Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.

Abstract: A simulated abdominal wall model that is ideal for practicing laparoscopic first entry surgical techniques is provided. The model includes a simulated abdominal wall portion captured between two frame elements of a support. The support is connectable to a surgical trainer. When connected to the trainer, the model provides a penetrable abdominal tissue portion for accessing an internal cavity of the trainer. The simulated abdominal wall includes a plurality of layers including a skin layer, a fabric posterior rectus sheath layer, a simulated fat layer of low-resilience polyurethane foam and at least two layers that provide distinctive haptic feedback upon penetration of the simulated transversalis fascia and muscle layers. The simulated abdominal wall includes a simulated umbilicus across several layers of simulated tissue.

Abstract: A light source or projector for a near-eye display includes a light source subassembly optically coupled to a waveguide concentrator. The light source subassembly may include several semiconductor chips each hosting an array of emitters such s superluminescent light-emitting diodes. The semiconductor chips may be disposed side-by-side, with their emitting sides or facets coupled to the waveguide concentrator, which provides a tight array of output light ports on a common output plane of the concentrator. The output diverging beams at the array of output light ports are coupled to a collimator, which collimates the beams and couples them to an angular scanner for scanning the collimated light beams together across the field of view of the display.

Abstract: A method of providing a user with an individualized health platform, includes collecting a user's health and care data, organizing the collected health and care data into a problem oriented health record, drafting health goals and a care plan for the user with the aid of a health coach, vetting the health goals and care plan using a data and analytics system to assure that the health goals and care plan are supported by peer reviewed health and clinical literature, producing individualized guidance options for addressing new acute or chronic issues, managing existing health issues, achieving the health goals, and adhering to the care plan based on the user's problem oriented health record, monitoring the user's achievements with respect to the user's health goals and adherence to the care plan, and providing additional guidance options based on the user's new health and care issues and the user's achievements and adherence.

Abstract: An index bracket assembly positions an external apparatus on a facemask having top and side portions extending to lower corners. A U-shaped frame connected to the external apparatus has top and side openings and a U-shaped bearing surface having orthogonally extending feet at its opposite ends. The U-shaped bearing surface extends along the top and side portions and the feet abut against the lower corners of the facemask. A three-point harness has a top strap connected to the top opening and side straps are connected to the side openings. The top strap and side straps each have a separate adjustable buckle component connected together for tightening them and pulling the U-shaped bearing surface against the top and side portions of the facemask. A layer of compliant material on the U-shaped surface elastically yields to the top and side portions of the facemask to prevent slippage.

Abstract: A submersible vehicle comprising a plurality of rigid submersible vessels 2, 3, some of which, 2, include propulsion means and some of which, 3, do not include propulsion means, the rigid submersible vessels being coupled by resilient couplings which are adapted to transmit pulling and braking forces between adjacent rigid submersible vessels. Steering means and position sensing means is provided on at least some of the submersible vessels whereby to ensure that the following submersible vessels follow exactly the lead vessel to avoid fixed obstructions.

Abstract: A parachutist navigation system includes a display attached to a side vision area of a parachutist's goggles, a navigation pod attached to the parachutist's helmet, and a remotely located controller. The navigation pod supports therein a GPS receiver and a processor provided with mission data supplied by the controller. The processor uses the mission data and GPS signals to generate a plurality of display-formatted data sets. Coupled to the processor is an user-controlled input device used to select at least one of the plurality of display-formatted data sets for output to the display.

Abstract: A dive mask display system integrates a plurality of components in the mask's frame. These components can include: a radio frequency (RF) antenna for receiving RF signals indicative of dive information, a display that is directly viewable in a peripheral vision area of the diver but outside of the field of view defined by the mask's lens(es), a diver-controlled controller, and a depth sensor. The various monitored information, as well as bottom time tracked by the controller, can be displayed simultaneously.

Abstract: A submersible vehicle comprising a plurality of rigid submersible vessels 2, 3, some of which, 2, include propulsion means and some of which, 3, do not include propulsion means, the rigid submersible vessels being coupled by resilient couplings which are adapted to transmit pulling and braking forces between adjacent rigid submersible vessels and also to limit the maximum angle between the axis of adjacent submersible vessels to 10.

Abstract: The present invention relates to a method for quantitatively assaying the presence of DSP toxins such as okadaic acid and dinophysistoxin-1 in marine samples. The method comprises the steps of preparing a marine extract, fractionating the prepared marine extract and selecting the extract fraction containing the toxin to be assayed. Once the desired extract fraction has been selected, a labelled substrate for protein phosphatase and at least one protein phosphatase are added to the extract in an assay. The amount of toxin present is quantitatively measured by the ability of the extract fraction to inhibit catalysis, mainly dephosphorylation, of the labelled substrate by protein phosphatases, such as phosphatase-1 (PP1) or phosphatase-2A (PP2A). Preferably, the method of the present invention is used to assay the presence of okadaic acid in marine organisms such as mussels, oysters, scallops, phytoplankton and the like.