Abstract: An instrument includes a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to close off a fluidic channel in the body. A cartridge interface is configured to engage the cartridge.

Abstract: Systems and methods are provided for merging task graphs representing variants of an automatable task into a merged task graph. A plurality of task graphs each representing a variant of an automatable task is received. Similarities between the plurality of task graphs are identified. The plurality of task graphs is merged into a merged task graph of the automatable task based on the identified similarities. The merged task graph is output.

Abstract: Systems and methods are provided for determining variants of an automatable task. Task flow data of a performance of an automatable task by one or more users is received. The task flow data is generated based on user input using task mining. User interaction data is identified from the task flow data. One or more variants of the automatable task are determined based on the user interaction data using a machine learning based model. The one or more variants of the automatable task are output.

Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4. The anti-B7-H4 antibodies or antigen-binding fragments thereof are useful, for example in detecting B7-H4. Immunohistochemistry (IHC) can be used to detect B7-H4. The present disclosure also provides methods for treating cancer wherein increased B7-H4 has been detected, by administering a therapeutic anti-B7-H4 antibody or antigen-binding fragment thereof.

Abstract: The present disclosure provides a light detection and ranging (LIDAR) system, which comprises: a distance measuring unit configured to emit a plurality of first pulses towards an object located in a field of view (FOV), wherein the object is associated with one or more markers; and a detector configured to receive at least one second pulse from the one or more markers of the object, wherein each of the at least one second pulse indicates object information identifying the object.

Abstract: Disclosed herein is a method implemented by a task mining engine. The task mining engine is stored as processor executable code on a memory. The processor executable code is executed by a processor that is communicatively coupled to the memory. The method includes receiving recorded tasks identifying user activity with respect to a computing environment and clustering the recorded user tasks into steps by processing and scoring each recorded user task. The method also includes extracting step sequences that identify similar combinations or repeated combinations of the steps to mimic the user activity.

Abstract: A method for visualizing a process map is executed by a process map server. The method includes receiving a flowchart and a step-by-step recording related to a process. Generating a process map by combining the flowchart and the step-by-step recording and displaying the process map. The process map displays a task, step, and action related to the process. A detail window shows information associated with the process, and portions of the process, in response to user input. The action is based on information from the step-by-step recording.

Abstract: Components for valve treatment systems are disclosed. Valve treatment systems can include a delivery system for an implantable device. The delivery system can include one or more of clasp control components slidably disposed on a catheter handle, a control element for opening and closing the implantable device, a catheter assembly with features to reduce friction with another catheter assembly, grips for attaching catheter assemblies to clamps, catheter assemblies with features that stiffen or provide variable stiffness, and catheter assemblies with one or more steering control lumens incorporated into a reinforcement layer.

Abstract: Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

Abstract: System and method embodiments for placement of Centralized Discovery Controller (CDC) services on a switching network fabric are disclosed. Nodes on the switching network fabric are categorized into leader nodes, e.g., spine switches, and follower nodes, e.g., leaf switches. The CDC services are divided into centralized CDC services and distributed CDC services, which has direct connections to endpoints for seamless horizontal scaling of endpoints. The centralized CDC services are placed on a leader node and the distributed CDC services are placed among the follower nodes. Operations of the CDC services are monitored. In case of a node failure, CDC services deployed on the failed node are moved or transferred to one or more other nodes that have the same role as the failed node. Implementation of the CDC service placement embodiments enables seamless horizontal scaling for endpoints and provides capability for more visibility and monitoring of endpoint.

Abstract: In a network fabric, such as a network having CLOS topology, non-volatile memory express (NVMe®) endpoints may be connected to one of centralized discovery controller (CDC) distributed services placed among multiple leaf switches, which may have resource constraints. Connection scale, delay, and jitter may occur if the CDC distributed services are not placed on leaf switches close to NVMe endpoints served by the CDC distributed services. System and method embodiments are disclosed for placement of CDC services on a switching network fabric close to endpoints that are served by the CDC services. The placement of CDC services may be implemented via push registration, pull registration, and/or manual DDC adding/registration such that the CDC services may be placed on desired leaf switches close to endpoints.

