient, inducible and tissue-specific regulation.Type: GrantFiled: June 16, 2004Date of Patent: March 1, 2011Assignee: Mendel Biotechnology, Inc.Inventors: Cai-Zhong Jiang, Jacqueline E. Heard, Oliver Ratcliffe, Neal I. Gutterson, Frederick D. Hempel, Roderick W. Kumimoto, James S. Keddie, Bradley K. Sherman, Jeffrey M. Libby, Jindong Sun, Kimberly Faye Zobrist-Duff, Jingrui Wu, Changlin Fu, Stanton B. Dotson, Linda L. Lutfiyya
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Patent number: 7888557Abstract: Disclosed herein are transgenic plants having recombinant DNA which expresses a G1073 transcription factor which provides enhanced resistance and/or tolerance to water deficit. More specifically the DNA constructs comprise a polynucleotide which encodes at least a functional part of a G1073 transcription factor or a homologous transcription factor.Type: GrantFiled: February 21, 2004Date of Patent: February 15, 2011Assignee: Monsanto Technology LLCInventors: Jindong Sun, Kimberly Zobrist, Jingrui Wu, Changlin Fu, Stanton B. Dotson, Linda Lutfiyya
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Patent number: 7754944Abstract: Synthetic modular polynucleotide constructs are useful for gene expression in plants, methods for making and using such constructs, and plants transformed with such constructs. The constructs comprise unique restriction sites for each modular element and may further comprise polynucleotide identifier sequences.Type: GrantFiled: April 2, 2007Date of Patent: July 13, 2010Assignee: Monsanto Technology LLCInventors: Changlin Fu, Brian Hauge, Vicky Gavrias
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Publication number: 20100076184Abstract: A novel GBS toxin receptor, and methods for its preparation and use are provided. GBS toxin receptor polynucleotides and polypeptides are provided as well as detection, screening, and therapeutic methods and pharmaceutical compositions involving such polynucleotides and polypeptides.Type: ApplicationFiled: June 19, 2008Publication date: March 25, 2010Applicant: Vanderbilt UniversityInventors: Carl G. Hellerqvist, Changlin Fu
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Publication number: 20090221804Abstract: Methods are provided for preventing or attenuating pathoangiogenic conditions by administering at least one GBS toxin receptor polypeptide or at least one immunogenic fragment thereof. Also provided are a composition that includes a GBS toxin receptor polypeptide and a method for making such a composition. In another embodiment of the invention, immunized animals also receive GBS toxin, immunocompatible antibodies to the GBS toxin receptor, and/or expanded autologous T cells to the GBS toxin receptor. Also included in this invention are methods of identifying additional GBS toxin receptors.Type: ApplicationFiled: December 9, 2008Publication date: September 3, 2009Applicant: Vanderbilt UniversityInventors: Carl G. Hellerqvist, Changlin Fu
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Patent number: 7410640Abstract: A novel GBS toxin receptor and methods for its preparation and use are provided. GBS toxin receptor polynucleotides and polypeptides and antibodies to GBS toxin receptor are provided, as well as detection, screening, and therapeutic methods and pharmaceutical compositions involving such polynucleotides, polypeptides and antibodies.Type: GrantFiled: April 12, 2004Date of Patent: August 12, 2008Assignee: Vanderbilt UniversityInventors: Carl G. Hellerqvist, Changlin Fu
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Publication number: 20070234442Abstract: Synthetic modular polynucleotide constructs are useful for gene expression in plants, methods for making and using such constructs, and plants transformed with such constructs. The constructs comprise unique restriction sites for each modular element and may further comprise polynucleotide identifier sequences.Type: ApplicationFiled: April 2, 2007Publication date: October 4, 2007Inventors: Changlin Fu, Brian Hauge, Vicky Gavrias
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Publication number: 20050097631Abstract: Disclosed herein are transgenic plants having recombinant DNA which expresses a G1073 transcription factor which provides enhanced resistance and/or tolerance to water deficit. More specifically the DNA constructs comprise a polynucleotide which encodes a at least a functional part of a G1073 transcription factor or a homologous transcription factor.Type: ApplicationFiled: February 21, 2004Publication date: May 5, 2005Inventors: Jindong Sun, Kimberly Zobrist, Jingrui Wu, Changlin Fu, Stanton Dotson, Linda Lutfiyya
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Publication number: 20050002931Abstract: A novel GBS toxin receptor, and methods for its preparation and use are provided. GBS toxin receptor polynucleotides and polypeptides are provided as well as detection, screening, and therapeutic methods and pharmaceutical compositions involving such polynucleotides and polypeptides.Type: ApplicationFiled: April 12, 2004Publication date: January 6, 2005Inventors: Carl Hellerqvist, Changlin Fu
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Patent number: 6803448Abstract: A novel GBS toxin receptor, and methods for its preparation and use are provided. GBS toxin receptor polynucleotides and polypeptides are provided as well as detection, screening, and therapeutic methods and pharmaceutical compositions involving such polynucleotides and polypeptides.Type: GrantFiled: July 21, 1999Date of Patent: October 12, 2004Assignee: Vanderbilt UniversityInventors: Carl G. Hellerqvist, Changlin Fu