Abstract: A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.

Abstract: A bicycle has a front fork, within which the front wheel is mounted, attached to the head tube. Extending downwardly from each end of a lateral member are downwardly projecting forks, each comprising a primary portion, the respective primary portions extending downwardly and substantially parallel to each other. The longitudinal axes of both the main portion and a rider's lower leg are aligned. By aligning the wakes created by the forks and the lower leg a reduction in overall system drag is provided. Additionally or alternatively, the rear wheel may be provided between downwardly projecting stays, each comprising a primary portion, the respective primary portions extending downwardly and substantially parallel to each other. By aligning the downwardly projecting stays with the lower leg beneficial drag reduction is achieved.

Abstract: The invention comprises, in an embodiment, a resealable packaging structure comprising a container having a bottom and at least one sidewall extending upwardly therefrom, wherein the sidewall terminates in a flange. A flexible resealable lid is sealed to the flange. The lid comprises a polyethylene terephthalate layer disposed adjacent the flange, a pressure sensitive adhesive layer disposed adjacent the polyethylene terephthalate layer, and an oriented polypropylene layer disposed adjacent the pressure sensitive adhesive layer. The polyethylene terephthalate layer comprises a laser scored line which penetrates through the thickness of the inner layer but not through the outer layer and defines an opening portion that can be lifted out of the plane of the inner layer, thereby creating an opening through the lid defined by the laser score line.

Abstract: A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.

Abstract: A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.

Abstract: A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.

Abstract: The invention comprises, in an embodiment, a resealable packaging structure comprising a container having a bottom and at least one sidewall extending upwardly therefrom, wherein the sidewall terminates in a flange. A flexible resealable lid is sealed to the flange. The lid comprises a polyethylene terephthalate layer disposed adjacent the flange, a pressure sensitive adhesive layer disposed adjacent the polyethylene terephthalate layer, and an oriented polypropylene layer disposed adjacent the pressure sensitive adhesive layer. The polyethylene terephthalate layer comprises a laser scored line which penetrates through the thickness of the inner layer but not through the outer layer and defines an opening portion that can be lifted out of the plane of the inner layer, thereby creating an opening through the lid defined by the laser score line.

Abstract: A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.

Abstract: The present invention relates to the use of the measure of anelloviral load for the determination of immunosuppression. More precisely, the present invention provides a method for characterizing the immunosuppressed or non-immunosuppressed status of a subject, comprising the steps of determining the anelloviral load from a biological sample of the said subject, and determining from the said comparison the immunosuppressed or non-immunosuppressed status. The determination of the immunosuppressed status of the subject can then be used to design or adapt a therapeutic treatment.

Abstract: The present invention relates to the use of the measure of anelloviral load for the determination of immunosuppression. More precisely, the present invention provides a method for characterizing the immunosuppressed or non-immunosuppressed status of a subject, comprising the steps of determining the anelloviral load from a biological sample of the said subject, and determining from the said comparison the immunosuppressed or non-immunosuppressed status. The determination of the immunosuppressed status of the subject can then be used to design or adapt a therapeutic treatment.

Abstract: According to a further exemplary embodiment, a wardrobe may be provided. The wardrobe may include a receiving element located in a housing that may be configured to receive and dispense clothing items. Each clothing item may include a unique RFID tag and a number of RFID readers may be connected to a computing means configured to obtain information held in each RFID tag. The wardrobe may further include a linear actuator proximate a top surface of the housing, the linear actuator may be controlled by the computing means. The linear actuator may be coupled to a gripper assembly on one end. Additionally, the wardrobe may include a number of hangers that may be disposed on one or more inner surfaces of the housing, each hanger may be configured to store one or more of the clothing items. A display screen may be embedded on the outer surface of the housing.

Abstract: A wardrobe may be provided. The wardrobe may include a receiving element located in a housing that may be configured to receive and dispense clothing items. Each clothing item may include a unique RFID tag and a number of RFID readers may be connected to a computer configured to obtain information held in each RFID tag. The wardrobe may further include a linear actuator proximate a top surface of the housing; the linear actuator may be controlled by the computer. The linear actuator may be coupled to a gripper assembly on one end. Additionally, the wardrobe may include a number of hangers that may be disposed on one or more inner surfaces of the housing, each hanger may be configured to store one or more of the clothing items. A display screen may be embedded on the outer surface of the housing.

Abstract: A wardrobe may be provided. The wardrobe may include a receiving element located in a housing that may be configured to receive and dispense clothing items. Each clothing item may include a unique RFID tag and a number of RFID readers may be connected to a computer configured to obtain information held in each RFID tag. The wardrobe may further include a linear actuator proximate a top surface of the housing; the linear actuator may be controlled by the computer. The linear actuator may be coupled to a gripper assembly on one end. Additionally, the wardrobe may include a number of hangers that may be disposed on one or more inner surfaces of the housing, each hanger may be configured to store one or more of the clothing items. A display screen may be embedded on the outer surface of the housing.

Abstract: A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.

Abstract: According to a further exemplary embodiment, a wardrobe may be provided. The wardrobe may include a receiving element located in a housing that may be configured to receive and dispense clothing items. Each clothing item may include a unique RFID tag and a number of RFID readers may be connected to a computing means configured to obtain information held in each RFID tag. The wardrobe may further include a linear actuator proximate a top surface of the housing, the linear actuator may be controlled by the computing means. The linear actuator may be coupled to a gripper assembly on one end. Additionally, the wardrobe may include a number of hangers that may be disposed on one or more inner surfaces of the housing, each hanger may be configured to store one or more of the clothing items. A display screen may be embedded on the outer surface of the housing.

Abstract: The present invention relates to the use of the measure of anelloviral load for the determination of immunosuppression. More precisely, the present invention provides a method for characterizing the immunosuppressed or non-immunosuppressed status of a subject, comprising the steps of determining the anelloviral load from a biological sample of the said subject, and determining from the said comparison the immunosuppressed or non-immunosuppressed status. The determination of the immunosuppressed status of the subject can then be used to design or adapt a therapeutic treatment.

Abstract: The present invention relates to methods for treating intestinal fluid balance disorders and modulating intestinal fluid secretion and absorption using calcimimetics and calcilytics.

Abstract: A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.

Abstract: A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.

Abstract: A flexible packaging laminate is formed to have a built-in opening and reclose feature by forming the laminate as a two-part structure having an outer structure joined in face-to-face relation with an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting an opening portion (e.g., a flap or the like) of the two structures out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate.