Patents by Inventor Charles Emala

Charles Emala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds, extracts and methods from chinese medicinal herb sophora flavescens that inhibit airway contraction
    Patent number: 10406191
    Abstract: The present invention relates to extracts of Sophora Flavescens, and compounds isolated therefrom for use in modulating airway smooth muscle contractility. Methods of creating enriched extracts of Sophora Flavescens are disclosed, as are specific compounds isolated therefrom. Methods for the treatment of disorders involving airway smooth muscle, such as asthma, using the compounds and extracts described herein are also disclosed.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: September 10, 2019
    Inventors: Xiu-Min Li, Hugh A. Sampson, Nan Yang, Kamal Srivastava, Charles Emala
  • COMPOUNDS, EXTRACTS AND METHODS FROM CHINESE MEDICINAL HERB SOPHORA FLAVESCENS THAT INHIBIT AIRWAY CONTRACTION
    Publication number: 20150359834
    Abstract: The present invention relates to extracts of Sophora Flavascens, and compounds isolated therefrom for use in modulating airway smooth muscle contractility. Methods of creating enriched extracts of Sophora Flavascens are disclosed, as are specific compounds isolated therefrom. Methods for the treatment of disorders involving airway smooth muscle, such as asthma, using the compounds and extracts described herein are also disclosed.
    Type: Application
    Filed: January 21, 2014
    Publication date: December 17, 2015
    Inventors: Xiu-Min LI, Sampson HUGH, Nan YANG, Kamal SRIVASTAVA, Charles EMALA
  • SELECTIVE AMPLIFICATION AND DETECTION OF MUTANT GENE ALLELES
    Publication number: 20140322717
    Abstract: The present invention provides methods for selectively amplifying a mutant allele of a gene. These methods include (a) contacting a sample containing a mutant and a normal allele of a gene with at least one primer that selectively modifies the normal allele of the gene and causes further amplification of the normal allele to fail or to be substantially reduced; and (b) selectively amplifying the mutant allele of the gene or a portion thereof. Other methods for detecting a mutant allele of a gene in a sample are also provided.
    Type: Application
    Filed: November 16, 2012
    Publication date: October 30, 2014
    Inventors: Dingbang Xu, Charles Emala