Abstract: A method for visualizing a process map is executed by a process map server. The method includes receiving a flowchart and a step-by-step recording related to a process. Generating a process map by combining the flowchart and the step-by-step recording and displaying the process map. The process map displays a task, step, and action related to the process. A detail window shows information associated with the process, and portions of the process, in response to user input. The action is based on information from the step-by-step recording.

Abstract: A live help provider graphical user interface depicting a provider graphical representation of a client device located at a user location and respective provider graphical representations of additional devices located at the user location in a manner that identifies each of the additional devices and depicts a spatial relationship of each of the additional devices relative to the client device at the user location.

Abstract: A method of controlling fluid flow in a fluid channel of fluidic cartridge can include closing a valve by actuating a mechanical actuator against the valve to force a deformable layer against walls of a valve body, wherein the valve body comprises a valve inlet and a valve outlet and each of the valve inlet and valve outlet are fluidically coupled to a fluidic channel; releasing the valve by retracting the mechanical actuator away from the valve body; and moving liquid through the valve by applying positive or negative pressure to the fluidic channel.

Abstract: A live help system provides an intuitive display of help information on a user's graphical user interface. A request is received from a client device for help, and a live help provider interface is initiated at a live help location. Data is acquired regarding a user's location, including data on external devices in the user's location. Indicators are provided to allow the live help provider to point to or otherwise indicate items on the user interface or outside of the user interface. Live help input is captured at the live help provider interface. Instructions are then transmitted to the display of the client device to display live help input, as though the agent were present and interacting with or indicating items on the screen or off the screen.

Abstract: A method of making an article bonding a layer of deformable material to a surface of a cartridge body having at least one valve body thereon to seal the at least one valve body, the valve body comprising a valve floor and valve walls comprising upper parts, wherein the valve floor is recessed from the surface and the valve walls extend from the surface to the valve floor, and wherein the valve body comprises walls that are curved or sloped in a direction that is non-normal to the plane defined by the surface; and deforming the layer such that upon release of a force causing the deformation, the layer is in contact with the upper parts of the valve walls and is in spaced from the valve floor so as to bias the valve to an open state.

Abstract: A system comprises an authentication sub-system configured to authenticate a user and a biochemical analysis sub-system configured to perform a biochemical analysis on a biological sample provided to the biochemical analysis sub-system. The system is configured to authenticate a user using the authentication sub-system, instruct an authenticated user to provide a biological sample to the biochemical analysis sub-system, execute a biochemical analysis on a provided biological sample.

Abstract: A biometric biochemical analysis system includes a user interface module to provide instructions for collecting and handling biochemical sampling and processing related to biometric data gathering as well as capturing biometric data using digital data capturing devices. The user interface module and display are integrated with analysis and communications portions of the biometric biochemical analysis system to provide a portable system for multi-portion data collecting, storage, verification, and analysis.

Abstract: A data storage device is disclosed comprising a head actuated over a magnetic media comprising a plurality of tracks. A first pattern of magnetic transitions is written to a first segment of a first track. Preparation is made to write a second pattern of magnetic transitions to a second segment of a second track adjacent the first segment of the first track. When the second pattern matches the first pattern, a write boost is configured to a first setting, and when the second pattern does not match the first pattern, the write boost is configured to a second setting. The second pattern of magnetic transitions is then written to the second segment of the second track using the configured write boost.

Abstract: Disclosed herein is a method implemented by a task mining engine. The task mining engine is stored as processor executable code on a memory. The processor executable code is executed by a processor that is communicatively coupled to the memory. The method includes receiving recorded tasks identifying user activity with respect to a computing environment and clustering the recorded user tasks into steps by processing and scoring each recorded user task. The method also includes extracting step sequences that identify similar combinations or repeated combinations of the steps to mimic the user activity.