Patents by Inventor Charles Duke

Charles Duke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF
    Publication number: 20230159421
    Abstract: The present disclosure relates to substituted hydroxystilbene compounds and derivatives, specifically 2-substituted hydroxystilbene compounds and derivatives, the synthesis of such compounds and their use in therapy.
    Type: Application
    Filed: December 23, 2020
    Publication date: May 25, 2023
    Applicant: Kynan Duke IP, LLC
    Inventors: Colin Charles Duke, Rujee Kyokajee DUKE, Van Hoan TRAN
  • Prenylated hydroxystilbenes
    Patent number: 11634375
    Abstract: A compound according to structure USYDS1: wherein the compound is in purified form.
    Type: Grant
    Filed: May 26, 2022
    Date of Patent: April 25, 2023
    Assignee: KYNAN DUKE IP, LLC
    Inventors: Colin Charles Duke, Van Hoan Tran, Rujee Kyokajee Duke
  • PRENYLATED HYDROXYSTILBENES
    Publication number: 20220380285
    Abstract: A compound, composition, or method for treating cancer is disclosed. The compound (that can be used in the composition and/or method) can include or pharmaceutically acceptable salts or solvates thereof. R1a-R1d, R2-R3 (and R4 where applicable), and A---B can be as defined herein.
    Type: Application
    Filed: May 26, 2022
    Publication date: December 1, 2022
    Applicant: Kynan Duke IP, LLC
    Inventors: Colin Charles Duke, Van Hoan TRAN, Rujee Kyokajee DUKE
  • Prenylated hydroxystilbenes
    Patent number: 11352310
    Abstract: A compound, composition, or method for treating cancer is disclosed. The compound (that can be used in the composition and/or method) can include or pharmaceutically acceptable salts or solvates thereof. R1a-R1d, R2-R3 (and R4 where applicable), and A---B can be as defined herein.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: June 7, 2022
    Assignee: KYNAN DUKE IP, LLC
    Inventors: Colin Charles Duke, Van Hoan Tran, Rujee Kyokajee Duke
  • Medicinal use of serrulatane diterpenes
    Patent number: 11331299
    Abstract: The present disclosure is drawn to methods of treating diseases or disorders, and uses of preparing medicaments. The methods of administering and/or preparation of medicaments can include the use of a compound of Formula (I) disclosed herein, or a geometric isomer, stereoisomer, and/or pharmaceutically acceptable salt or solvate thereof.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: May 17, 2022
    Assignee: Kynan Duke IP, LLC
    Inventors: Colin Charles Duke, Rujee Kyokajee Duke, Van Hoan Tran
  • MEDICINAL USE OF SERRULATANE DITERPENES
    Publication number: 20220117930
    Abstract: The present disclosure is drawn to methods of treating diseases or disorders, and uses of preparing medicaments. The methods of administering and/or preparation of medicaments can include the use of a compound of Formula (I) disclosed herein, or a geometric isomer, stereoisomer, and/or pharmaceutically acceptable salt or solvate thereof.
    Type: Application
    Filed: December 16, 2020
    Publication date: April 21, 2022
    Applicant: The University of Sydney
    Inventors: Colin Charles DUKE, Rujee Kyokajee DUKE, Van Hoan TRAN
  • MEDICINAL USE OF SERRULATANE DITERPENES
    Publication number: 20210212982
    Abstract: The present disclosure is drawn to methods of treating diseases or disorders, and uses of preparing medicaments. The methods of administering and/or preparation of medicaments can include the use of a compound of Formula (I) disclosed herein, or a geometric isomer, stereoisomer, and/or pharmaceutically acceptable salt or solvate thereof.
    Type: Application
    Filed: December 16, 2020
    Publication date: July 15, 2021
    Applicant: The University of Sydney
    Inventors: Colin Charles DUKE, Rujee Kyokajee DUKE, Van Hoan TRAN
  • Medicinal use of serrulatane diterpenes
    Patent number: 10912742
    Abstract: The invention relates to terpenes and uses thereof.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: February 9, 2021
    Assignee: The University of Sydney
    Inventors: Colin Charles Duke, Rujee Kyokajee Duke, Van Hoan Tran
  • PRENYLATED HYDROXYSTILBENES
    Publication number: 20200331833
    Abstract: A compound, composition, or method for treating cancer is disclosed. The compound (that can be used in the composition and/or method) can include or pharmaceutically acceptable salts or solvates thereof. R1a-R1d, R2-R3 (and R4 where applicable), and A---B can be as defined herein.
    Type: Application
    Filed: June 30, 2020
    Publication date: October 22, 2020
    Applicant: The University of Sydney
    Inventors: Colin Charles Duke, Van Hoan TRAN, Rujee Kyokajee DUKE
  • Prenylated hydroxystilbenes
    Patent number: 10696615
    Abstract: A method for treating cancer can include administering a therapeutically effective amount of a compound of formula (Ia): or pharmaceutically acceptable salts or solvates thereof, wherein R1a, R1b, R1c, R1d, R2, and R3 are as defined, and A----B is selected from CH?CH, CH?CH(CH2)pCH2, or CH2—CH2(CH2)pCH2, and where p is 1 or 2.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: June 30, 2020
    Assignee: The University of Sydney
    Inventors: Colin Charles Duke, Van Hoan Tran, Rujee Kyokajee Duke
  • MEDICINAL USE OF SERRULATANE DITERPENES
    Publication number: 20190282514
    Abstract: The invention relates to terpenes and uses thereof.
