Patents by Inventor Changsheng Liu
Changsheng Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11978910Abstract: Provided are an electrode assembly, a battery cell, a battery, and an electrical device. The electrode assembly includes first electrode plates and a second electrode plate that are of opposite polarities. The second electrode plate and two first electrode plates are stacked and wound to form the electrode assembly. The second electrode plate is located between the two first electrode plates. Each of the first electrode plates includes a first composite current collector and a first active material layer. The first active material layer is disposed on a surface that is of the first composite current collector and that is oriented back from the second electrode plate. The first composite current collector is configured to dielectrically isolate the first active material layer from the second electrode plate and allow passage of ions transmitted between the first active material layer and the second electrode plate.Type: GrantFiled: September 21, 2023Date of Patent: May 7, 2024Assignee: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITEDInventors: Changsheng He, Mingjian Liu, Keqiang Li, Xiaosong Liu, Bin Xie, Zhiyang Wu
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Publication number: 20240088362Abstract: An electrode plate, an electrode assembly, and a secondary battery are provided. The electrode plate includes a current collector, an active material layer arranged on one surface of the current collector, and an electrical connection member electrically connected to the current collector. The active material layer is arranged on a main body portion of the current collector, the electrical connection member and the current collector are connected to each other by welding at an edge of the current collector, the welding connection region is referred to as a transfer welding region, and the current collector includes a support layer and an electrically conductive layer arranged on one surface of the support layer. The electrode plate further includes a first insulation layer arranged on a further surface of the current collector and covering at least the entirety of the transfer welding region when viewed in a thickness direction of the electrode plate.Type: ApplicationFiled: November 22, 2023Publication date: March 14, 2024Applicant: CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITEDInventors: Zhiyang WU, Changsheng HE, Keqiang LI, Xiaosong LIU
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Publication number: 20230414262Abstract: The present invention relates to a high-strength absorbable composite active internal fixation device and a preparation method therefor. Specifically, the present invention discloses the internal fixation device and its preparation method, which possess excellent biological activity and mechanical properties.Type: ApplicationFiled: March 2, 2021Publication date: December 28, 2023Inventors: Changsheng LIU, Yulin LI, Wei LUO, Can CHEN
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Publication number: 20230091503Abstract: The present invention relates to a preparation method for a microneedle patch. Specifically, the present invention provides a preparation method for a microneedle patch, and the method comprises steps: (1) milling a base into a master mold of the microneedle patch; (2) conducting surface treatment on the master mold, to obtain the treated master mold; (3) conducting reverse molding on a surface of the treated master mold, conducting deaeration, curing, and demolding, to obtain the cured daughter mold; and (4) casting the modification solution on the surface of the daughter mold, and then conducting deaeration, drying and curing, to obtain the microneedle patch. The method for preparing the microneedle patch in the present invention can greatly reduce the milling difficulty, and save the milling cost and time. The microneedle molds with different aspect ratios, areas and shapes can also be prepared as required, following with reverse molding to diverse microneedle patches.Type: ApplicationFiled: November 18, 2022Publication date: March 23, 2023Inventors: Changsheng Liu, Hongyan He, Lili Jin, Dian Zhang
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Patent number: 11574122Abstract: Embodiments of the disclosure provide systems and methods for processing unstructured texts in a medical record. A disclosed system includes at least one processor configured to determine a plurality of word representations of an unstructured text and tag entities in the unstructured text by performing a named entity recognition task on the plurality of word representations. The at least one processor is further configured to determine position embeddings based on positions of words in the unstructured text relative to positions of the tagged entities and concatenate the plurality of word representations with the position embeddings. The at least one processor is also configured to determine relation labels between pairs of tagged entities by performing a relationship extraction task on the concatenated word representations and position embeddings.Type: GrantFiled: August 19, 2019Date of Patent: February 7, 2023Assignee: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATIONInventors: Feng Gao, Changsheng Liu, Yue Pan, Youbing Yin, Kunlin Cao, Qi Song
