Patents by Inventor Changqing Lin

Changqing Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240087628
    Abstract: A multi-resistance-state spintronic device, including: a top electrode and a bottom electrode respectively connected to a read-write circuit; and a magnetic tunnel junction between two electrodes. The magnetic tunnel junction includes from top to bottom: a ferromagnetic reference layer, a barrier tunneling layer, a ferromagnetic free layer, and a spin-orbit coupling layer. Nucleation centers are provided at two ends of the ferromagnetic free layer to generate a magnetic domain wall; the spin-orbit coupling layer is connected to the bottom electrode, and when a write pulse is applied, an electron spin current is generated and drives the magnetic domain wall through a spin-orbit torque to move; a plurality of local magnetic domain wall pinning centers are provided at an interface between the spin-orbit coupling layer and the ferromagnetic free layer to enhance a strength of a DM interaction constant between interfaces.
    Type: Application
    Filed: December 30, 2020
    Publication date: March 14, 2024
    Inventors: Guozhong XING, Huai LIN, Feng ZHANG, Di WANG, Long LIU, Changqing XIE, Ling LI, Ming LIU
  • Publication number: 20240071451
    Abstract: The three-state spintronic device includes: a bottom electrode, a magnetic tunnel junction and a top electrode from bottom to top. The magnetic tunnel junction includes: a spin-orbit coupling layer, a ferromagnetic free layer, a barrier tunneling layer, a ferromagnetic reference layer, three local magnetic domain wall pinning centers and domain wall nucleation centers. An antisymmetric exchange interaction is modulated, and the magnetic domain wall pinning centers are embedded in an interface between a heavy metal and the ferromagnetic free layer. The magnetic domain wall nucleation centers are at two ends of the ferromagnetic free layer. A current pulse flows through the spin-orbit coupling layer to generate a spin current and the spin current is injected into the ferromagnetic free layer. Under a control of all-electrical controlled, an effective field of a spin-orbit torque drives domain wall to move and displace.
    Type: Application
    Filed: January 21, 2021
    Publication date: February 29, 2024
    Inventors: Huai LIN, Guozhong XING, Zuheng WU, Long LIU, Di WANG, Cheng LU, Peiwen ZHANG, Changqing XIE, Ling LI, Ming LIU
  • Publication number: 20230021840
    Abstract: Embodiments of the present invention relate to use of a GP73 inhibitor in preparation of a drug for treating diabetes. In the embodiments of the present invention, the inventor finds that GP73 plays a key role in blood glucose regulation, and in particular, finds that soluble GP73 can specifically bind to glucagon to form a complex, enhances the blood glucose-rising function and gluconeogenesis function of glucagon and prolongs the half-life of glucagon; and finds soluble GP73 can activate the glucose production in liver and/or kidney and a gluconeogenesis signaling pathway in a glucagon-independent manner. Based on the blood glucose regulation effect of the GP73 described above, the inventor also proves through animal experiments: the GP73 inhibitor can reduce the blood glucose level and glycated hemoglobin level of diabetic mice and have a protective effect on islet ? cells, and thereby having the effect of treating diabetes.
    Type: Application
    Filed: September 7, 2022
    Publication date: January 26, 2023
    Inventors: Changqing LIN, Zhiwei SUN, Qi GAO, Shuang QIE, Lei XU, JING LI, Jianbo LIN, Hengqi ZHU, Fei ZHENG, Xuechao LIU
  • Publication number: 20220372173
    Abstract: The present invention provides a lectin-magnetic carrier coupling complex for separating glycosylated exosomes from a clinical sample. The lectin-magnetic carrier coupling complex comprises a magnetic carrier and lectins coupled to the outer side of the magnetic carrier. The lectin-magnetic carrier coupling complex provided by the present invention may rapidly, accurately, and automatically separate glycosylated exosomes from a clinical sample with a high separation efficiency; and the separated exosomes are intact in morphology without rupturing or cracking, may be directly used for liquid detection of glycosylated exosomes, or directly used for immunology-related detection, or directly used for nucleotide sequence detection and analysis after extracting nucleic acids from the exosomes.
    Type: Application
    Filed: July 13, 2022
    Publication date: November 24, 2022
    Inventors: Changqing LIN, Tiansheng CHEN, Kun HAO, He HUANG, Qi GAO, Yanzhao LI, Zhihui XU, Shuang QIE, Guangzhen ZHAO
  • Publication number: 20220349901
    Abstract: The present invention relates to a lectin-macromolecular carrier coupling complex for separating glycosylated exosomes from a clinical sample, which comprises a macromolecular carrier and lectins coupled to the outer side of the macromolecular carrier. The complex may simply, conveniently, rapidly, and accurately separate glycosylated exosomes from a clinical sample with a high separation efficiency and a good repeatability; and the separated exosomes are intact in morphology without rupturing or cracking, may be directly used for liquid detection of glycosylated exosomes, or directly used for immunology-related detection, or directly used for gene detection or analysis after extracting related nucleic acids from the exosomes.
