Patents by Inventor Charles Auxilium Francis

Charles Auxilium Francis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for manufacturing opioid analgesics
    Patent number: 7071336
    Abstract: Oxycodone is manufactured in high yields and with a high purity using a composition including a thebaine component into 14-hydroxycodeinone and then reduction of 14-hydroxycodeinone to oxycodone.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: July 4, 2006
    Assignee: Acura Pharmaceuticals
    Inventors: Charles Auxilium Francis, Zhaiwei Lin, Christopher Arne Kaldahl, Kazimierz Grzegorz Antczak, Vijai Kumar
  • Contact lens with PVA cover layer
    Patent number: 6890075
    Abstract: A contact lens having a cover layer of polyvinyl alcohol and an opaque simulated iris pattern and an associated method of manufacture. The opaque simulated iris pattern obscures the underlying natural iris for superior color transformation, and provides enhanced cosmetic effect.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: May 10, 2005
    Assignee: Novartis AG
    Inventors: Charles Auxilium Francis, Richard Charles Turek, Donald E. Keeley
  • Process for manufacturing oxycodone
    Patent number: 6864370
    Abstract: Oxycodone is manufactured in high yields and with a high purity using codeine or a salt of codeine as the starting material. The manufacturing process involves the following steps: (a) codeine or a codeine salt (e.g.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: March 8, 2005
    Inventors: Zhaiwei Lin, Charles Auxilium Francis, Christopher Arne Kaldahl, Kazimierz Grzegorz Antczak, Vijai Kumar
  • Process for manufacturing thebaine
    Patent number: 6790959
    Abstract: Thebaine is manufactured in high yields and with a high purity using codeine or a salt of codeine as the starting material. The manufacturing process involves the following steps: (a) codeine or a codeine salt (e.g., codeine phosphate) is converted into the intermediate N-carboalkoxy- or N-carboaryloxynorcodeine; (b) the intermediate N-carboalkoxy- or N-carboaryloxynorcodeine resulting from step (a) is oxidized to yield the intermediate N-carboalkoxy- or N-carboaryloxynorcodeine; (c) the intermediate N-carboalkoxy- or N-carboaryloxynorcodeinone resulting from step (b) is enolized with a base and the resultant enolate is thereafter methylated to yield the intermediate N-carboalkoxy- or N-carboaryloxynorthebaine; and (d) the intermediate N-carboalkoxy- or N-carboaryloxynorthebaine resulting from step (c) is reduced to yield thebaine.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: September 14, 2004
    Assignee: Halsey Drug Company, Inc.
    Inventors: Zhaiwei Lin, Charles Auxilium Francis, Christopher Arne Kaldahl, Kazimierz Grzegorz Antczak, Vijai Kumar
  • Contact lens with PVA cover layer
    Publication number: 20030035083
    Abstract: A contact lens having a cover layer of polyvinyl alcohol and an opaque simulated iris pattern and an associated method of manufacture. The opaque simulated iris pattern obscures the underlying natural iris for superior color transformation, and provides enhanced cosmetic effect.
    Type: Application
    Filed: May 22, 2002
    Publication date: February 20, 2003
    Inventors: Charles Auxilium Francis, Richard Charles Turek, Donald E. Keeley
  • Contact lens with opaque iris pattern
    Publication number: 20020167640
    Abstract: A contact lens having an opaque simulated iris pattern and an associated method of manufacture. The opaque simulated iris pattern obscures the underlying natural iris for superior color transformation, and provides enhanced cosmetic effect.
    Type: Application
    Filed: December 14, 2001
    Publication date: November 14, 2002
    Inventors: Charles Auxilium Francis, Richard Charles Turek