Patents by Inventor Changling Liu
Changling Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230303545Abstract: In a synthesis method of a phenylisoxazoline compound 2-fluoro-4-chloro-5-methylaniline is used as starting material for firstly synthesizing a uracil ring, and then synthesizing an isooxazoline ring to obtain a target compound, phenylisoxazoline compound (VII), as shown in the reaction pathway below. The preparation method can be used for the synthesis of phenylisoxazoline containing uracil.Type: ApplicationFiled: June 30, 2021Publication date: September 28, 2023Inventors: Jichun YANG, Aiying GUAN, Qiao WU, Enming WU, Gongxin WU, Changling LIU
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Patent number: 11758908Abstract: Disclosed herein is a herbicidal composition, comprising an active component A and an active component B, wherein the active component B is one selected from the group consisting of glufosinate-ammonium, glufosinate-P-ammonium, oxyfluorfen, acetoflufen, imazethapyr, dimethoxamide, dimethoxamid-P, metolachlor, S-metolachlor, butachlor, acetochlor, pyroxasulfone, glyphosate and derivatives thereof.Type: GrantFiled: September 13, 2020Date of Patent: September 19, 2023Inventors: Jian Xue, DongLiang Cui, JiChun Yang, XinFeng Ren, Hui Du, AiYing Guan, Lei Dong, YanMei Zhu, ChangLing Liu
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Publication number: 20220402903Abstract: An isoxazoline compound with optical activity is shown in the formula (I). The compound of the formula (I) has excellent herbicidal activity, can be used for weeding pre- and post-emergence, and can also be used for soil treatment. The compound of the formula (I) can effectively control various broad-leaved weeds, grass weeds and Cyperaceae weeds, and can control various resistant weeds, such as glyphosate-resistant weeds. The excellent weeding effect can be obtained at a low dose. The compound has good safety to crops such as corn, wheat, rice, soybean and sugar beet. The compound can be used as a selective herbicide in crop fields in agriculture, and can also be used as a non-selective herbicide in non-cultivated land, fallow land, woodland, orchards and ridges.Type: ApplicationFiled: October 13, 2020Publication date: December 22, 2022Inventors: Jichun YANG, Aiying GUAN, Dongliang CUI, Qiao WU, Hongjuan MA, Enming WU, Changling LIU
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Patent number: 11457628Abstract: The present invention discloses a substituted pyrimidine compound. The structure is shown in general formula I. The definition of each substituent in the formula is described in the description. The compound of the present invention has broad-spectrum fungicidal, insecticidal and acaricidal activity, and has excellent control effects on cucumber downy mildew, powdery mildew, corn rust, anthrax, rice blast, aphids, Tetranychus cinnabarinus and the like.Type: GrantFiled: November 22, 2018Date of Patent: October 4, 2022Assignees: SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD., JIANGSU YANGNONG CHEMICAL CO., LTD.Inventors: Aiying Guan, Miao Li, Junfeng Wang, Leichuan Xu, Qin Sun, Xufeng Sun, Jinqiang Sun, Changling Liu
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Publication number: 20220087263Abstract: The present invention relates to a herbicidal composition and an application method thereof. The composition comprises two active components of A and B, wherein the component A is selected from a compound shown in the following general formula: The component B is selected from one of ACCase inhibitor herbicides. The herbicidal composition of the present invention is especially suitable for controlling weeds which are tolerant or resistance to organophosphorus herbicides, especially glyphosate.Type: ApplicationFiled: November 21, 2019Publication date: March 24, 2022Inventors: Dongliang CUI, Hongjuan MA, Jichun YANG, Aiying GUAN, Changling LIU, Yanmei LUO, Zhengmao LU
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Publication number: 20220039385Abstract: A herbicidal composition includes two active components of A and B. The component A is selected from a compound shown in the following formula I: The component B is selected from glyphosate and an applicable salt or ester thereof. When a solid formulation is prepared, the active component A is firstly absorbed by an absorption carrier, and the absorbed product is then mixed with the component B, auxiliaries and fillers to obtain a stable solid formulation.Type: ApplicationFiled: November 29, 2019Publication date: February 10, 2022Inventors: Jingyu CHOU, Yang LI, Yong CUI, Guangxin DONG, Shuang MI, Jichun YANG, Changling LIU