    Type: Application
    Filed: July 14, 2022
    Publication date: November 3, 2022
    Inventors: Changqing LIN, Tiansheng CHEN, Kun HAO, He HUANG, Qi GAO, Yanzhao LI, Zhihui XU, Shuang QIE, Guangzhen ZHAO
  • Publication number: 20220017071
    Abstract: Disclosed are a self-adaptive assistance control device, a computer device and a storage medium for vehicle passing curve. The method comprises: step S10, according to signals from vehicle's sensors, identifying current bend types, and obtaining, corresponding to bend types, a lateral impact degree of the current vehicle according to a lateral acceleration; step S11, obtain an expected longitudinal acceleration based on the lateral impact degree; step S12, according to the expected longitudinal acceleration and a current actual longitudinal acceleration, determining an activation type for current bend assist control; and step S13, according to the activation type, cooperatively controlling an engine torque or/and an ESC braking intensity, so as to realize expected longitudinal control over the vehicle in the road curve.
    Type: Application
    Filed: January 28, 2019
    Publication date: January 20, 2022
    Inventors: XINGTAI MEI, CHENG DENG, CHUANSHUAI MA, CHANGQING LIN, QIN LI, QI ZENG
  • Patent number: 11067579
    Abstract: A novel serological target marker GP73 used for diagnosing and identifying a simple fatty liver and steatohepatitis in populations with fatty liver and a detection application method thereof. The serological target marker GP73 and the application thereof can replace golden standard liver puncture to identify and diagnose the simple fatty liver and steatohepatitis in populations with fatty liver, reduce the detection pain of a patient, and have an extremely high clinical application value in clinically identifying and diagnosing the simple fatty liver and steatohepatitis in the populations with fatty liver and assisting the treatment of the simple fatty liver and steatohepatitis.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: July 20, 2021
    Assignees: BEIJING DITAN HOSPITAL CAPITAL MEDICAL UNIVERSITY, BEIJING HOTGEN BIOTECH CO., LTD
    Inventors: Hongshan Wei, Boan Li, Changqing Lin, Yong Qiao
  • Patent number: 10853030
    Abstract: The present disclosure provides an input method and device. The method specifically comprises: displaying an input interface, where the input interface includes at least one key; in response to a touch operation of a key by a user in an input process, playing an audio corresponding to the key and matching the characteristics of the input interface. Based on keystroke by the user in the input process, the disclosed embodiments provide feedback to the user with animation effect and dynamic audio matching a theme of the current input interface, and enhance key tones in the input process.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: December 1, 2020
    Assignee: BEIJING SOGOU TECHNOLOGY DEVELOPMENT CO., LTD.
    Inventor: Changqing Lin
  • Patent number: 10845887
    Abstract: The present disclosure provides a key processing method and apparatus, and an apparatus for key processing. The key processing method specifically includes processing a non-triggered key in response to a triggering operation by a user on a current key in a current interface where the non-triggered key is a key in the current interface other than the current key, and outputting a processing result of the non-triggered key. The embodiments of the present disclosure not only enrich the current interface, but also enhance the feedback effectiveness and user experience during the use of the interface. Thus, the accuracy of the key operation may be improved.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: November 24, 2020
    Assignee: BEIJING SOGOU TECHNOLOGY DEVELOPMENT CO., LTD.
    Inventor: Changqing Lin
  • Patent number: 10697040
    Abstract: A continuous annealing method for low coercive force cold-rolled electromagnetic pure iron plate and strip. Control parameters of each stages in a continuous annealing process are as follows: 750-850° C. at a heating stage; 750-850° C. at a soaking stage, the soaking time is 100-150 s; an outlet temperature of 575-675° C. at a slow-cooling stage, the cooling speed in slow-cooling stage is 2.5-10° C./s; an outlet temperature of 380-420° C. at a fast-cooling stage, the cooling speed of the fast-cooling stage is 15-25° C./s; and 270-310° C. at an overaging stage. The annealing medium is a non-oxidizing atmosphere composed of H2 and N2. After annealing, the cold-rolled electromagnetic pure iron plate and strip is leveled and pressed such that the leveling elongation rate of the plate and strip is controlled within the range of 0.2±0.1%.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: June 30, 2020
    Assignee: BAOSHAN IRON & STEEL CO., LTD.
    Inventors: Yuanyuan Yan, Gaofei Liang, Guoping Cheng, Changqing Lin
  • Patent number: 10329335
    Abstract: Disclosed are a composition and system for separating and detecting an alpha-fetoprotein variant, comprising a separation reagent and a detection reagent; a system for separating and detecting an alpha-fetoprotein variant and a use thereof; and a kit for separating and detecting the alpha-fetoprotein variant. By means of the composition and system for separating and detecting the alpha-fetoprotein variant, and the use thereof, primary liver cancer can be indicated early on, the sensitivity is high, and the method is rapid, simple and automated.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: June 25, 2019
    Assignee: BEIJING HOTGEN BIOTECH CO., LTD.
