Patents by Inventor Charles Carson Bascom
Charles Carson Bascom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220409512Abstract: An oral care composition with gum health compound, amino acid, and/or mucoadhesive compound. An oral care composition with gum health compound, a pentapeptide, such as palmitoyl KTTKS, and/or a mucoadhesive compound. Methods of preventing gingival recession, stopping gingival recession, reversing gingival recession, decrease gum recession, increase gingival barrier protection, promoting collagen synthesis, promoting extracellular matrix synthesis, increasing gum resilience, increasing epidermal thickness and/or promoting fibrillin synthesis, in an oral cavity of an animal by contacting the oral care compositions with at least one surface of the oral cavity.Type: ApplicationFiled: August 22, 2022Publication date: December 29, 2022Inventors: Charles Carson BASCOM, Aaron Reed BIESBROCK, Robert Joseph ISFORT, Malgorzata Anne KLUKOWSKA, Yunming SHI, Ross STRAND, Ryan TASSEFF
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Publication number: 20220401343Abstract: An oral care composition with gum health compound, amino acid, and/or mucoadhesive compound. An oral care composition with gum health compound, a pentapeptide, such as palmitoyl KTTKS, and/or a mucoadhesive compound. Methods of preventing gingival recession, stopping gingival recession, reversing gingival recession, decrease gum recession, increase gingival barrier protection, promoting collagen synthesis, promoting extracellular matrix synthesis, increasing gum resilience, increasing epidermal thickness and/or promoting fibrillin synthesis, in an oral cavity of an animal by contacting the oral care compositions with at least one surface of the oral cavity.Type: ApplicationFiled: August 22, 2022Publication date: December 22, 2022Inventors: Charles Carson BASCOM, Aaron Reed BIESBROCK, Robert Joseph ISFORT, Malgorzata Anne KLUKOWSKA, Yunming SHI, Ross STRAND, Ryan TASSEFF
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Patent number: 10732171Abstract: Human skin tissue sample methods and models for identifying and screening test agents as effective for providing skin tone benefits, methods for validating hypotheses for mechanisms driving skin pigmentation as well as methods for driving skin pigment levels in ex-vivo skin tissue. The method includes contacting a cultured human skin tissue sample with a test agent, generating a transcriptional profile from the sample, and comparing the results to a control to determine if the test agent is effective for providing a skin tone benefit.Type: GrantFiled: December 20, 2012Date of Patent: August 4, 2020Assignee: The Procter & Gamble CompanyInventors: Deborah Ruth Finlay, Tomohiro Hakozaki, Charles Carson Bascom, Heather Eileen Matheny
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Patent number: 10036741Abstract: Methods and systems for constructing a gene expression signature representative of a number of biological conditions, systems and methods for determining functional relationships between a skin-active agent and skin conditions of interest, and methods and systems for identifying skin-active agents with broad spectrum activity are provided.Type: GrantFiled: August 14, 2013Date of Patent: July 31, 2018Assignee: The Procter & Gamble CompanyInventors: Kevin John Mills, Jun Xu, Robert Lloyd Binder, Robert Scott Youngquist, Deborah Ruth Finlay, Charles Carson Bascom
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Publication number: 20170340251Abstract: An array of methods for assessing vaginal atrophy are disclosed. The methods may be used alone or in combination with a treatment or as part of a kit.Type: ApplicationFiled: June 15, 2017Publication date: November 30, 2017Inventors: Raphael Warren, Dean Larry DuVal, Miranda Aref Farage, Charles Carson Bascom, Gina Marie Fadayel, Kenneth Robert Wehmeyer, Jay Patrick Tiesman, David Burton Moore, Murray A. Freedman
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Publication number: 20170343534Abstract: Methods and systems for constructing a gene expression signature representative of a number of biological conditions, systems and methods for determining functional relationships between a skin-active agent and skin conditions of interest, and methods and systems for identifying skin-active agents with broad spectrum activity are provided.Type: ApplicationFiled: August 14, 2013Publication date: November 30, 2017Applicant: The Procter & Gamble CompanyInventors: Kevin John MILLS, Jun XU, Robert Lloyd BINDER, Robert Scott YOUNGQUIST, Deborah Ruth FINLAY, Charles Carson BASCOM
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Patent number: 9804152Abstract: Provided are methods and systems for determining functional relationships between ex vivo skin models and an inflammatory skin condition. Also provided are methods and systems for identifying modulators of inflammation of skin, as well as the use of modulators identified by such methods or systems for the preparation of cosmetic compositions, personal care products, or both.Type: GrantFiled: August 15, 2013Date of Patent: October 31, 2017Assignee: The Procter & Gamble CompanyInventors: Deborah Ruth Finlay, Kevin John Mills, Charles Carson Bascom