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Publication number: 20220106568Abstract: Disclosed are a stem cell generator, a construction method therefor and the use thereof. The stem cell generator is formed by implanting a biomaterial loaded with active substances and/or cells, or a biomaterial with an osteogenic induction capability into animal or human bodies and producing organoids upon development.Type: ApplicationFiled: January 21, 2020Publication date: April 7, 2022Inventors: Changsheng LIU, Kai DAI, Jing WANG, Qinghao ZHANG, Shunshu DENG, Guilong LI
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Publication number: 20220040380Abstract: Disclosed is a stem cell generator for the generation of organoids after the development of biological materials loaded with active substances which are implanted into an animal or a human body. The active substances are mesenchymal stem cells, bone morphogenetic protein-2 or bone morphogenesis protein-7, other growth factors/polypeptides or growth factors/polypeptide combinations having the ability of inducing bone regeneration, or combinations thereof. The stem cell generator contains various types of blood cells and hematopoietic progenitor/stem cells having complete functions. The produced stem cells are used for treating hematopoietic damage, and can treat bone marrow failure and leukemia caused by radiotherapy/chemotherapy.Type: ApplicationFiled: January 21, 2020Publication date: February 10, 2022Inventors: Changsheng LIU, Kai DAI, Jing WANG, Guilong LI, Qinghao ZHANG, Shunshu DENG
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Publication number: 20220040379Abstract: Disclosed is a new use of a stem cell generator in preparation of bone defect repair materials, wherein the stem cell generator is formed by implanting a biomaterial with osteogenic induction capability or a biomaterial loaded with active substances and/or cells into an animal or a human body and generating organoids after development, the active substances are bone morphogenetic protein-2, or bone morphogenetic protein-7, other growth factors/polypeptides having bone regeneration induction ability, growth factors/polypeptide combinations, or a combination thereof. The cells are bone marrow-derived mesenchymal stem cells, adipose-derived mesenchymal stem cells or other derived mesenchymal stem cells; other types of cells with osteogenic differentiation capability; cells that aid in osteogenic differentiation of mesenchymal stem cells, such as vascular endothelial cells and the like.Type: ApplicationFiled: January 21, 2020Publication date: February 10, 2022Inventors: Changsheng LIU, Kai DAI, Jing WANG, Shunshu DENG
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Publication number: 20210017554Abstract: An enzymatic method for selective catalytic preparation of 4-octyl itaconate is provided, which belongs to the fields of biochemical engineering and enzymatic catalysis. The method uses a lipase or an enzyme preparation with a catalytic triplet structure (Ser-His-Asp or Ser-His-Gly) as a catalyst, itaconic acid and n-octanol or n-octanol-derived ester as raw materials to selectively catalyze the synthesis of 4-octyl itaconate in a solvent system or a solvent-free system. Compared with chemical synthesis routes of 4-octyl itaconate, the present method has the advantages of green, safety, and environmental protection. The obtained 4-octyl itaconate is one of the new small molecule compounds with anti-inflammatory and anti-viral properties.Type: ApplicationFiled: September 29, 2020Publication date: January 21, 2021Inventors: Li DENG, Changsheng LIU, Fang WANG
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Publication number: 20200065374Abstract: Embodiments of the disclosure provide systems and methods for processing unstructured texts in a medical record. A disclosed system includes at least one processor configured to determine a plurality of word representations of an unstructured text and tag entities in the unstructured text by performing a named entity recognition task on the plurality of word representations. The at least one processor is further configured to determine position embeddings based on positions of words in the unstructured text relative to positions of the tagged entities and concatenate the plurality of word representations with the position embeddings. The at least one processor is also configured to determine relation labels between pairs of tagged entities by performing a relationship extraction task on the concatenated word representations and position embeddings.Type: ApplicationFiled: August 19, 2019Publication date: February 27, 2020Applicant: SHENZHEN KEYA MEDICAL TECHNOLOGY CORPORATIONInventors: Feng Gao, Changsheng Liu, Yue Pan, Youbing Yin, Kunlin Cao, Qi Song
