Patents by Inventor Charles E. Butler

Charles E. Butler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SILK FIBROIN-DECORIN SCAFFOLDS
    Publication number: 20120251593
    Abstract: Disclosed are silk fibroin scaffolds that are fabricated with decorin proteoglycan, and methods of using these scaffolds in the repair of tissue defects in subjects. The scaffolds have biomechanical properties which makes them suitable for patient-specific design for defects where strong tensile strength is required, such as musculofascia reconstruction.
    Type: Application
    Filed: September 28, 2010
    Publication date: October 4, 2012
    Applicant: THE BAOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Anshu B. Mathur, Charles E. Butler, Vishal Gupta, Nadja K. Burns
  • Composite material for wound repair
    Publication number: 20030225355
    Abstract: A composite comprising a barrier material and a support material used for wound or tissue repair. Benefits include decreased adhesion to organs or other structures adjacent to the repair site, limited fluid flux, increased vascularization and cellular infiltration, decreased inflammation and reduced scar tissue formation.
    Type: Application
    Filed: April 1, 2003
    Publication date: December 4, 2003
    Inventor: Charles E. Butler
  • Conformable bi-laminate compression bolster and method for using same
    Publication number: 20030212359
    Abstract: A bolster dressing comprising an inner conformable layer and an outer semirigid layer for use in closing wounds and securing skin grafts or surgical flaps. This bolster dressing reduces edema, hematoma, seroma and shear of the wound bed.
    Type: Application
    Filed: March 7, 2003
    Publication date: November 13, 2003
    Inventor: Charles E. Butler
  • Method of skin regeneration using a collagen-glycosaminoglycan matrix and cultured epithelial autograft
    Patent number: 5716411
    Abstract: The present invention relates to a method of skin regeneration of a wound or burn in an animal or human. This method comprises the steps of initially covering the wound with a collagen glycosaminoglycan matrix, allowing infiltration of the grafted GC matrix by mesenchymal cells and blood vessels from healthy underlying tissue and applying a cultured epithelial autograft sheet grown from epidermal cells taken from the animal or human at a wound free site on the animal's or human's body surface. The resulting graft has excellent take rates and has the appearance, growth, maturation and differentiation of normal skin.
    Type: Grant
    Filed: February 6, 1996
    Date of Patent: February 10, 1998
    Assignees: Brigham & Womens Hospital, Massachusetts Institute of Technology, Shriners Hospitals for Crippled Children
    Inventors: Dennis P. Orgill, Charles E. Butler, Mark Barlow, Scott Ritterbush, Ioannis V. Yannas, Carolyn C. Compton
  • Method of skin regeneration using a collagen-glycosaminoglycan matrix and cultured epithelial autograft
    Patent number: 5489304
    Abstract: The present invention relates to a method of skin regeneration of a wound or burn in an animal or human. This method comprises the steps of initially covering the wound with a collagen glycosaminoglycan matrix, allowing infiltration of the grafted GC matrix by mesenchymal cells and blood vessels from healthy underlying tissue and applying a cultured epithelial autograft sheet grown from epidermal cells taken from the animal or human at a wound free site on the animal's or human's body surface. The resulting graft has excellent take rates and has the appearance, growth, maturation and differentiation of normal skin.
    Type: Grant
    Filed: April 19, 1994
    Date of Patent: February 6, 1996
    Assignees: Brigham & Women's Hospital, Shriners Hospital for Crippled Children, Massachusetts Institute of Technology, Integra LifeSciences, Corporation
    Inventors: Dennis P. Orgill, Charles E. Butler, Mark Barlow, Scott Ritterbush, Ioannis V. Yannas, Carolyn C. Compton