Patents by Inventor Charles Kung

Charles Kung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyruvate kinase modulators and use thereof
    Patent number: 11872225
    Abstract: Described herein are methods of using compounds of Formula (I) to modulate PKM2 activity in a subject. These compounds are represented by Formula (I): wherein R1, R2, L1, and L2 are as defined herein.
    Type: Grant
    Filed: January 27, 2022
    Date of Patent: January 16, 2024
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Giovanni Cianchetta, Charles Kung, Tao Liu, Anil Kumar Padyana, Zhihua Sui, Zhenwei Cai, Dawei Cui, Jingjing Ji
  • Pyruvate kinase modulators and use thereof
    Patent number: 11464775
    Abstract: Described herein are methods of using compounds of Formula (I) to modulate PKM2 activity in a subject. These compounds are represented by Formula (I): wherein R1, R2, L1, and L2 are as defined herein.
    Type: Grant
    Filed: August 15, 2018
    Date of Patent: October 11, 2022
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Giovanni Cianchetta, Charles Kung, Tao Liu, Anil Kumar Padyana, Zhihua Sui, Zhenwei Cai, Dawei Cui, Jingjing Ji
  • PYRUVATE KINASE MODULATORS AND USE THEREOF
    Publication number: 20220233541
    Abstract: Described herein are methods of using compounds of Formula (I) to modulate PKM2 activity in a subject. These compounds are represented by Formula (I): wherein R1, R2, L1, and L2 are as defined herein.
    Type: Application
    Filed: January 27, 2022
    Publication date: July 28, 2022
    Inventors: Giovanni Cianchetta, Charles Kung, Tao Liu, Anil Kumar Padyana, Zhihua Sui, Zhenwei Cai, Dawei Cui, Jingjing Ji
  • METHODS OF USING PYRUVATE KINASE ACTIVATORS
    Publication number: 20220211697
    Abstract: Described herein are methods for using compounds that activate pyruvate kinase.
    Type: Application
    Filed: December 15, 2021
    Publication date: July 7, 2022
    Inventors: Samuel V. Agresta, Yue Chen, Marvin Barry Cohen, Lenny Dang, Charles Kung, Elizabeth A. Merica, Bruce Alan Silver, Hua Yang
  • Methods of using pyruvate kinase activators
    Patent number: 11234976
    Abstract: Described herein are methods for using compounds that activate pyruvate kinase.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: February 1, 2022
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Samuel V. Agresta, Yue Chen, Marvin B. Cohen, Lenny Dang, Charles Kung, Elizabeth A. Merica, Bruce A. Silver, Hua Yang
  • PYRUVATE KINASE MODULATORS AND USE THEREOF
    Publication number: 20200206225
    Abstract: Described herein are methods of using compounds of Formula (I) to modulate PKM2 activity in a subject. These compounds are represented by Formula (I): wherein R1, R2, L1, and L2 are as defined herein.
    Type: Application
    Filed: August 15, 2018
    Publication date: July 2, 2020
    Applicant: Agios Pharmaceuticals, Inc.
    Inventors: Giovanni Cianchetta, Charles Kung, Tao Liu, Anil Kumar Padyana, Zhihua Sui, Zhenwei Cai, Dawei Cui, Jingjing Ji
  • METHODS OF USING PYRUVATE KINASE ACTIVATORS
    Publication number: 20200030322
    Abstract: Described herein are methods for using compounds that activate pyruvate kinase.
    Type: Application
    Filed: June 10, 2016
    Publication date: January 30, 2020
    Applicant: Agios Pharmaceuticals, Inc.
    Inventors: Samuel V. Agresta, Yue Chen, Marvin B. Cohen, Lenny Dang, Charles Kung, Elizabeth A. Merica, Bruce A. Silver, Hua Yang
  • ACTIVATORS OF PYRUVATE KINASE M2 AND METHODS OF TREATING DISEASE
    Publication number: 20170007608
    Abstract: The invention described herein features methods, compositions, and kits that utilize activators of pyruvate kinase M2 (PKM2) for the treatment or amelioration of disorders related to PKM2 function and characterized by abnormally low levels of serine.
    Type: Application
    Filed: September 20, 2016
    Publication date: January 12, 2017
    Inventor: Charles Kung
  • ACTIVATORS OF PYRUVATE KINASE M2 AND METHODS OF TREATING DISEASE
    Publication number: 20140249150
    Abstract: The invention described herein features methods, compositions, and kits that utilize activators of pyruvate kinase M2 (PKM2) for the treatment or amelioration of disorders related to PKM2 function and characterized by abnormally low levels of serine.
    Type: Application
    Filed: October 12, 2012
    Publication date: September 4, 2014
    Applicant: AGIOS PHARMACEUTICALS, INC
    Inventor: Charles Kung