    Inventors: Haifeng Luo, Boan Li, Changqing Lin
  • Publication number: 20190033983
    Abstract: The present disclosure provides a key processing method and apparatus, and an apparatus for key processing. The key processing method specifically includes processing a non-triggered key in response to a triggering operation by a user on a current key in a current interface where the non-triggered key is a key in the current interface other than the current key, and outputting a processing result of the non-triggered key. The embodiments of the present disclosure not only enrich the current interface, but also enhance the feedback effectiveness and user experience during the use of the interface. Thus, the accuracy of the key operation may be improved.
    Type: Application
    Filed: December 15, 2016
    Publication date: January 31, 2019
    Inventor: Changqing LIN
  • Publication number: 20180265945
    Abstract: A continuous annealing method for low coercive force cold-rolled electromagnetic pure iron plate and strip. Control parameters of each stages in a continuous annealing process are as follows: 750-850° C. at a heating stage; 750-850° C. at a soaking stage, the soaking time is 100-150 s; an outlet temperature of 575-675° C. at a slow-cooling stage, the cooling speed in slow-cooling stage is 2.5-10° C./s; an outlet temperature of 380-420° C. at a fast-cooling stage, the cooling speed of the fast-cooling stage is 15-25° C./s; and 270-310° C. at an overaging stage. The annealing medium is a non-oxidizing atmosphere composed of H2 and N2. After annealing, the cold-rolled electromagnetic pure iron plate and strip is leveled and pressed such that the leveling elongation rate of the plate and strip is controlled within the range of 0.2±0.1%.
    Type: Application
    Filed: September 1, 2016
    Publication date: September 20, 2018
    Inventors: Yuanyuan YAN, Gaofei LIANG, Guoping CHENG, Changqing LIN
  • Publication number: 20180225087
    Abstract: The present disclosure provides an input method and device. The method specifically comprises: displaying an input interface, where the input interface includes at least one key; in response to a touch operation of a key by a user in an input process, playing an audio corresponding to the key and matching the characteristics of the input interface. Based on keystroke by the user in the input process, the disclosed embodiments provide feedback to the user with animation effect and dynamic audio matching a theme of the current input interface, and enhance key tones in the input process.
    Type: Application
    Filed: March 22, 2016
    Publication date: August 9, 2018
    Inventor: Changqing LIN
  • Publication number: 20180009863
    Abstract: Disclosed are a composition and system for separating and detecting an alpha-fetoprotein variant, comprising a separation reagent and a detection reagent; a system for separating and detecting an alpha-fetoprotein variant and a use thereof; and a kit for separating and detecting the alpha-fetoprotein variant. By means of the composition and system for separating and detecting the alpha-fetoprotein variant, and the use thereof, primary liver cancer can be indicated early on, the sensitivity is high, and the method is rapid, simple and automated.
    Type: Application
    Filed: December 30, 2015
    Publication date: January 11, 2018
    Inventors: Haifeng LUO, Boan LI, Changqing LIN
  • Publication number: 20050181269
    Abstract: The present invention relates to a microfibrous fuel cell structure of elongated form with a longitudinal axis. Such microfibrous fuel cell comprises electrocatalyst layers supported by a fiber network formed of unidirectional or substantially unidirectional conductive fibers. The conductive fibers of such fiber network are oriented parallelly or substantially parallelly to the longitudinal axis of the fuel cell, therefore allowing such fiber network to conform to the curvature of the microfibrous fuel cell along the radial direction but without causing overbending of the individual fibers.
    Type: Application
    Filed: January 6, 2005
    Publication date: August 18, 2005
    Inventors: Ray Eshraghi, Changqing Lin, Jung-Chou Lin, Martin Ketterer
  • Publication number: 20040058224
    Abstract: This invention relates to a microfibrous fuel cell having at least one high quality electrocatalyst layer of a dual-layer structure, i.e., a catalyst layer comprising a catalytic material, and an interfacial composition layer comprising a mixture of catalytic material and electrolyte medium. Said high quality electrocatalyst layer can be formed by various catalyzation methods, including diffusion catalyzation, ion-exchange catalyzation, electrodeposition catalyzation, impregnation catalyzation, chemical deposition catalyzation, and alternating catalyst/electrolyte addition catalyzation. The present invention also relates to a fuel cell assembly comprising multiple such microfibrous fuel cells bundled together, and methods for in situ catalyzation of such fuel cell assembly to form high quality electrocatalyst layers of such dual-layer structure.
    Type: Application
    Filed: September 24, 2002
    Publication date: March 25, 2004
    Inventors: Ray R. Eshraghi, Jung-Chou Lin, Changqing Lin, Michael W. Riley, Erik K. Yarbrough