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Patent number: 9706951Abstract: An array of methods for assessing vaginal atrophy are disclosed. The methods may be used alone or in combination with a treatment or as part of a kit.Type: GrantFiled: January 25, 2016Date of Patent: July 18, 2017Assignee: The Procter & Gamble CompanyInventors: Raphael Warren, Dean Larry DuVal, Miranda Aref Farage, Charles Carson Bascom, Gina Marie Fadayel, Kenneth Robert Wehmeyer, Jay Patrick Tiesman, David Burton Moore, Murray A. Friedman
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Publication number: 20170181697Abstract: A kit for assessing efficacy of a vaginal atrophy treatment regimen is disclosed. The kit includes a pretreatment assessment method for vaginal atrophy comprising and a topical treatment for application to the labia majora, labia minora, introitus, vagina, or combinations thereof.Type: ApplicationFiled: March 10, 2017Publication date: June 29, 2017Inventors: Raphael Warren, Dean Larry DuVal, Miranda Aref Farage, Charles Carson Bascom, Gina Marie Fadayel, Kenneth Robert Wehmeyer, Jay Patrick Tiesman, David Burton Moore, Murray A. Friedman
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Patent number: 9593363Abstract: A screening method for identifying an agent as effective for providing an anti-aging skin benefit is provided. The screening method includes culturing first and second human skin samples from about 3 days to about 19 days, wherein the first and second human skin samples are derived from a human skin surgical waste tissue. The first human skin sample is contacted with at least one test agent. The second human skin sample is contacted with a positive control. Transcriptional profiles are generated from the first and second human skin samples, and the at least one test agent is identified as effective for providing an anti-aging skin benefit when the transcriptional profiles of at least two genes show a similar directional change in comparison to one or more untreated control tissue samples.Type: GrantFiled: June 17, 2013Date of Patent: March 14, 2017Assignee: The Procter & Gamble CompanyInventors: Deborah Ruth Finlay, Rosemarie Osborne, Charles Carson Bascom
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Publication number: 20160135722Abstract: An array of methods for assessing vaginal atrophy are disclosed. The methods may be used alone or in combination with a treatment or as part of a kit.Type: ApplicationFiled: January 25, 2016Publication date: May 19, 2016Inventors: Raphael Warren, Dean Larry DuVal, Miranda Aref Farage, Charles Carson Bascom, Gina Marie Fadayel, Kenneth Robert Wehmeyer, Jay Patrick Tiesman, David Burton Moore, Murray A. Friedman
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Publication number: 20160007906Abstract: An array of methods for assessing vaginal atrophy are disclosed. The methods may be used alone or in combination with a treatment or as part of a kit.Type: ApplicationFiled: July 10, 2015Publication date: January 14, 2016Inventors: Raphael Warren, Dean Larry DuVal, Miranda Aref Farage, Charles Carson Bascom, Gina Marie Fadayel, Kenneth Robert Wehmeyer, Jay Patrick Tiesman, David Burton Moore, Murray A. Freedman
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Publication number: 20150004616Abstract: Human skin tissue sample methods and models for identifying and screening test agents as effective for providing skin tone benefits, methods for validating hypotheses for mechanisms driving skin pigmentation as well as methods for driving skin pigment levels in ex-vivo skin tissue. The method includes contacting a cultured human skin tissue sample with a test agent, generating a transcriptional profile from the sample, and comparing the results to a control to determine if the test agent is effective for providing a skin tone benefit.Type: ApplicationFiled: December 20, 2012Publication date: January 1, 2015Inventors: Deborah Ruth Finlay, Tomohiro Hakozaki, Charles Carson Bascom, Heather Eileen Matheny
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Publication number: 20140335532Abstract: Human skin tissue sample methods and models for validating hypotheses for mechanisms driving skin pigmentation as well as methods for driving skin pigment levels in ex-vivo skin tissue. The method includes providing a first cultured human skin tissue sample and testing the effectiveness of the test agent for driving skin pigmentation, and comparing the transcriptional profile generated from the treated human skin tissue sample to the transcriptional profile of a control to validate the hypothesis that the test agent drives skin pigmentation.Type: ApplicationFiled: December 20, 2012Publication date: November 13, 2014Inventors: Deborah Ruth Finlay, Tomohiro NMN Hakozaki, Charles Carson Bascom, Heather Eileen Matheny