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Patent number: 11008339Abstract: Disclosed are substituted pyrazole compounds containing pyrimidinyl as shown in Formula I: The definitions of each of the substituents can be seen in the description. The compounds of present invention have a good spectrum of bactericidal, insecticidal and acaricidal activity, and have good control effect on downy mildew of cucumber, powdery mildew of wheat, corn rust, rice blast, cucumber anthracnosis and the like. The compounds of present invention also show good insecticidal activity.Type: GrantFiled: May 17, 2016Date of Patent: May 18, 2021Assignee: Shenyang Sinochem Agrochemicals R&D Co., Ltd.Inventors: Changling Liu, Aiying Guan, Junfeng Wang, Xufeng Sun, Zhinian Li, Jinbo Zhang, Lanfeng Ban, Sen Ma, Jie Lan, Xiaoli Xia, Jinlong Yang
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Publication number: 20210112813Abstract: Disclosed herein is a herbicidal composition, comprising an active component A and an active component B, wherein the active component B is one selected from the group consisting of glufosinate-ammonium, glufosinate-P-ammonium, oxyfluorfen, acetoflufen, imazethapyr, dimethoxamide, dimethoxamid-P, metolachlor, S-metolachlor, butachlor, acetochlor, pyroxasulfone, glyphosate and derivatives thereof.Type: ApplicationFiled: September 13, 2020Publication date: April 22, 2021Inventors: Jian XUE, DongLiang CUI, JiChun YANG, XinFeng REN, Hui DU, AiYing GUAN, Lei DONG, YanMei ZHU, ChangLing LIU
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Publication number: 20210015100Abstract: The present invention discloses a substituted pyrimidine compound. The structure is shown in general formula I. The definition of each substituent in the formula is described in the description. The compound of the present invention has broad-spectrum fungicidal, insecticidal and acaricidal activity, and has excellent control effects on cucumber downy mildew, powdery mildew, corn rust, anthrax, rice blast, aphids, Tetranychus cinnabarinus and the like.Type: ApplicationFiled: November 22, 2018Publication date: January 21, 2021Applicant: SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD.Inventors: Aiying GUAN, Miao LI, Junfeng WANG, Leichuan XU, Qin SUN, Xufeng SUN, Jinqiang SUN, Changling LIU
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Patent number: 10858914Abstract: The present invention discloses a silty marine natural gas hydrate gravel stimulation mining method and a mining device. The mining method appropriately relaxes the sand retention accuracy of a wellbore, so that the fine sand and muddy components of the stratum can flow into the wellbore, and after a certain period of production, the coarse gravels are injected into the extra-pipe stratum of the production well to fill the deficit caused by the production of the fine components of the stratum and the hydrates, and then the well is opened for production. The method achieves the triple objectives of improving the productivity of the silty reservoir, preventing the large-area deficit in the stratum and extending the effective period of the sand retention of the wellbore, by way of the alternation of the rounds of the gravel injection and the hydrate reservoir fluid extraction.Type: GrantFiled: April 19, 2018Date of Patent: December 8, 2020Assignee: QINGDAO INSTITUTE OF MARINE GEOLOGYInventors: Nengyou Wu, Yanlong Li, Qiang Chen, Changling Liu, Jianye Sun, Chengfeng Li, Gaowei Hu
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Patent number: 10738612Abstract: A submarine shallow hydrate exploitation device, including an exploitation unit and a collection unit. The exploitation unit includes: a submarine ship working on a seabed; a drain chamber arranged on the submarine ship, wherein a pressure valve is arranged at a top of the drain chamber, one-way drain holes are formed in a bottom of the drain chamber, and water from massive hydrates is controlled to be discharged out of the drain chamber; a high-speed spiral bit configured to mine and convey sediments; a rotary ring arranged at an inlet end of the drain chamber and configured to connect the drain chamber with the high-speed spiral bit to provide rotation power for the high-speed spiral bit; a steering arm arranged on the submarine ship and configured to realize a rotation of the high-speed spiral bit; a crusher arranged on the submarine ship and configured to crush dried massive hydrates.Type: GrantFiled: December 5, 2019Date of Patent: August 11, 2020Assignee: QINGDAO INSTITUTE OF MARINE GEOLOGYInventors: Nengyou Wu, Gaowei Hu, Changling Liu
