Patents by Inventor Charles K. York

Charles K. York has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kits for isolating biological target materials using silica magnetic particles
    Publication number: 20020086326
    Abstract: The present invention provides methods for isolating biological target materials, particularly nucleic acids, such as DNA or RNA or hybrid molecules of DNA and RNA, from other substances in a medium using silica magnetic particles. The methods of the present invention involve forming a complex of the silica magnetic particles and the biological target material in a mixture of the medium and particles, separating the complex from the mixture using external magnetic force, and eluting the biological target material from the complex. The preferred embodiments of magnetic silica particles used in the methods and kits of the present invention are capable of forming a complex with at least 2 &mgr;g of biological target material per milligram of particle, and of releasing at least 60% of the material from the complex in the elution step of the method.
    Type: Application
    Filed: January 7, 2002
    Publication date: July 4, 2002
    Applicant: Promega Corporation
    Inventors: Craig E. Smith, Charles K. York
  • Kits for isolating biological target materials using silica magnetic particles
    Patent number: 6368800
    Abstract: The present invention provides methods for isolating biological target materials, particularly nucleic acids, such as DNA or RNA or hybrid molecules of DNA and RNA, from other substances in a medium using silica magnetic particles. The methods of the present invention involve forming a complex of the silica magnetic particles and the biological target material in a mixture of the medium and particles, separating the complex from the mixture using external magnetic force, and eluting the biological target material from the complex. The preferred embodiments of magnetic silica particles used in the methods and kits of the present invention are capable of forming a complex with at least 2 &mgr;g of biological target material per milligram of particle, and of releasing at least 60% of the material from the complex in the elution step of the method.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: April 9, 2002
    Assignee: Promega Corporation
    Inventors: Craig E. Smith, Charles K. York
  • Methods of isolating biological target materials using silica magnetic particles
    Patent number: 6027945
    Abstract: The present invention provides methods for isolating biological target materials, particularly nucleic acids, such as DNA or RNA or hybrid molecules of DNA and RNA, from other substances in a medium using silica magnetic particles. The methods of the present invention involve forming a complex of the silica magnetic particles and the biological target material in a mixture of the medium and particles, separating the complex from the mixture using external magnetic force, and eluting the biological target material from the complex. The preferred embodiments of magnetic silica particles used in the methods and kits of the present invention are capable of forming a complex with at least 2 .mu.g of biological target material per milligram of particle, and of releasing at least 60% of the material from the complex in the elution step of the method.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: February 22, 2000
    Assignee: Promega Corporation
    Inventors: Craig E. Smith, Charles K. York