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Publication number: 20190107730Abstract: An imaging system including an image processor and a lens module coupled to the image processor. The lens module includes a polarizer, a lens, and a photosensitive sensor. The polarizer has a polarization angle and filters light according to the polarization angle. The lens is arranged adjacent to the polarizer to receive the light filtered through the polarizer. The photosensitive sensor is arranged adjacent to the lens. The photosensitive sensor can sense light to generate image information. The image processor can obtain information of polarized light according to the image information of an image and to generate a target image.Type: ApplicationFiled: October 10, 2018Publication date: April 11, 2019Inventors: Changsheng LIU, Fan ZHANG
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Patent number: 9832395Abstract: The present application describes an information processing method for solving a technical problem of low efficiency in an electronic device. The method includes capturing the first image by a first image capturing unit among at least two image capturing units, and at the same time, capturing a second image by a second image capturing unit among the at least two image capturing units, where the first image and the second image correspond to the same captured object; such that the pixels in the first image is less than those in the second image; transmitting the first image and the second image to an image processing unit; in the process of transmitting the second image, determining a processing way according to at least one characteristic parameter information corresponding to the first image by the image processing unit.Type: GrantFiled: September 29, 2014Date of Patent: November 28, 2017Assignee: LENOVO (BEIJING) CO., LTD.Inventors: Wenbin Song, Changsheng Liu, Yuru Jin
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Patent number: 9593151Abstract: Disclosed is the use of a fusion protein in drugs for stimulating differentiation of bone marrow mesenchymal stem cells to hematopoietic stem/progenitor cells, or drugs for proliferation of granulocyte hematopoietic progenitor cells. The fusion protein has a sequence as shown in SEQ ID NO: 2 or SEQ ID NO: 4. The drugs can be used for the prevention and/or treatment of (i) hematopoietic dysfunction caused by chemotherapy, (ii) hematopoietic dysfunction caused by radiotherapy, or (iii) leukopenia.Type: GrantFiled: December 5, 2013Date of Patent: March 14, 2017Assignee: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Changsheng Liu, Wanli Xing, Jing Wang, Jiangchao Qian, Jing Liang
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Publication number: 20150337025Abstract: Disclosed is the use of a fusion protein in drugs for stimulating differentiation of bone marrow mesenchymal stem cells to hematopoietic stem/progenitor cells, or drugs for proliferation of granulocyte hematopoietic progenitor cells. The fusion protein has a sequence as shown in SEQ ID NO: 2 or SEQ ID NO: 4. The drugs can be used for the prevention and/or treatment of (i) hematopoietic dysfunction caused by chemotherapy, (ii) hematopoietic dysfunction caused by radiotherapy, or (iii) leukopenia.Type: ApplicationFiled: December 5, 2013Publication date: November 26, 2015Inventors: Changsheng LIU, Wanli XING, Jing WANG, Jiangchao QIAN, Jing LIANG
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Publication number: 20150289534Abstract: A method for preparing functional edible oil rich in phytosterol esters and diglycerides includes steps of: 1) adding phytosterol, triglyceride and a molecular sieve into a reactor, wherein a ratio of the phytosterol and the triglyceride is 1:2-1:6, a molecular sieve amount is 50 g/L; heating to 45-60° C., stirring and ultrasonically treating for 30-60 min; 2) adding 5-20g/L lipase, 100-200 ppm antioxidant, stirring and reacting for 8-12 h with a temperature of 45-60° C. and an atmospheric pressure, stopping heating and naturally cooling to a room temperature; and 3) after reaction, removing the lipase and the molecular sieve by centrifugation, for obtaining the functional edible oil rich in the phytosterol esters and the diglycerides. Products of the present invention do not need separation and purification, and operation is simple.Type: ApplicationFiled: April 4, 2014Publication date: October 15, 2015Inventors: Fenghong Huang, Mingming Zheng, Qing Huang, Pingmei Guo, Jie Shi, Qianchun Deng, Chuyun Wan, Wenlin Li, Mei Yang, Yanxing Niu, Qingde Huang, Changsheng Liu, Jiqu Xu