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Publication number: 20200182055Abstract: A submarine shallow hydrate exploitation device, including an exploitation unit and a collection unit. The exploitation unit includes: a submarine ship working on a seabed; a drain chamber arranged on the submarine ship, wherein a pressure valve is arranged at a top of the drain chamber, one-way drain holes are formed in a bottom of the drain chamber, and water from massive hydrates is controlled to be discharged out of the drain chamber; a high-speed spiral bit configured to mine and convey sediments; a rotary ring arranged at an inlet end of the drain chamber and configured to connect the drain chamber with the high-speed spiral bit to provide rotation power for the high-speed spiral bit; a steering arm arranged on the submarine ship and configured to realize a rotation of the high-speed spiral bit; a crusher arranged on the submarine ship and configured to crush dried massive hydrates.Type: ApplicationFiled: December 5, 2019Publication date: June 11, 2020Applicant: Qingdao Institute of Marine GeologyInventors: Nengyou Wu, Gaowei Hu, Changling Liu
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Patent number: 10550111Abstract: The present invention relates to herbicide. Specifically to a kind of uracil compounds containing isoxazoline ring and the uses thereof. The present invention compounds have very good herbicidal activity, can effectively control weeds, such as Echinochloa crusgalli, Setaria viridis, Cyperus difformis, Juncellus serotinus, Digitaria sangunalis, Arthraxon hispidus, Abutilon theophrasti, Zinnia elegans, Amaranthus retrofluxes, Portulaca oleracea, Xanthium sibiricum, Solanum nigrum, Cassia tora, Hibiscus trionum, Glycine soja, an so on. They can effectively control weeds even at lower doses. The present invention compounds also safe to wheats, corns and rices, and can used as herbicides in agriculture fields.Type: GrantFiled: December 14, 2015Date of Patent: February 4, 2020Assignee: SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD.Inventors: Changling Liu, Jichun Yang, Hongjuan Ma, Qiao Wu, Dongliang Cui, Kecheng Yan, Miao Li
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Publication number: 20190360314Abstract: The present invention discloses a silty marine natural gas hydrate gravel stimulation mining method and a mining device. The mining method appropriately relaxes the sand retention accuracy of a wellbore, so that the fine sand and muddy components of the stratum can flow into the wellbore, and after a certain period of production, the coarse gravels are injected into the extra-pipe stratum of the production well to fill the deficit caused by the production of the fine components of the stratum and the hydrates, and then the well is opened for production. The method achieves the triple objectives of improving the productivity of the silty reservoir, preventing the large-area deficit in the stratum and extending the effective period of the sand retention of the wellbore, by way of the alternation of the rounds of the gravel injection and the hydrate reservoir fluid extraction.Type: ApplicationFiled: April 19, 2018Publication date: November 28, 2019Applicant: Qingdao Institute of Marine GeologyInventors: Changling LIU, Yanlong LI, Qiang CHEN, Nengyou WU, Jianye SUN, Chengfeng LI, Gaowei HU
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Publication number: 20180230139Abstract: The present invention relates to herbicide. Specifically to a kind of uracil compounds containing isoxazoline ring and the uses thereof. The present invention compounds have very good herbicidal activity, can effectively control weeds, such as Echinochloa crusgalli, Setaria viridis, Cyperus difformis, Juncellus serotinus, Digitaria sangunalis, Arthraxon hispidus, Abutilon theophrasti, Zinnia elegans, Amaranthus retrofluxes, Portulaca oleracea, Xanthium sibiricum, Solanum nigrum, Cassia tora, Hibiscus trionum, Glycine soja, an so on. They can effectively control weeds even at lower doses. The present invention compounds also safe to wheats, corns and rices, and can used as herbicides in agriculture fields.Type: ApplicationFiled: December 14, 2015Publication date: August 16, 2018Applicant: SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTDInventors: Changling LIU, Jichun YANG, Hongjuan MA, Qiao WU, Dongliang CUI, Kecheng YAN, Miao LI
