Patents by Inventor Charles Bormann

Charles Bormann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240078675
    Abstract: Systems and methods are provided for provided for automatic evaluation of a human embryo. An image of the embryo is obtained and provided to a neural network to generate a plurality of values representing the morphology of the embryo. The plurality of values representing the morphology of the embryo are evaluated at an expert system to provide an output class representing one of a current quality of the embryo, a future quality of the embryo, a likelihood that implantation of the embryo will be successful, and a likelihood that implantation of the embryo will result in a live birth.
    Type: Application
    Filed: November 13, 2023
    Publication date: March 7, 2024
    Inventors: Hadi Shafiee, Charles Bormann, Manoj Kumar Kanakasabapathy, Prudhvi Thirumalaraju
  • Patent number: 11816753
    Abstract: Systems and methods are provided for provided for automatic evaluation of a human embryo. An image of the embryo is obtained and provided to a neural network to generate a plurality of values representing the morphology of the embryo. The plurality of values representing the morphology of the embryo are evaluated at an expert system to provide an output class representing one of a current quality of the embryo, a future quality of the embryo, a likelihood that implantation of the embryo will be successful, and a likelihood that implantation of the embryo will result in a live birth.
    Type: Grant
    Filed: April 12, 2022
    Date of Patent: November 14, 2023
    Assignees: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., THE GENERAL HOSPITAL CORPORATION
    Inventors: Hadi Shafiee, Charles Bormann, Manoj Kumar Kanakasabapathy, Prudhvi Thirumalaraju
  • Publication number: 20230326165
    Abstract: Systems and methods are provided for determining a clinical parameter representing the location of interest within a reproductive cellular structure. An image of the reproductive cellular structure is obtained and provided to a neural network to generate the clinical parameter. The clinical parameter is stored on a non-transitory computer readable medium.
    Type: Application
    Filed: September 13, 2021
    Publication date: October 12, 2023
    Inventors: Hadi Shafiee, Charles Bormann, Manoj Kumar Kanakasabapathy, Prudhvi Thirumalaraju
  • Publication number: 20230326014
    Abstract: Systems and methods are provided for fully automated screening for aneuploidy in a human embryo. An image of the embryo is obtained at an associated imager and provided to a neural network to generate a first clinical parameter. A set of at least one parameter representing one of biometric parameters of one of a patient receiving the embryo, an egg utilized to produce the human embryo, a sperm used to create the embryo, a sperm donor who provided sperm used to create the embryo, and an egg donor who provided the egg is retrieved, and a second clinical parameter is generated from the set of at least one parameter at a predictive model. A composite parameter, representing a likelihood of aneuploidy in the embryo, is generated from the first clinical parameter and the second clinical parameter.
    Type: Application
    Filed: September 13, 2021
    Publication date: October 12, 2023
    Inventors: Hadi Shafiee, Charles Bormann, Manoj Kumar Kanakasabapathy, Prudhvi Thirumalaraju
  • Publication number: 20220237791
    Abstract: Systems and methods are provided for provided for automatic evaluation of a human embryo. An image of the embryo is obtained and provided to a neural network to generate a plurality of values representing the morphology of the embryo. The plurality of values representing the morphology of the embryo are evaluated at an expert system to provide an output class representing one of a current quality of the embryo, a future quality of the embryo, a likelihood that implantation of the embryo will be successful, and a likelihood that implantation of the embryo will result in a live birth.
    Type: Application
    Filed: April 12, 2022
    Publication date: July 28, 2022
    Inventors: Hadi Shafiee, Charles Bormann, Manoj Kumar Kanakasabapathy, Prudhvi Thirumalaraju
  • Patent number: 11321831
    Abstract: Systems and methods are provided for provided for automatic evaluation of a human embryo. An image of the embryo is obtained and provided to a neural network to generate a plurality of values representing the morphology of the embryo. The plurality of values representing the morphology of the embryo are evaluated at an expert system to provide an output class representing one of a current quality of the embryo, a future quality of the embryo, a likelihood that implantation of the embryo will be successful, and a likelihood that implantation of the embryo will result in a live birth.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: May 3, 2022
    Assignees: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., THE GENERAL HOSPITAL CORPORATION
    Inventors: Hadi Shafiee, Charles Bormann, Manoj Kumar Kanakasabapathy, Prudhvi Thirumalaraju
  • Publication number: 20200226750
    Abstract: Systems and methods are provided for provided for automatic evaluation of a human embryo. An image of the embryo is obtained and provided to a neural network to generate a plurality of values representing the morphology of the embryo. The plurality of values representing the morphology of the embryo are evaluated at an expert system to provide an output class representing one of a current quality of the embryo, a future quality of the embryo, a likelihood that implantation of the embryo will be successful, and a likelihood that implantation of the embryo will result in a live birth.
    Type: Application
    Filed: October 1, 2018
    Publication date: July 16, 2020
    Inventors: Hadi Shafiee, Charles Bormann, Manoj Kumar Kanakasabapathy, Prudhvi Thirumalaraju
  • Publication number: 20130034906
    Abstract: The invention relates to methods for assisted reproduction technology in mammals. Specifically the invention relates to methods for in vitro mammalian oocyte culture and oocyte maturation, in vitro fertilization, and in vitro embryo development.
    Type: Application
    Filed: January 7, 2011
    Publication date: February 7, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Gary D. Smith, Shuichi Takayama, Charles Bormann, Yunseok Heo