Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.

Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.

Abstract: A method of identifying a structure in a volume of data. The method includes steps of generating a scalar mask volume which corresponds to at least a portion of the volume of data; displaying the volume of data to a user through a viewport; obtaining from a user at least one seed region identified on the viewport; projecting the seed region from the viewport into the scalar mask volume to identify at least one segmentation seed within the scalar mask volume; obtaining from a user at least one diffusion region identified on the viewport; projecting the diffusion region from the viewport into the scalar mask volume to identify a region for seed growth within the scalar mask volume; and growing the at least one segmentation seed within the scalar mask volume to identify a structure within the volume of data.

Abstract: Step-shaped innerframes and blanks for forming such innerframes are provided to permit shorter than conventional cigarettes to be packaged in a conventionally sized hinged lid box. A front panel is foldably connected to a substantially perpendicular step bottom panel which in turn is foldably connected to a substantially perpendicular back panel, such that the front and back panels extend in opposite directions and lie in substantially parallel planes to form an integral step configuration. When the inner frame is located within a hinged lid box, a receptacle is formed for a short cigarette bundle. A lower receptacle is defined below the step bottom panel to store discarded cigarettes which are inserted into the lower receptacle via a hole located in one of the box walls and any associated underlying innerframe panel.

Abstract: Step-shaped innerframes and blanks for forming such innerframes are provided to permit shorter than conventional cigarettes to be packaged in a conventionally sized hinged lid box. A front panel is foldably connected to a substantially perpendicular step bottom panel which in turn is foldably connected to a substantially perpendicular back panel, such that the front and back panels extend in opposite directions and lie in substantially parallel planes to form an integral step configuration. When the inner frame is located within a hinged lid box, a receptacle is formed for a short cigarette bundle. A lower receptacle is defined below the step bottom panel to store discarded cigarettes which are inserted into the lower receptacle via a hole located in one of the box walls and any associated underlying innerframe panel.

Abstract: A cigarette package comprises a plurality of packs, and a binder member bonded to adjoining edge faces of the packs. A releasable retainer normally holds the packs together. Upon release of the retainer, the packs can be fanned-out about axes coinciding with adjoining corners of the packs. Any number of the packs can be detached by the user for individual use.

Abstract: In a thresher, means for independently mounting cutters and for replacing each cutter without disturbing other cutters, the rotor or the fixed cutter mounting means.

Abstract: The method and apparatus therefor for separating paper particles from reclaimed shredded tobacco comprising propelling shredded tobacco with paper particles randomly mixed therein into a path of flight above an endless belt coneyor and in the direction of movement of the conveyor so that the shredded tobacco showers down and forms a blanket on the conveyor and the longer flying paper showers down atop the tobacco blanket, the conveyor moving the tobacco past scanning means and propelling the tobacco along a path of flight to receiver means, the scanning means detecting paper particles atop the tobacco, and pneumatic reject means responsive to the scanning means for diverting detected paper particles from the path of flight from the conveyor to a receiver for reject particles.