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Publication number: 20180141961Abstract: Disclosed are substituted pyrazole compounds containing pyrimidinyl as shown in Formula I: The definitions of each of the substituents can be seen in the description. The compounds of present invention have a good spectrum of bactericidal, insecticidal and acaricidal activity,and have good control effect on downy mildew of cucumber, powdery mildew of wheat, corn rust, rice blast, cucumber anthracnosis and the like. The compounds of present invention also show good insecticidal activity.Type: ApplicationFiled: May 17, 2016Publication date: May 24, 2018Inventors: Changling Liu, Aiying Guan, Junfeng Wang, Xufeng Sun, Zhinian Li, Jinbo Zhang, Lanfeng Ban, Sen Ma, Jie Lan, Xiaoli Xia, Jinlong Yang
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Applications of substituent benzyloxy group containing ether compounds for preparing antitumor drugs
Patent number: 9895346Abstract: Disclosed are applications of substituent benzyloxy group containing ether compounds represented by general formula I for preparing antitumor drugs. The definition of the substituent groups in the formula I are provided in the specification. The compounds having general formula I have desirable antitumor activity, particularly, and have excellent activity against leukemia strain HL-60, lung cancer A549, H157, H460, H520, bladder cancer T24, J82, prostate cancer LNCap, PC-3, rectal cancer HCT8, HCT116, RkO and the like.Type: GrantFiled: August 22, 2014Date of Patent: February 20, 2018Assignees: Sinochem Corporation, Shenyang Research Institute of Chemical Industry Co., Ltd.Inventors: Changling Liu, Aiying Guan, Xiaoping Yang, Baoshan Chai -
Patent number: 9897529Abstract: The present invention disclosures a test system and test method for a simulation experiment of gas hydrate in a porous medium. The test system comprises a reactor, a sensor system, a hardware interface apparatus and a data processing system; the reactor is used for containing tested medium, the sensor system is mounted inside the reactor, and the sensor system is connected to the data processing system through the hardware interface apparatus; the test method comprises a procedure of experiment and measurement data acquisition, and a procedure of analyzing and processing measurement signals; by establishing of electrical model I, acoustic model II and the fused model III, realizing the simulation of the synthesis/decomposition processes of gas hydrate in the deposits in laboratory environment and implementation of the acoustic and electrical parameters combined test, an accurate gas hydrate saturation calculation model can be established at last.Type: GrantFiled: September 12, 2016Date of Patent: February 20, 2018Assignee: CHINA UNIVERSITY OF PETROLEUM (EAST CHINA)Inventors: Lanchang Xing, Changling Liu, Qiang Chen, Yanfeng Geng, Chenquan Hua, Yu Qi
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Applications of Substituent Benzyloxy Group Containing Ether Compounds for Preparing Antitumor Drugs
Publication number: 20170296508Abstract: Disclosed are applications of substituent benzyloxy group containing ether compounds represented by general formula I for preparing antitumor drugs. The definition of the substituent groups in the formula I are provided in the specification. The compounds having general formula I have desirable antitumor activity, particularly, and have excellent activity against leukemia strain HL-60, lung cancer A549, H157, H460, H520, bladder cancer T24, J82, prostate cancer LNCap, PC-3, rectal cancer HCT8, HCT116, RkO and the like.Type: ApplicationFiled: August 22, 2014Publication date: October 19, 2017Inventors: Changling Liu, Aiying Guan, Xiaoping Yang, Baoshan Chai -
Publication number: 20170292904Abstract: The present invention disclosures a test system and test method for a simulation experiment of gas hydrate in a porous medium. The test system comprises a reactor, a sensor system, a hardware interface apparatus and a data processing system; the reactor is used for containing tested medium, the sensor system is mounted inside the reactor, and the sensor system is connected to the data processing system through the hardware interface apparatus; the test method comprises a procedure of experiment and measurement data acquisition, and a procedure of analyzing and processing measurement signals; by establishing of electrical model I, acoustic model II and the fused model III, realizing the simulation of the synthesis/decomposition processes of gas hydrate in the deposits in laboratory environment and implementation of the acoustic and electrical parameters combined test, an accurate gas hydrate saturation calculation model can be established at last.Type: ApplicationFiled: September 12, 2016Publication date: October 12, 2017Inventors: LANCHANG XING, CHANGLING LIU, QIANG CHEN, YANFENG GENG, CHENQUAN HUA, YU QI