Abstract: An assembly for aligning and supporting an adapter flange for connecting fluid pressures to a pressure sensor body in place on the body and to keep the flange in an unsealed condition to prevent pressurizing the body and flange until installation of permanent fasteners. The support fasteners keep the flange oriented in its normal usable position, but the fasteners retain the flange spaced from the body sufficiently so that the flange will not seal. This will prevent accidentally pressurizing the flange and pressure sensor body until permanent fasteners have been installed. The pressure sensor body is provided with threaded openings for receiving permanent fasteners and the body and flange are shipped with at least one extra set of permanent fasteners different in length from the fasteners used on the flange to permit adding adapters for a process correction.

Abstract: Methods for recovering t-PA from a liquid medium are disclosed. The methods comprise contacting a liquid medium with at least one substrate capable of effecting a separation of intact t-PA from degraded t-PA thereafter recovering the intact t-PA free from other unrelated protein. The present invention also provides compounds produced by this method, compounds comprising intact one-chain t-PA and pharmaceutical compositions containing them and methods for using such compositions.

Abstract: A quick-dissolving antihemophilic factor preparation is obtained by adjusting the pH of buffer-extracted plasma cryoprecipitate to from about pH 6 to about pH 7.0 and cooling to a temperature of from about 2.degree.C to about 20.degree.C for from about 15 minutes to about 1 hour, in order to precipitate certain protein impurities, primarily fibrinogen.