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Publication number: 20130337087Abstract: A screening method for identifying an agent as effective for providing an anti-aging skin benefit is provided. The screening method includes culturing first and second human skin samples from about 3 days to about 19 days, wherein the first and second human skin samples are derived from a human skin surgical waste tissue. The first human skin sample is contacted with at least one test agent. The second human skin sample is contacted with a positive control. Transcriptional profiles are generated from the first and second human skin samples, and the at least one test agent is identified as effective for providing an anti-aging skin benefit when the transcriptional profiles of at least two genes show a similar directional change in comparison to one or more untreated control tissue samples.Type: ApplicationFiled: June 17, 2013Publication date: December 19, 2013Inventors: Deborah Ruth FINLAY, Rosemarie OSBORNE, Charles Carson BASCOM
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Patent number: 8591874Abstract: The present invention relates to a topical skin care composition containing a safe and effective amount of a skin care active comprising agmatine, and its salt; a safe and effective amount of a first additional skin care active selected from the group consisting of BHT or BHA, hexamidine, cetyl pyridinium chloride, green tea catechins, phytosterols, ursolic acid, compounds derived from plant extracts, their salts and derivatives; and a dermatologically acceptable carrier for the agmatine composition. The present invention also relates to methods of using such agmatine compositions to regulate hair growth and the condition of mammalian skin. The methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.Type: GrantFiled: February 1, 2006Date of Patent: November 26, 2013Assignee: The Procter & Gamble CompanyInventors: John Erich Oblong, Sara Johnson McPhail, Shannon Christine McArthur, Charles Carson Bascom, David Joseph Eickhoff, John McMillan McIver
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Patent number: 8481015Abstract: The present invention relates to a topical skin care composition containing a safe and effective amount of a skin care active comprising agmatine, and its salt; a safe and effective amount of a first additional skin care active selected from the group consisting of BHT or BHA, hexamidine, cetyl pyridinium chloride, green tea catechins, phytosterols, ursolic acid, compounds derived from plant extracts, their salts and derivatives; and a dermatologically acceptable carrier for the agmatine composition. The present invention also relates to methods of using such agmatine compositions to regulate hair growth and the condition of mammalian skin. Said methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.Type: GrantFiled: March 27, 2008Date of Patent: July 9, 2013Assignee: The Procter & Gamble CompanyInventors: John Erich Oblong, Sara Johnson McPhail, Shannon Christine McArthur, Charles Carson Bascom, David Joseph Eickhoff, John McMillan McIver
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Publication number: 20080188505Abstract: The present invention relates to a topical skin care composition containing a safe and effective amount of a skin care active comprising agmatine, and its salt; a safe and effective amount of a first additional skin care active selected from the group consisting of BHT or BHA, hexamidine, cetyl pyridinium chloride, green tea catechins, phytosterols, ursolic acid, compounds derived from plant extracts, their salts and derivatives; and a dermatologically acceptable carrier for the agmatine composition. The present invention also relates to methods of using such agmatine compositions to regulate hair growth and the condition of mammalian skin. Said methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.Type: ApplicationFiled: March 27, 2008Publication date: August 7, 2008Inventors: John Erich Oblong, Sara Johnson McPhail, Shannon Christine McArthur, Charles Carson Bascom, David Joseph Eickhoff, John McMillan McIver
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Publication number: 20030069618Abstract: The present invention concerns a method and a kit, for the treatment of a selected area of the skin and/or subcutaneous tissue, and in particular for the cosmetic treatment of skin conditions such as regional fat deposits including cellulite. The method comprises heating the selected area to a sustained skin temperature of about 32 to about 50° C. for a desired period of time, using a device comprising either a heat source capable of conductively heating the selected area or, alternatively, an infra-red source for emitting infra-red with a wavelength from about 700 nm to about 15000 nm.Type: ApplicationFiled: April 25, 2002Publication date: April 10, 2003Inventors: Edward Dewey Smith, John Erich Oblong, Jonathan Todd Samuel, Donald Lynn Bissett, Charles Carson Bascom, Gary Robert Kelm