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Publication number: 20150271416Abstract: The present application describes an information processing method for solving a technical problem of low efficiency in an electronic device. The method includes capturing the first image by a first image capturing unit among at least two image capturing units, and at the same time, capturing a second image by a second image capturing unit among the at least two image capturing units, where the first image and the second image correspond to the same captured object; such that the pixels in the first image is less than those in the second image; transmitting the first image and the second image to an image processing unit; in the process of transmitting the second image, determining a processing way according to at least one characteristic parameter information corresponding to the first image by the image processing unit.Type: ApplicationFiled: September 29, 2014Publication date: September 24, 2015Applicant: LENOVO (BEIJING) CO., LTD.Inventors: Wenbin Song, Changsheng Liu, Yuru Jin
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Patent number: 8703208Abstract: The invention disclosed a novel mesoporous silica-based xerogel and its use in hemorrhage control. The mesoporous silica-based xerogel material has tunable mesopores (1-50 nm), high specific surface area (100-1400 m2/g), macroscopical morphology (powder, film, disc, column, etc.) and adjustable compositions (SiO2, CaO and P2O5, etc.) as well as good biodegradation. The mesoporous silica-based xerogels herein effectively promote the blood clotting under various conditions including slow and severe hemorrhage, even at the blood oozing site of bone defect. Meanwhile, the networks of silica-based xerogel with good elastic and mechanic properties, formed by adsorbing a large amount of water, can modulate the cell behavior and tissue growth, and thus promote the wound healing. Additionally, due to the mesoporous structure, the materials have the potential to load drug, thrombin and bioactive factors, which is favorable for the therapeutical efficacy.Type: GrantFiled: March 13, 2009Date of Patent: April 22, 2014Assignee: East China University of Science and TechnologyInventors: Changsheng Liu, Yuan Yuan
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Patent number: 8086410Abstract: A method for detecting DNA variation. First, by aligning trace data of a sample DNA sequence to trace data of a reference DNA sequence to produce an aligned sample DNA sequence. Then, inputting the trace data of the bases of both the reference DNA sequence and the aligned sample DNA sequence for a particular frame number into a non-linear mathematical function of an anti-correlation calculation scheme for all the frame numbers. Minimal values will be produced at the particular frame number for DNA base trace data of the aligned sample DNA sequence which are not a variation as compared to the reference DNA sequence. Values above the minimal values will be produced at the particular frame number for DNA base trace data of the aligned sample DNA sequence which are a variation as compared to the reference DNA sequence.Type: GrantFiled: May 9, 2008Date of Patent: December 27, 2011Inventors: Changsheng Liu, Fei Gao
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Publication number: 20110232356Abstract: An electrophoretic system having a plurality of separation lanes is provided with an automatic calibration feature in which each lane is separately calibrated. For each lane, the calibration coefficients map a spectrum of received channel intensities onto values reflective of the relative likelihood of each of a plurality of dyes being present. Individual peaks, reflective of the influence of a single dye, are isolated from among the various sets of detected light intensity spectra, and these can be used to both detect the number of dye components present, and also to establish exemplary vectors for the calibration coefficients which may then be clustered and further processed to arrive at a calibration matrix for the system. The system thus permits one to use different dye sets to tag DNA nucleotides in samples which migrate in separate lanes, and also allows for in-situ calibration with new, previously unused dye sets.Type: ApplicationFiled: March 21, 2011Publication date: September 29, 2011Applicant: Life Technologies CorporationInventors: Changsheng LIU, Hequan Zhao
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Publication number: 20110220508Abstract: An automated capillary zone electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends projecting from one side of a plate. The first array of capillary ends is spaced apart in substantially the same manner as the wells of a microtitre tray of standard size. This allows one to simultaneously perform capillary electrophoresis on samples present in each of the wells of the tray. The system includes a stacked, dual carrousel arrangement to eliminate cross-contamination resulting from reuse of the same buffer tray on consecutive executions from electrophoresis. The system also has a container connected to the detection end of the capillaries. The container is provided with valving which facilitate cleaning the capillaries, loading buffer into the capillaries, introducing samples to be electrophoresced into the capillaries, and performing capillary zone electrophoresis on the thus introduced samples.Type: ApplicationFiled: March 15, 2011Publication date: September 15, 2011Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Changsheng LIU, Thomas E. KANE, Qingbo LI