    Type: Application
    Filed: September 7, 2017
    Publication date: September 19, 2019
    Applicant: The University of Sydney
    Inventors: Colin Charles DUKE, Rujee Kyokajee DUKE, Van Hoan TRAN
  • PRENYLATED HYDROXYSTILBENES
    Publication number: 20190194105
    Abstract: A method for treating cancer can include administering a therapeutically effective amount of a compound of formula (Ia): or pharmaceutically acceptable salts or solvates thereof, wherein R1a, R1b, R1c, R1d, R2, and R3 are as defined, and A----B is selected from CH?CH, CH?CH(CH2)pCH2, or CH2—CH2(CH2)pCH2, and where p is 1 or 2.
    Type: Application
    Filed: December 17, 2018
    Publication date: June 27, 2019
    Applicant: The University of Sydney
    Inventors: Colin Charles Duke, Van Hoan Tran, Rujee Kyokajee Duke
  • Prenylated hydroxystilbenes
    Patent number: 10196335
    Abstract: Prenylated stilbene compounds and the use of such compounds in the treatment of diseases and medical disorders, for example cancer, skin ageing, inflammation, bacterial or fungal infection and immunosuppression.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: February 5, 2019
    Assignee: The University of Sydney
    Inventors: Colin Charles Duke, Van Hoan Tran, Rujee Kyokajee Duke
  • Compounds for treatment of cancer
    Patent number: 9334242
    Abstract: The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: May 10, 2016
    Assignees: GTX, INC., UNIVERSITY OF TENNESSEE
    Inventors: Yan Lu, Chien-Ming Li, Zhao Wang, Jianjun Chen, Wei Li, James T. Dalton, Duane D. Miller, Charles Duke, Sunjoo Ahn
  • PRENYLATED HYDROXYSTILBENES
    Publication number: 20150307429
    Abstract: Prenylated stilbene compounds and the use of such compounds in the treatment of diseases and medical disorders, for example cancer, skin ageing, inflammation, bacterial or fungal infection and immunosuppression.
    Type: Application
    Filed: May 4, 2012
    Publication date: October 29, 2015
    Inventors: Colin Charles Duke, Van Hoan Tran, Rujee Kyokajee Duke
  • Compounds for treatment of cancer
    Patent number: 8822513
    Abstract: The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer.
    Type: Grant
    Filed: August 24, 2011
    Date of Patent: September 2, 2014
    Assignees: GTX, Inc., University of Tennessee Research Foundation
    Inventors: Yan Lu, Chien-Ming Li, Zhao Wang, Jianjun Chen, Wei Li, James T. Dalton, Duane D. Miller, Charles Duke, Sunjoo Ahn
  • COMPOUNDS FOR TREATMENT OF CANCER
    Publication number: 20120071524
    Abstract: The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer.
    Type: Application
    Filed: August 24, 2011
    Publication date: March 22, 2012
    Inventors: Yan Lu, Chien-Ming Li, Zhao Wang, Jianjun Chen, Wei Li, James T. DALTON, Duane D. Miller, Charles Duke, Sunjoo Ahn
  • INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR
    Publication number: 20120022121
    Abstract: Indole derivatives and analogous compounds and pharmaceutical compositions comprising the same are provided. Also provided are methods of using these compounds to inhibit tubulin polymerization in a cell associated with a proliferative disease or to treat cancer, metastatic cancer, resistant cancer or multidrug resistant cancer, including inter-alia: prostate cancer, breast cancer, melanoma, colon cancer and bladder cancer.
    Type: Application
    Filed: July 25, 2011
    Publication date: January 26, 2012
    Inventors: James T. DALTON, Duane D. MILLER, Sunjoo AHN, Charles DUKE, Dong Jin HWANG, Jun YANG
  • COMPOUNDS FOR TREATMENT OF CANCER
    Publication number: 20110257196
    Abstract: The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer.
    Type: Application
    Filed: December 29, 2010
    Publication date: October 20, 2011
    Inventors: Yan Lu, Chien-Ming Li, Zhao Wang, Jianjun Chen, Wei Li, James T. Dalton, Duane D. Miller, Charles Duke, Sunjoo Ahn
  • Indoles, Derivatives, and Analogs Thereof and Uses Therefor
    Publication number: 20090142832
    Abstract: Indole derivatives and analog compounds and pharmaceutical compositions comprising the same are provided. Also provided are methods of using these compounds to inhibit tubulin polymerization in a cell associated with a proliferative disease or to treat a cancer.
    Type: Application
    Filed: November 29, 2007
    Publication date: June 4, 2009
    Inventors: James Dalton, Duane Miller, Sunjoo Ahn, Charles Duke, III, Dong Jin Hwang, Jun Yang